Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm

Rami Nachabe; BHW Hendriks; AE Desjardins; M van der Voort; MB van der Mark; Dick Sterenborg

doi:10.1117/1.3454392

Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm

Rami Nachabe, BHW Hendriks, AE Desjardins, M van der Voort, MB van der Mark, Dick Sterenborg

Radiotherapy

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

We demonstrate a method to estimate the concentrations of water and lipid in scattering media such as biological tissues with diffuse optical spectra acquired over the range of 900 to 1600 nm. Estimations were performed by fitting the spectra to a model of light propagation in scattering media derived from diffusion theory. To validate the method, spectra were acquired from tissue phantoms consisting of lipid and water emulsions and swine tissues ex vivo with a two-fiber probe. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI:10.1117/1.3454392]

Original language	Undefined/Unknown
Journal	Journal of Biomedical Optics
Volume	15
Issue number	3
DOIs	https://doi.org/10.1117/1.3454392
Publication status	Published - 2010

Access to Document

10.1117/1.3454392

http://hdl.handle.net/1765/33154

Cite this

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title = "Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm",

abstract = "We demonstrate a method to estimate the concentrations of water and lipid in scattering media such as biological tissues with diffuse optical spectra acquired over the range of 900 to 1600 nm. Estimations were performed by fitting the spectra to a model of light propagation in scattering media derived from diffusion theory. To validate the method, spectra were acquired from tissue phantoms consisting of lipid and water emulsions and swine tissues ex vivo with a two-fiber probe. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI:10.1117/1.3454392]",

author = "Rami Nachabe and BHW Hendriks and AE Desjardins and {van der Voort}, M and {van der Mark}, MB and Dick Sterenborg",

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T1 - Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm

AU - Nachabe, Rami

AU - Hendriks, BHW

AU - Desjardins, AE

AU - van der Voort, M

AU - van der Mark, MB

AU - Sterenborg, Dick

PY - 2010

Y1 - 2010

N2 - We demonstrate a method to estimate the concentrations of water and lipid in scattering media such as biological tissues with diffuse optical spectra acquired over the range of 900 to 1600 nm. Estimations were performed by fitting the spectra to a model of light propagation in scattering media derived from diffusion theory. To validate the method, spectra were acquired from tissue phantoms consisting of lipid and water emulsions and swine tissues ex vivo with a two-fiber probe. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI:10.1117/1.3454392]

AB - We demonstrate a method to estimate the concentrations of water and lipid in scattering media such as biological tissues with diffuse optical spectra acquired over the range of 900 to 1600 nm. Estimations were performed by fitting the spectra to a model of light propagation in scattering media derived from diffusion theory. To validate the method, spectra were acquired from tissue phantoms consisting of lipid and water emulsions and swine tissues ex vivo with a two-fiber probe. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI:10.1117/1.3454392]

U2 - 10.1117/1.3454392

DO - 10.1117/1.3454392

M3 - Article

SN - 1083-3668

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JO - Journal of Biomedical Optics

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