Effect of various kinds of cervical spinal surgery on clinical outcomes: A systematic review and meta-analysis

Arianne Verhagen, Marienke van Middelkoop, SM Rubinstein, R Ostelo, W Jacobs, W Peul, Bart Koes, MW van Tulder

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)


The choice of a specific surgical technique should be based on its benefits and harms. Previous reviews have shown that the benefit of surgery over conservative care is not clearly demonstrated in patients with disorders of the cervical spine. Also, no additional benefit of fusion upon anterior decompression techniques could be found. A clear overview of other surgical techniques is lacking. We therefore aimed to assess the benefits and harms of cervical spinal surgery in patients with cervical disorders. We searched MEDLINE, EMBASE, CINAHL, and CENTRAL up to June 2012. Randomized controlled trials (RCTs) were selected which included adults with cervical disorders receiving a surgical intervention and that reported at least 1 clinically relevant outcome measure (eg, pain, function, recovery). Two authors independently assessed the risk of bias using the criteria recommended by the Cochrane Back Review Group and extracted the data. The quality of the evidence was rated using the GRADE method. We i
Original languageUndefined/Unknown
Pages (from-to)2388-2396
Number of pages9
Issue number11
Publication statusPublished - 2013

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