Emergence of a novel GII.17 norovirus - End of the GII.4 era?

Miranda de Graaf, Janko Beek, H Vennema, AT Podkolzin, J Hewitt, F Bucardo, K Templeton, J Mans, J Nordgren, G Reuter, M Lynch, LD Rasmussen, N Iritani, MC Chan, V Martella, K Ambert-Balay, J Vinje, PA White, Marion Koopmans

Research output: Contribution to journalArticleAcademic

194 Citations (Scopus)


In the winter of 2014/15 a novel GII.P17-GII.17 norovirus strain (GII.17 Kawasaki 2014) emerged, as a major cause of gastroenteritis outbreaks in China and Japan. Since their emergence these novel GII.P17-GII.17 viruses have replaced the previously dominant GII.4 genotype Sydney 2012 variant in some areas in Asia but were only detected in a limited number of cases on other continents. This perspective provides an overview of the available information on GII.17 viruses in order to gain insight in the viral and host characteristics of this norovirus genotype. We further discuss the emergence of this novel GII.P17-GII.17 norovirus in context of current knowledge on the epidemiology of noroviruses. It remains to be seen if the currently dominant norovirus strain GII.4 Sydney 2012 will be replaced in other parts of the world. Nevertheless, the public health community and surveillance systems need to be prepared in case of a potential increase of norovirus activity in the next seasons caused by this novel GII.P17-GII.17 norovirus.
Original languageUndefined/Unknown
Pages (from-to)8-15
Number of pages8
Issue number26
Publication statusPublished - 2015

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