Ethnic differences in participation in prenatal screening for Down syndrome: A register-based study

Mirjam Fransen, Marleen Schoonen, Johan Mackenbach, Eric Steegers, Harry de Koning, JAM Laudy, Robert-Jan Galjaard, Caspar Looman, Marie-louise Bot, Hajo Wildschut

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Objective To assess ethnic differences in participation in prenatal screening for Down syndrome it the Netherlands Methods Participation in prenatal screening was assessed for the period 1 January 2009 to 1 July 2009 in a defined postal code area in the southwest of the Netherlands Data on ethnic origin. socio-economic background and age of participants in prenatal screening were obtained from the Medical Diagnostic Centre and the Department of Clinical Genetics Population data were obtained from Statistics Netherlands. Logistic regression models were used to assess ethnic differences in participation. adjusted for socio-economic and age differences Results The overall participation in prenatal screening was 3865 out of 15093 (26%) Participation was 28% among Dutch women. 15% among those from Turkish ethnic origin, 8% among those from North-African origin. 15% among those from Aruban/Antillean origin and 26% among women front Surinamese origin Conclusions Compared to Dutch women, those front Turkish, North-African. Aruban/Antillean and other non-Western ethnic origin were less likely to participate in screening It was unexpected that women from Surinamese origin equally participated It should be further investigated to what extent participation and non-participation in these various ethnic groups was based on informed decision-making Copyright (C) 2010 John Wiley & Sons, Ltd
Original languageUndefined/Unknown
Pages (from-to)988-994
Number of pages7
JournalPrenatal Diagnosis
Issue number10
Publication statusPublished - 2010

Research programs

  • EMC MGC-02-52-01-A
  • EMC MGC-02-96-01
  • EMC NIHES-02-65-01

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