Efficacy of Plasma Exchange in Myasthenia Gravis Following Long COVID in a Resource-Limited Context: A Case Report

  • Rosita Bihariesingh-Sanchit
  • , Rakesh Bansie
  • , Rocade Ma
  • , Sharon Veenbergen
  • , Dimitri A. Diavatopoulos
  • , Marien I. de Jonge
  • , Arno Nierich

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

This case report describes the development of myasthenia gravis (MG) in a 71-year-old
male patient with long COVID and outlines the management of an MG exacerbation. The patient
exhibited significant symptoms, including fatigue, cognitive impairment, dysphagia and dysar
thria. Although transient improvement was observed after treatment with pyridostigmine, the pa
tient's condition later worsened, with marked axial and buccopharyngeal weakness. Symptom relief
was finally achieved with plasmapheresis using a low-volume crossflow gravity-driven method.
This case highlights the potential long-term impact of COVID-19 on autoimmune disorders such as
MG and emphasizes the need for vigilance in managing post-COVID neurological complications.
Original languageEnglish
JournalBrazilian Journal of Case Reports
Volume5
Issue number1
DOIs
Publication statusPublished - 9 Jun 2025

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