Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

XQ Jian; CL Satizabal; AV Smith; K Wittfeld; JC Bis; JA Smith; FC Hsu; K Nho; E Hofer; SP Hagenaars; PA Nyquist; A Mishra; Hieab Adams; S Li; A Teumer; W Zhao; BI Freedman; Y Saba; LR Yanek; G Chauhan; MA van Buchem; M Cushman; NA Royle; RN Bryan; Wiro Niessen; BG Windham; AL DeStefano; M Habes; SR Heckbert; ND Palmer; CE Lewis; G Eiriksdottir; P Maillard; RA Mathias; G Homuth; MD Valdes-Hernandez; J Divers; AS Beiser; S Langner; KM Rice; ME Bastin; Q Yang; JA Maldjian; JM Starr; S Sidney; SL Risacher; André Uitterlinden; VG Gudnason; M Nauck; JI Rotter; PJ Schreiner; E Boerwinkle; Cornelia Duijn; B Mazoyer; B von Sarnowski; RF Gottesman; D Levy; S Sigurdsson; Meike Vernooij; ST Turner; R Schmidt; JM Wardlaw; BM Psaty; TH Mosley; CS DeCarli; AJ Saykin; DW Bowden; DM Becker; IJ Deary; H Schmidt; SLR Kardia; Arfan Ikram; S Debette; HJ Grabe; WT Longstreth; S Seshadri; LJ Launer; M Fornage

doi:10.1161/strokeaha.118.020689

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

XQ Jian
, CL Satizabal
, AV Smith
, K Wittfeld
, JC Bis
, JA Smith
, FC Hsu
, K Nho
, E Hofer
, SP Hagenaars
, PA Nyquist
, A Mishra
, Hieab Adams
, S Li
, A Teumer
, W Zhao
, BI Freedman
, Y Saba
, LR Yanek
, G Chauhan

MA van Buchem, M Cushman, NA Royle, RN Bryan, Wiro Niessen, BG Windham, AL DeStefano, M Habes, SR Heckbert, ND Palmer, CE Lewis, G Eiriksdottir, P Maillard, RA Mathias, G Homuth, MD Valdes-Hernandez, J Divers, AS Beiser, S Langner, KM Rice, ME Bastin, Q Yang, JA Maldjian, JM Starr, S Sidney, SL Risacher, André Uitterlinden, VG Gudnason, M Nauck, JI Rotter, PJ Schreiner, E Boerwinkle, Cornelia Duijn, B Mazoyer, B von Sarnowski, RF Gottesman, D Levy, S Sigurdsson, Meike Vernooij, ST Turner, R Schmidt, JM Wardlaw, BM Psaty, TH Mosley, CS DeCarli, AJ Saykin, DW Bowden, DM Becker, IJ Deary, H Schmidt, SLR Kardia, Arfan Ikram, S Debette, HJ Grabe, WT Longstreth, S Seshadri, LJ Launer, M Fornage

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

20 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	1812-1819
Number of pages	8
Journal	Journal of the American Heart Association
Volume	49
Issue number	8
DOIs	https://doi.org/10.1161/strokeaha.118.020689
Publication status	Published - 2018

Research programs

EMC MM-01-39-09-A
EMC NIHES-01-64-02
EMC NIHES-03-30-02
EMC NIHES-03-30-03

Access to Document

10.1161/strokeaha.118.020689

http://hdl.handle.net/1765/111637

Cite this

Jian, XQ., Satizabal, CL., Smith, AV., Wittfeld, K., Bis, JC., Smith, JA., Hsu, FC., Nho, K., Hofer, E., Hagenaars, SP., Nyquist, PA., Mishra, A., Adams, H., Li, S., Teumer, A., Zhao, W., Freedman, BI., Saba, Y., Yanek, LR., ... Fornage, M. (2018). Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging. Journal of the American Heart Association, 49(8), 1812-1819. https://doi.org/10.1161/strokeaha.118.020689

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author = "XQ Jian and CL Satizabal and AV Smith and K Wittfeld and JC Bis and JA Smith and FC Hsu and K Nho and E Hofer and SP Hagenaars and PA Nyquist and A Mishra and Hieab Adams and S Li and A Teumer and W Zhao and BI Freedman and Y Saba and LR Yanek and G Chauhan and \{van Buchem\}, MA and M Cushman and NA Royle and RN Bryan and Wiro Niessen and BG Windham and AL DeStefano and M Habes and SR Heckbert and ND Palmer and CE Lewis and G Eiriksdottir and P Maillard and RA Mathias and G Homuth and MD Valdes-Hernandez and J Divers and AS Beiser and S Langner and KM Rice and ME Bastin and Q Yang and JA Maldjian and JM Starr and S Sidney and SL Risacher and Andr{\'e} Uitterlinden and VG Gudnason and M Nauck and JI Rotter and PJ Schreiner and E Boerwinkle and Cornelia Duijn and B Mazoyer and \{von Sarnowski\}, B and RF Gottesman and D Levy and S Sigurdsson and Meike Vernooij and ST Turner and R Schmidt and JM Wardlaw and BM Psaty and TH Mosley and CS DeCarli and AJ Saykin and DW Bowden and DM Becker and IJ Deary and H Schmidt and SLR Kardia and Arfan Ikram and S Debette and HJ Grabe and WT Longstreth and S Seshadri and LJ Launer and M Fornage",

year = "2018",

doi = "10.1161/strokeaha.118.020689",

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journal = "Journal of the American Heart Association",

issn = "0039-2499",

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Jian, XQ, Satizabal, CL, Smith, AV, Wittfeld, K, Bis, JC, Smith, JA, Hsu, FC, Nho, K, Hofer, E, Hagenaars, SP, Nyquist, PA, Mishra, A, Adams, H, Li, S, Teumer, A, Zhao, W, Freedman, BI, Saba, Y, Yanek, LR, Chauhan, G, van Buchem, MA, Cushman, M, Royle, NA, Bryan, RN, Niessen, W, Windham, BG, DeStefano, AL, Habes, M, Heckbert, SR, Palmer, ND, Lewis, CE, Eiriksdottir, G, Maillard, P, Mathias, RA, Homuth, G, Valdes-Hernandez, MD, Divers, J, Beiser, AS, Langner, S, Rice, KM, Bastin, ME, Yang, Q, Maldjian, JA, Starr, JM, Sidney, S, Risacher, SL, Uitterlinden, A, Gudnason, VG, Nauck, M, Rotter, JI, Schreiner, PJ, Boerwinkle, E, Duijn, C, Mazoyer, B, von Sarnowski, B, Gottesman, RF, Levy, D, Sigurdsson, S, Vernooij, M, Turner, ST, Schmidt, R, Wardlaw, JM, Psaty, BM, Mosley, TH, DeCarli, CS, Saykin, AJ, Bowden, DW, Becker, DM, Deary, IJ, Schmidt, H, Kardia, SLR, Ikram, A, Debette, S, Grabe, HJ, Longstreth, WT, Seshadri, S, Launer, LJ & Fornage, M 2018, 'Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging', Journal of the American Heart Association, vol. 49, no. 8, pp. 1812-1819. https://doi.org/10.1161/strokeaha.118.020689

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T1 - Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

AU - Jian, XQ

AU - Satizabal, CL

AU - Smith, AV

AU - Wittfeld, K

AU - Bis, JC

AU - Smith, JA

AU - Hsu, FC

AU - Nho, K

AU - Hofer, E

AU - Hagenaars, SP

AU - Nyquist, PA

AU - Mishra, A

AU - Adams, Hieab

AU - Li, S

AU - Teumer, A

AU - Zhao, W

AU - Freedman, BI

AU - Saba, Y

AU - Yanek, LR

AU - Chauhan, G

AU - van Buchem, MA

AU - Cushman, M

AU - Royle, NA

AU - Bryan, RN

AU - Niessen, Wiro

AU - Windham, BG

AU - DeStefano, AL

AU - Habes, M

AU - Heckbert, SR

AU - Palmer, ND

AU - Lewis, CE

AU - Eiriksdottir, G

AU - Maillard, P

AU - Mathias, RA

AU - Homuth, G

AU - Valdes-Hernandez, MD

AU - Divers, J

AU - Beiser, AS

AU - Langner, S

AU - Rice, KM

AU - Bastin, ME

AU - Yang, Q

AU - Maldjian, JA

AU - Starr, JM

AU - Sidney, S

AU - Risacher, SL

AU - Uitterlinden, André

AU - Gudnason, VG

AU - Nauck, M

AU - Rotter, JI

AU - Schreiner, PJ

AU - Boerwinkle, E

AU - Duijn, Cornelia

AU - Mazoyer, B

AU - von Sarnowski, B

AU - Gottesman, RF

AU - Levy, D

AU - Sigurdsson, S

AU - Vernooij, Meike

AU - Turner, ST

AU - Schmidt, R

AU - Wardlaw, JM

AU - Psaty, BM

AU - Mosley, TH

AU - DeCarli, CS

AU - Saykin, AJ

AU - Bowden, DW

AU - Becker, DM

AU - Deary, IJ

AU - Schmidt, H

AU - Kardia, SLR

AU - Ikram, Arfan

AU - Debette, S

AU - Grabe, HJ

AU - Longstreth, WT

AU - Seshadri, S

AU - Launer, LJ

AU - Fornage, M

PY - 2018

Y1 - 2018

U2 - 10.1161/strokeaha.118.020689

DO - 10.1161/strokeaha.118.020689

M3 - Article

SN - 0039-2499

VL - 49

SP - 1812

EP - 1819

JO - Journal of the American Heart Association

JF - Journal of the American Heart Association

IS - 8

ER -