Effect of right ventricular apical pacing in survivors of myocardial infarction

Carmine Muto; Luigi Ascione; Michelangelo Canciello; Giovanni Carreras; Raffaele Iengo; Luca Ottaviano; Raimondo Calvanese; Maria Accadia; Eduardo Celentano; Carmine Ciardiello; Bernardino Tuccillo

doi:10.1111/j.1540-8159.2008.02279.x

Effect of right ventricular apical pacing in survivors of myocardial infarction

Carmine Muto^*
, Luigi Ascione
, Michelangelo Canciello
, Giovanni Carreras
, Raffaele Iengo
, Luca Ottaviano
, Raimondo Calvanese
, Maria Accadia
, Eduardo Celentano
, Carmine Ciardiello
, Bernardino Tuccillo

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

Abstract

Background:

Much information is available regarding the possible negative effects of long-term right ventricular (RV) apical pacing, which may cause worsening of heart failure. However, very limited data are available regarding the effects of RV pacing in patients with a previous myocardial infarction (MI).

Methods and Results:

We screened 115 consecutive post-MI patients and matched a group of 29 pacemaker (PM) recipients with a group of 49 unpaced patients, for age, left ventricular (LV) ejection fraction, and site of MI. During a median follow-up of 54 months, echocardiograms showed a decrease in LV ejection fraction in the paced group, from 51 ± 10 to 39 ± 11 (P < 0.01), and a minimal change in the unpaced group, from 57 ± 8 to 56 ± 7 (P = 0.98). Similar change was observed in systolic and diastolic diameters and volumes.

Conclusions:

The study showed that, in post-MI patients, RV apical pacing was associated with a worsening of LV function, suggesting that, among MI survivors, the need for a PM is a marker of worse outcome.

Original language	English
Pages (from-to)	S173-S176
Journal	PACE - Pacing and Clinical Electrophysiology
Volume	32
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1111/j.1540-8159.2008.02279.x
Publication status	Published - Mar 2009
Externally published	Yes

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title = "Effect of right ventricular apical pacing in survivors of myocardial infarction",

abstract = "Background: Much information is available regarding the possible negative effects of long-term right ventricular (RV) apical pacing, which may cause worsening of heart failure. However, very limited data are available regarding the effects of RV pacing in patients with a previous myocardial infarction (MI). Methods and Results: We screened 115 consecutive post-MI patients and matched a group of 29 pacemaker (PM) recipients with a group of 49 unpaced patients, for age, left ventricular (LV) ejection fraction, and site of MI. During a median follow-up of 54 months, echocardiograms showed a decrease in LV ejection fraction in the paced group, from 51 ± 10 to 39 ± 11 (P < 0.01), and a minimal change in the unpaced group, from 57 ± 8 to 56 ± 7 (P = 0.98). Similar change was observed in systolic and diastolic diameters and volumes. Conclusions: The study showed that, in post-MI patients, RV apical pacing was associated with a worsening of LV function, suggesting that, among MI survivors, the need for a PM is a marker of worse outcome.",

author = "Carmine Muto and Luigi Ascione and Michelangelo Canciello and Giovanni Carreras and Raffaele Iengo and Luca Ottaviano and Raimondo Calvanese and Maria Accadia and Eduardo Celentano and Carmine Ciardiello and Bernardino Tuccillo",

year = "2009",

month = mar,

doi = "10.1111/j.1540-8159.2008.02279.x",

language = "English",

volume = "32",

pages = "S173--S176",

journal = "PACE - Pacing and Clinical Electrophysiology",

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number = "SUPPL. 1",

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TY - JOUR

T1 - Effect of right ventricular apical pacing in survivors of myocardial infarction

AU - Muto, Carmine

AU - Ascione, Luigi

AU - Canciello, Michelangelo

AU - Carreras, Giovanni

AU - Iengo, Raffaele

AU - Ottaviano, Luca

AU - Calvanese, Raimondo

AU - Accadia, Maria

AU - Celentano, Eduardo

AU - Ciardiello, Carmine

AU - Tuccillo, Bernardino

PY - 2009/3

Y1 - 2009/3

N2 - Background: Much information is available regarding the possible negative effects of long-term right ventricular (RV) apical pacing, which may cause worsening of heart failure. However, very limited data are available regarding the effects of RV pacing in patients with a previous myocardial infarction (MI). Methods and Results: We screened 115 consecutive post-MI patients and matched a group of 29 pacemaker (PM) recipients with a group of 49 unpaced patients, for age, left ventricular (LV) ejection fraction, and site of MI. During a median follow-up of 54 months, echocardiograms showed a decrease in LV ejection fraction in the paced group, from 51 ± 10 to 39 ± 11 (P < 0.01), and a minimal change in the unpaced group, from 57 ± 8 to 56 ± 7 (P = 0.98). Similar change was observed in systolic and diastolic diameters and volumes. Conclusions: The study showed that, in post-MI patients, RV apical pacing was associated with a worsening of LV function, suggesting that, among MI survivors, the need for a PM is a marker of worse outcome.

AB - Background: Much information is available regarding the possible negative effects of long-term right ventricular (RV) apical pacing, which may cause worsening of heart failure. However, very limited data are available regarding the effects of RV pacing in patients with a previous myocardial infarction (MI). Methods and Results: We screened 115 consecutive post-MI patients and matched a group of 29 pacemaker (PM) recipients with a group of 49 unpaced patients, for age, left ventricular (LV) ejection fraction, and site of MI. During a median follow-up of 54 months, echocardiograms showed a decrease in LV ejection fraction in the paced group, from 51 ± 10 to 39 ± 11 (P < 0.01), and a minimal change in the unpaced group, from 57 ± 8 to 56 ± 7 (P = 0.98). Similar change was observed in systolic and diastolic diameters and volumes. Conclusions: The study showed that, in post-MI patients, RV apical pacing was associated with a worsening of LV function, suggesting that, among MI survivors, the need for a PM is a marker of worse outcome.

UR - https://www.scopus.com/pages/publications/60849136029

U2 - 10.1111/j.1540-8159.2008.02279.x

DO - 10.1111/j.1540-8159.2008.02279.x

M3 - Article

C2 - 19250087

AN - SCOPUS:60849136029

SN - 0147-8389

VL - 32

SP - S173-S176

JO - PACE - Pacing and Clinical Electrophysiology

JF - PACE - Pacing and Clinical Electrophysiology

IS - SUPPL. 1

ER -

Effect of right ventricular apical pacing in survivors of myocardial infarction

Abstract

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