Abstract
Cytomegalovirus (CMV)-carrying individuals have significantly higher levels of effector memory and late memory T lymphocytes in their blood than non-carriers. To date, it is well recognized that the central nervous system is subjected to active immunosurveillance, as evidenced by the presence of central memory T cells in cerebrospinal fluid (CSF) of healthy individuals. In order to investigate whether levels of effector memory and late memory T cells were also increased in the CSF of CMV-carrying individuals, we characterized CD4+ and CD8+ T-cell subsets in CSF and blood of both groups. Effector memory and late memory T cells were only rarely seen in CSF, which was similar in CMV carriers and non-carriers. In conclusion, there was no demonstrable difference in the numbers of CSF effector memory and late memory T cells between CMV seronegative and CMV seropositive individuals. (c) 2013 International Clinical Cytometry Society
Original language | Undefined/Unknown |
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Pages (from-to) | 218-221 |
Number of pages | 4 |
Journal | Cytometry Part B-Clinical Cytometry |
Volume | 84B |
Issue number | 4 |
DOIs | |
Publication status | Published - 2013 |
Research programs
- EMC MM-03-44-06