TY - JOUR
T1 - Effects of vitamin D-3 supplementation and UVb exposure on the growth and plasma concentration of vitamin D-3 metabolites in juvenile bearded dragons (Pogona vitticeps)
AU - Oonincx, D. G. A. B.
AU - Stevens, Y.
AU - van den Borne, J. J. G. C.
AU - van Leeuwen, J. P. T. M.
AU - Hendriks, W. H.
PY - 2010/6
Y1 - 2010/6
N2 - The effectiveness of dietary vitamin D-3 and UVb exposure on plasma vitamin D metabolites in growing bearded dragons (Pogona vitticeps) was studied. A total of 84 (40 males and 44 females) newly hatched bearded dragons were allocated to six levels of oral vitamin D-3 supplementation (0 to 400%) or six UVb exposure times (2 to 12 h). At 3 and 6 months of age, blood samples were obtained from each animal and analysed for 25(OH)D-3 and 1,25 (OH)(2)D-3. At 3 months of age, plasma concentrations of 25(OH)D-3 did not increase with increasing vitamin D-3 supplementation unlike the 1,25(OH)(2)D-3. At 6 months of age, plasma concentrations of both 25(OH)D-3 and 1,25 (OH)(2)D-3 increased with increasing vitamin D-3 supplementation. Plasma concentrations in UVb-exposed animals were 18 times higher for 25(OH)D-3 (178.4 +/- 9.0 vs. 9.9 +/- 1.3 nmol/L) and 5.3 times higher for 1,25(OH)(2)D-3 (1.205 +/- 0.100 vs. 0.229 +/- 0.025 nmol/L) than in vitamin D-3 supplemented animals at 6 months of age. This study shows that 2 h of UVb exposure enables adequate physiological concentrations of plasma vitamin D metabolites to be maintained in growing bearded dragons. Oral supplementation of vitamin D-3 is ineffective in raising plasma concentrations of 25(OH)D-3 and 1,25(OH)(2)D-3 to concentrations observed in UVb-exposed animals. (C) 2010 Elsevier Inc. All rights reserved.
AB - The effectiveness of dietary vitamin D-3 and UVb exposure on plasma vitamin D metabolites in growing bearded dragons (Pogona vitticeps) was studied. A total of 84 (40 males and 44 females) newly hatched bearded dragons were allocated to six levels of oral vitamin D-3 supplementation (0 to 400%) or six UVb exposure times (2 to 12 h). At 3 and 6 months of age, blood samples were obtained from each animal and analysed for 25(OH)D-3 and 1,25 (OH)(2)D-3. At 3 months of age, plasma concentrations of 25(OH)D-3 did not increase with increasing vitamin D-3 supplementation unlike the 1,25(OH)(2)D-3. At 6 months of age, plasma concentrations of both 25(OH)D-3 and 1,25 (OH)(2)D-3 increased with increasing vitamin D-3 supplementation. Plasma concentrations in UVb-exposed animals were 18 times higher for 25(OH)D-3 (178.4 +/- 9.0 vs. 9.9 +/- 1.3 nmol/L) and 5.3 times higher for 1,25(OH)(2)D-3 (1.205 +/- 0.100 vs. 0.229 +/- 0.025 nmol/L) than in vitamin D-3 supplemented animals at 6 months of age. This study shows that 2 h of UVb exposure enables adequate physiological concentrations of plasma vitamin D metabolites to be maintained in growing bearded dragons. Oral supplementation of vitamin D-3 is ineffective in raising plasma concentrations of 25(OH)D-3 and 1,25(OH)(2)D-3 to concentrations observed in UVb-exposed animals. (C) 2010 Elsevier Inc. All rights reserved.
UR - https://www.scopus.com/pages/publications/77952011112
U2 - 10.1016/j.cbpb.2010.02.008
DO - 10.1016/j.cbpb.2010.02.008
M3 - Article
C2 - 20206712
AN - SCOPUS:77952011112
SN - 1096-4959
VL - 156
SP - 122
EP - 128
JO - Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology
JF - Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology
IS - 2
ER -