Elastic stent recoil in coronary total occlusions: Comparison of durable-polymer zotarolimus eluting stent and ultrathin strut bioabsorbable-polymer sirolimus eluting stent

Riccardo Improta, Paola Scarparo, Jeroen Wilschut, Quinten Wolff, Joost Daemen, Wijnand K. Den Dekker, Felix Zijlstra, Nicolas M. Van Mieghem, Roberto Diletti*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
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Abstract

Objectives: To compare stent recoil (SR) of the thin-strut durable-polymer Zotarolimus-eluting stent (dp-ZES) and the ultrathin-strut bioabsorbable-polymer Sirolimus-eluting stent (bp-SES) in chronic total occlusions (CTOs) and to investigate the predictors of high SR in CTOs. Background: Newer ultrathin drug eluting stent might be associated with lower radial force and higher elastic recoil due to the thinner strut design, possibly impacting on the rate of in-stent restenosis and thrombosis. Methods: Between January 2017 and November 2019, consecutive patients with CTOs undergoing percutaneous coronary intervention were evaluated. Only patients treated with dp-ZES or bp-SES were included and stratified accordingly. Quantitative coronary angiography analysis was used to assess absolute SR, relative SR, absolute focal SR, relative focal SR, high absolute, and high relative focal SR. Results: A total of 128 lesions (67 treated with dp-ZES and 61 with bp-SES) in 123 patients were analyzed. Between bp-SES and dp-ZES no differences were found in absolute SR (p =.188), relative SR (p =.138), absolute focal SR (p =.069), and relative focal SR (p =.064). High absolute and high relative focal SR occurred more frequently in bp-SES than in dp-ZES (p =.004 and p =.015). Bp-SES was a predictor of high absolute focal SR (Odds ratio [OR] 3.29, 95% confidence interval [CI] 1.50–7.22, p =.003]. High-pressure postdilation and bp-SES were predictors of high relative focal SR (OR 2.22, 95% CI 1.01–4.86, p =.047; OR 2.74, 95% CI 1.24–6.02, p =.012, respectively). Conclusions: Both stents showed an overall low SR. However, ultra-thin strut bp-SES was a predictor of high absolute and high relative focal SR.

Original languageEnglish
Pages (from-to)88-97
Number of pages10
JournalCatheterization and Cardiovascular Interventions
Volume99
Issue number1
Early online date7 May 2021
DOIs
Publication statusPublished - 1 Jan 2022

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© 2021 The Authors. Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC.

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