Extended Transthoracic Resection Compared with Limited Transhiatal Resection for Adenocarcinoma of the Esophagus

Jan B.F. Hulscher; Johanna W. van Sandick; Angela G.E.M. de Boer; Bas P.L. Wijnhoven; Jan G.P. Tijssen; Paul Fockens; Peep F.M. Stalmeier; Fiebo J.W. ten Kate; Herman van Dekken; Hugo Obertop; Hugo W. Tilanus; Jan J. van Lanschot

doi:10.1056/NEJMoa022343

Extended Transthoracic Resection Compared with Limited Transhiatal Resection for Adenocarcinoma of the Esophagus

Jan B.F. Hulscher
, Johanna W. van Sandick
, Angela G.E.M. de Boer
, Bas P.L. Wijnhoven
, Jan G.P. Tijssen
, Paul Fockens
, Peep F.M. Stalmeier
, Fiebo J.W. ten Kate
, Herman van Dekken
, Hugo Obertop
, Hugo W. Tilanus
, Jan J. van Lanschot

Amsterdam UMC, Locatie UvA/AMC

Research output: Contribution to journal › Article › Academic › peer-review

1496 Citations (Scopus)

Abstract

Transhiatal esophagectomy was associated with lower morbidity than transthoracic esophagectomy with extended en bloc lymphadenectomy. Although median overall, disease-free, and quality-adjusted survival did not differ statistically between the groups, there was a trend toward improved long-term survival at five years with the extended transthoracic approach.

Original language	English
Pages (from-to)	1662-1669
Number of pages	8
Journal	New England Journal of Medicine
Volume	347
Issue number	21
DOIs	https://doi.org/10.1056/NEJMoa022343
Publication status	Published - 21 Nov 2002

Research programs

EMC MM-03-24-03
EMC MM-03-47-06-A

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10.1056/NEJMoa022343

http://hdl.handle.net/1765/58453

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Hulscher, J. B. F., van Sandick, J. W., de Boer, A. G. E. M., Wijnhoven, B. P. L., Tijssen, J. G. P., Fockens, P., Stalmeier, P. F. M., ten Kate, F. J. W., van Dekken, H., Obertop, H., Tilanus, H. W., & van Lanschot, J. J. (2002). Extended Transthoracic Resection Compared with Limited Transhiatal Resection for Adenocarcinoma of the Esophagus. New England Journal of Medicine, 347(21), 1662-1669. https://doi.org/10.1056/NEJMoa022343

@article{2567213edaa2490ba9949e35dbc25758,

title = "Extended Transthoracic Resection Compared with Limited Transhiatal Resection for Adenocarcinoma of the Esophagus",

abstract = "Transhiatal esophagectomy was associated with lower morbidity than transthoracic esophagectomy with extended en bloc lymphadenectomy. Although median overall, disease-free, and quality-adjusted survival did not differ statistically between the groups, there was a trend toward improved long-term survival at five years with the extended transthoracic approach.",

author = "Hulscher, \{Jan B.F.\} and \{van Sandick\}, \{Johanna W.\} and \{de Boer\}, \{Angela G.E.M.\} and Wijnhoven, \{Bas P.L.\} and Tijssen, \{Jan G.P.\} and Paul Fockens and Stalmeier, \{Peep F.M.\} and \{ten Kate\}, \{Fiebo J.W.\} and \{van Dekken\}, Herman and Hugo Obertop and Tilanus, \{Hugo W.\} and \{van Lanschot\}, \{Jan J.\}",

year = "2002",

month = nov,

day = "21",

doi = "10.1056/NEJMoa022343",

language = "English",

volume = "347",

pages = "1662--1669",

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Hulscher, JBF, van Sandick, JW, de Boer, AGEM, Wijnhoven, BPL, Tijssen, JGP, Fockens, P, Stalmeier, PFM, ten Kate, FJW, van Dekken, H, Obertop, H, Tilanus, HW & van Lanschot, JJ 2002, 'Extended Transthoracic Resection Compared with Limited Transhiatal Resection for Adenocarcinoma of the Esophagus', New England Journal of Medicine, vol. 347, no. 21, pp. 1662-1669. https://doi.org/10.1056/NEJMoa022343

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T1 - Extended Transthoracic Resection Compared with Limited Transhiatal Resection for Adenocarcinoma of the Esophagus

AU - Hulscher, Jan B.F.

AU - van Sandick, Johanna W.

AU - de Boer, Angela G.E.M.

AU - Wijnhoven, Bas P.L.

AU - Tijssen, Jan G.P.

AU - Fockens, Paul

AU - Stalmeier, Peep F.M.

AU - ten Kate, Fiebo J.W.

AU - van Dekken, Herman

AU - Obertop, Hugo

AU - Tilanus, Hugo W.

AU - van Lanschot, Jan J.

PY - 2002/11/21

Y1 - 2002/11/21

N2 - Transhiatal esophagectomy was associated with lower morbidity than transthoracic esophagectomy with extended en bloc lymphadenectomy. Although median overall, disease-free, and quality-adjusted survival did not differ statistically between the groups, there was a trend toward improved long-term survival at five years with the extended transthoracic approach.

AB - Transhiatal esophagectomy was associated with lower morbidity than transthoracic esophagectomy with extended en bloc lymphadenectomy. Although median overall, disease-free, and quality-adjusted survival did not differ statistically between the groups, there was a trend toward improved long-term survival at five years with the extended transthoracic approach.

U2 - 10.1056/NEJMoa022343

DO - 10.1056/NEJMoa022343

M3 - Article

C2 - 12444180

SN - 0028-4793

VL - 347

SP - 1662

EP - 1669

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 21

ER -

Extended Transthoracic Resection Compared with Limited Transhiatal Resection for Adenocarcinoma of the Esophagus

Abstract

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