European Association of Urology Guidelines on Testicular Cancer: 2023 Update

Anna Patrikidou, Walter Cazzaniga, Daniel Berney, Joost Boormans, Isabel de Angst, Domenico Di Nardo, Christian Fankhauser, Stefanie Fischer, Carmen Gravina, Hendrik Gremmels, Axel Heidenreich, Florian Janisch, Ricardo Leão, Nicola Nicolai, Christoph Oing, Jan Oldenburg, Robert Shepherd, Torgrim Tandstad, David Nicol*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

43 Citations (Scopus)


Context: Each year the European Association of Urology (EAU) produce a document based on the most recent evidence on the diagnosis, therapy, and follow-up of testicular cancer (TC). Objective: To represent a summarised version of the EAU guidelines on TC for 2023 with a focus on key changes in the 2023 update. Evidence acquisition: A multidisciplinary panel of TC experts, comprising urologists, medical and radiation oncologists, and pathologists, reviewed the results from a structured literature search to compile the guidelines document. Each recommendation in the guidelines was assigned a strength rating. Evidence synthesis: For the 2023 EAU guidelines on TC, a review and restructure were undertaken. The key changes incorporated in the 2023 update include: new supporting text regarding venous thromboembolism prophylaxis in males with metastatic germ cell tumours receiving chemotherapy; quality of life after treatment; an update of the histological classifications and inclusion of the World Health Organization 2022 pathological classification; inclusion of the revalidation of the 1997 International Germ Cell Cancer Collaborative Group prognostic risk factors; and a new section covering oncology treatment protocols. Conclusions: The 2023 version of the EAU guidelines on TC include the highest available scientific evidence to standardise the management of TC. Better stratification and optimisation of treatment modalities will continue to improve the high survival rates for patients with TC. Patient summary: This article presents a summary of the European Association of Urology guidelines on testicular cancer published in 2023 and includes the latest recommendations for management of this disease. The guidelines are a valuable resource that may help patients in understanding treatment recommendations.

Original languageEnglish
Pages (from-to)289-301
Number of pages13
JournalEuropean Urology
Issue number3
Early online date12 May 2023
Publication statusPublished - Sept 2023

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© 2023


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