Expansion and chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells

Research output: Chapter/Conference proceedingChapterAcademic

Abstract

Human bone marrow-derived mesenchymal stem/stromal cells (BM-MSC) are adult multipotent progenitor cells that can be isolated from bone marrow. BM-MSCs have the ability to be expanded and differentiated into the chondrogenic lineage in vitro. Here we describe a standardized method to expand and chondrogenically differentiate human BM-MSCs, highlighting how to overcome technical challenges and indicating the most common readout parameters to evaluate the chondrogenic differentiation capacity.

Original languageEnglish
Title of host publicationOsteoporosis and Osteoarthritis
Place of Publication[S.l.]
Pages15-28
Number of pages15
Volume2221
DOIs
Publication statusPublished - 2021

Publication series

SeriesMethods in Molecular Biology
Volume2221

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