Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm

Rami Nachabe, BHW Hendriks, AE Desjardins, M van der Voort, MB van der Mark, Dick Sterenborg

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Abstract

We demonstrate a method to estimate the concentrations of water and lipid in scattering media such as biological tissues with diffuse optical spectra acquired over the range of 900 to 1600 nm. Estimations were performed by fitting the spectra to a model of light propagation in scattering media derived from diffusion theory. To validate the method, spectra were acquired from tissue phantoms consisting of lipid and water emulsions and swine tissues ex vivo with a two-fiber probe. (C) 2010 Society of Photo-Optical Instrumentation Engineers. [DOI:10.1117/1.3454392]
Original languageUndefined/Unknown
JournalJournal of Biomedical Optics
Volume15
Issue number3
DOIs
Publication statusPublished - 2010

Research programs

  • EMC MM-03-32-09

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