Epidemiology of Cerebral Palsy in Adulthood: A Systematic Review and Meta-analysis of the Most Frequently Studied Outcomes

Marloes van Gorp, Sander R. Hilberink, Suzie Noten, Joyce L. Benner, Henk J. Stam, Wilma M. A. van Der Slot, Marij E. Roebroeck*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

36 Citations (Scopus)
47 Downloads (Pure)


Objective: To describe the epidemiology of health status, impairments, activities and participation in adults with cerebral palsy (CP).Data Sources: Embase, MEDLINE, Web of Science, PsycINFO, Cumulative Index to Nursing and Allied Health, Cochrane, and Google Scholar were searched for 3 themes ("cerebral palsy," "adult," and "outcome assessment") in literature published between January 2000 and December 2018.Study Selection: Full-article peer-reviewed English journal articles on descriptive, observational, or experimental studies describing the most studied outcomes in adults with CP (n >= 25, age >= 18y) were included. Studies were included in the analyses if frequently studied outcomes were described in at least 3 studies using similar methods of assessment.Data Extraction: Data were extracted independently by 2 authors from 65 articles (total N=28,429) using a standardized score sheet.Data Synthesis: Meta-analyses revealed that overall, on average 65.1% (95% confidence interval [CI], 55.1-74.5) of adults with CP experienced pain, 57.9% (95% CI, 51.1-64.6) were ambulant, 65.5% (95% CI, 61.2-69.7) had little or no limitation in manual ability, 18.2% (95% CI, 10.6-27.2) had tertiary education, 39.2% (95% CI, 31.5;47.1) were employed, and 29.3% (95% CI, 9.0-55.3) lived independently. In adults without intellectual disability, proportions of individuals who were ambulant (72.6% [95% CI, 58.8-84.5]) and lived independently (90.0% [95% CI, 83.8-94.9]) were higher (P=.014 and P
Original languageEnglish
Pages (from-to)1041-1052
Number of pages12
JournalArchives of Physical Medicine and Rehabilitation
Issue number6
Publication statusPublished - Jun 2020


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