Factors associated with posttraumatic stress symptoms in a prospective cohort of patients after abdominal sepsis: A nomogram

Kimberly R. Boer; O. Van Ruler; Arnold A.P. Van Emmerik; Mirjam A. Sprangers; Sophia E. De Rooij; Margreeth B. Vroom; C. A.J.M. De Borgie; M. A. Boermeester; Johannes B. Reitsma; O. Van Ruler; K. R. Boer; Johannes  B. Reitsma; C. W. Mahler; E. A. Reuland; J. W.O. Van Till; B. C. Opmeer; P. M.M. Bossuyt; M. J. Schultz; M. A. Sprangers; H. Obertop; D. J. Gouma; C. A.J.M. De Borgie; M. A. Boermeester; E. P. Steller; P. Tanis; H. Hart; M. F. Gerhards; M. Guijt; H. M. Oudemans; K. Bosscha; E. Ritchie; M. Vermeer; P. W. De Graaf; B. Van Etten; C. Haazer; E. Salm; B. Lamme; E. J. Hesselink; H. Rommes; R. J. Oostenbroek; L. Te Velde; G. Govaert; H. H. Ponssen; H. G. Gooszen; M. K. Dinkelman; L. P.H. Leenen; E. G.J.M. Pierik; K. W.W. Lansink; J. Bakker

doi:10.1007/s00134-007-0941-3

Factors associated with posttraumatic stress symptoms in a prospective cohort of patients after abdominal sepsis: A nomogram

Kimberly R. Boer, O. Van Ruler, Arnold A.P. Van Emmerik, Mirjam A. Sprangers, Sophia E. De Rooij, Margreeth B. Vroom, C. A.J.M. De Borgie, M. A. Boermeester, Johannes B. Reitsma, O. Van Ruler, K. R. Boer, Johannes B. Reitsma^*, C. W. Mahler, E. A. Reuland, J. W.O. Van Till, B. C. Opmeer, P. M.M. Bossuyt, M. J. Schultz, M. A. Sprangers, H. ObertopD. J. Gouma, C. A.J.M. De Borgie, M. A. Boermeester, E. P. Steller, P. Tanis, H. Hart, M. F. Gerhards, M. Guijt, H. M. Oudemans, K. Bosscha, E. Ritchie, M. Vermeer, P. W. De Graaf, B. Van Etten, C. Haazer, E. Salm, B. Lamme, E. J. Hesselink, H. Rommes, R. J. Oostenbroek, L. Te Velde, G. Govaert, H. H. Ponssen, H. G. Gooszen, M. K. Dinkelman, L. P.H. Leenen, E. G.J.M. Pierik, K. W.W. Lansink, J. Bakker

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Objective:

To determine to what extent patients who have survived abdominal sepsis suffer from symptoms of posttraumatic stress disorder (PTSD) and depression, and to identify potential risk factors for PTSD symptoms.

Design and setting:

PTSD and depression symptoms were measured using the Impact of Events Scale-Revised (IES-R), the Post-Traumatic Symptom Scale 10 (PTSS-10) and the Beck Depression Inventory II (BDI-II).

Patients and participants:

A total of 135 peritonitis patients were eligible for this study, of whom 107 (80%) patients completed the questionnaire. The median APACHE-II score was 14 (range 12-16), and 89% were admitted to the ICU.

Measurements and results:

The proportion of patients with "moderate" PTSD symptom scores was 28% (95% CI 20-37), whilst 10% (95% CI 6-17) of patients had "high" PTSD symptom scores. Only 5% (95% CI 2-12) of the patients expressed severe depression symptoms. Factors associated with increased PTSD symptoms in a multivariate ordinal regression model were younger age (0.74 per 10 years older, p = 0.082), length of ICU stay (OR = 1.4 per doubling of duration, p = 0.003) and having some (OR = 4.9, p = 0.06) or many (OR = 55.5, p < 0.001) traumatic memories of the ICU or hospital stay.

Conclusion:

As many as 38% of patients after abdominal sepsis report elevated levels of PTSD symptoms on at least one of the questionnaires. Our nomogram may assist in identifying patients at increased risk for developing symptoms of PTSD.

Original language	English
Pages (from-to)	664-674
Number of pages	11
Journal	Intensive Care Medicine
Volume	34
Issue number	4
DOIs	https://doi.org/10.1007/s00134-007-0941-3
Publication status	Published - Apr 2008

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Factors associated with posttraumatic stress symptoms in a prospective cohort of patients after abdominal sepsisFinal published version, 317 KBLicence: CC BY-NC

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Boer, K. R., Van Ruler, O., Van Emmerik, A. A. P., Sprangers, M. A., De Rooij, S. E., Vroom, M. B., De Borgie, C. A. J. M., Boermeester, M. A., Reitsma, J. B., Van Ruler, O., Boer, K. R., Reitsma, J. B., Mahler, C. W., Reuland, E. A., Van Till, J. W. O., Opmeer, B. C., Bossuyt, P. M. M., Schultz, M. J., Sprangers, M. A., ... Bakker, J. (2008). Factors associated with posttraumatic stress symptoms in a prospective cohort of patients after abdominal sepsis: A nomogram. Intensive Care Medicine, 34(4), 664-674. https://doi.org/10.1007/s00134-007-0941-3

@article{c5036fd6d53b4cd8b1e4c0cb9330d613,

title = "Factors associated with posttraumatic stress symptoms in a prospective cohort of patients after abdominal sepsis: A nomogram",

abstract = "Objective: To determine to what extent patients who have survived abdominal sepsis suffer from symptoms of posttraumatic stress disorder (PTSD) and depression, and to identify potential risk factors for PTSD symptoms. Design and setting: PTSD and depression symptoms were measured using the Impact of Events Scale-Revised (IES-R), the Post-Traumatic Symptom Scale 10 (PTSS-10) and the Beck Depression Inventory II (BDI-II). Patients and participants: A total of 135 peritonitis patients were eligible for this study, of whom 107 (80\%) patients completed the questionnaire. The median APACHE-II score was 14 (range 12-16), and 89\% were admitted to the ICU.Measurements and results: The proportion of patients with {"}moderate{"} PTSD symptom scores was 28\% (95\% CI 20-37), whilst 10\% (95\% CI 6-17) of patients had {"}high{"} PTSD symptom scores. Only 5\% (95\% CI 2-12) of the patients expressed severe depression symptoms. Factors associated with increased PTSD symptoms in a multivariate ordinal regression model were younger age (0.74 per 10 years older, p = 0.082), length of ICU stay (OR = 1.4 per doubling of duration, p = 0.003) and having some (OR = 4.9, p = 0.06) or many (OR = 55.5, p < 0.001) traumatic memories of the ICU or hospital stay. Conclusion: As many as 38\% of patients after abdominal sepsis report elevated levels of PTSD symptoms on at least one of the questionnaires. Our nomogram may assist in identifying patients at increased risk for developing symptoms of PTSD.",

author = "Boer, \{Kimberly R.\} and \{Van Ruler\}, O. and \{Van Emmerik\}, \{Arnold A.P.\} and Sprangers, \{Mirjam A.\} and \{De Rooij\}, \{Sophia E.\} and Vroom, \{Margreeth B.\} and \{De Borgie\}, \{C. A.J.M.\} and Boermeester, \{M. A.\} and Reitsma, \{Johannes B.\} and \{Van Ruler\}, O. and Boer, \{K. R.\} and Reitsma, \{Johannes B.\} and Mahler, \{C. W.\} and Reuland, \{E. A.\} and \{Van Till\}, \{J. W.O.\} and Opmeer, \{B. C.\} and Bossuyt, \{P. M.M.\} and Schultz, \{M. J.\} and Sprangers, \{M. A.\} and H. Obertop and Gouma, \{D. J.\} and \{De Borgie\}, \{C. A.J.M.\} and Boermeester, \{M. A.\} and Steller, \{E. P.\} and P. Tanis and H. Hart and Gerhards, \{M. F.\} and M. Guijt and Oudemans, \{H. M.\} and K. Bosscha and E. Ritchie and M. Vermeer and \{De Graaf\}, \{P. W.\} and \{Van Etten\}, B. and C. Haazer and E. Salm and B. Lamme and Hesselink, \{E. J.\} and H. Rommes and Oostenbroek, \{R. J.\} and \{Te Velde\}, L. and G. Govaert and Ponssen, \{H. H.\} and Gooszen, \{H. G.\} and Dinkelman, \{M. K.\} and Leenen, \{L. P.H.\} and Pierik, \{E. G.J.M.\} and Lansink, \{K. W.W.\} and J. Bakker",

year = "2008",

month = apr,

doi = "10.1007/s00134-007-0941-3",

language = "English",

volume = "34",

pages = "664--674",

journal = "Intensive Care Medicine",

issn = "0342-4642",

publisher = "Springer Science+Business Media",

number = "4",

}

Boer, KR, Van Ruler, O, Van Emmerik, AAP, Sprangers, MA, De Rooij, SE, Vroom, MB, De Borgie, CAJM, Boermeester, MA, Reitsma, JB, Van Ruler, O, Boer, KR, Reitsma, JB, Mahler, CW, Reuland, EA, Van Till, JWO, Opmeer, BC, Bossuyt, PMM, Schultz, MJ, Sprangers, MA, Obertop, H, Gouma, DJ, De Borgie, CAJM, Boermeester, MA, Steller, EP, Tanis, P, Hart, H, Gerhards, MF, Guijt, M, Oudemans, HM, Bosscha, K, Ritchie, E, Vermeer, M, De Graaf, PW, Van Etten, B, Haazer, C, Salm, E, Lamme, B, Hesselink, EJ, Rommes, H, Oostenbroek, RJ, Te Velde, L, Govaert, G, Ponssen, HH, Gooszen, HG, Dinkelman, MK, Leenen, LPH, Pierik, EGJM, Lansink, KWW & Bakker, J 2008, 'Factors associated with posttraumatic stress symptoms in a prospective cohort of patients after abdominal sepsis: A nomogram', Intensive Care Medicine, vol. 34, no. 4, pp. 664-674. https://doi.org/10.1007/s00134-007-0941-3

TY - JOUR

T1 - Factors associated with posttraumatic stress symptoms in a prospective cohort of patients after abdominal sepsis

T2 - A nomogram

AU - Boer, Kimberly R.

AU - Van Ruler, O.

AU - Van Emmerik, Arnold A.P.

AU - Sprangers, Mirjam A.

AU - De Rooij, Sophia E.

AU - Vroom, Margreeth B.

AU - De Borgie, C. A.J.M.

AU - Boermeester, M. A.

AU - Reitsma, Johannes B.

AU - Van Ruler, O.

AU - Boer, K. R.

AU - Reitsma, Johannes B.

AU - Mahler, C. W.

AU - Reuland, E. A.

AU - Van Till, J. W.O.

AU - Opmeer, B. C.

AU - Bossuyt, P. M.M.

AU - Schultz, M. J.

AU - Sprangers, M. A.

AU - Obertop, H.

AU - Gouma, D. J.

AU - De Borgie, C. A.J.M.

AU - Boermeester, M. A.

AU - Steller, E. P.

AU - Tanis, P.

AU - Hart, H.

AU - Gerhards, M. F.

AU - Guijt, M.

AU - Oudemans, H. M.

AU - Bosscha, K.

AU - Ritchie, E.

AU - Vermeer, M.

AU - De Graaf, P. W.

AU - Van Etten, B.

AU - Haazer, C.

AU - Salm, E.

AU - Lamme, B.

AU - Hesselink, E. J.

AU - Rommes, H.

AU - Oostenbroek, R. J.

AU - Te Velde, L.

AU - Govaert, G.

AU - Ponssen, H. H.

AU - Gooszen, H. G.

AU - Dinkelman, M. K.

AU - Leenen, L. P.H.

AU - Pierik, E. G.J.M.

AU - Lansink, K. W.W.

AU - Bakker, J.

PY - 2008/4

Y1 - 2008/4

N2 - Objective: To determine to what extent patients who have survived abdominal sepsis suffer from symptoms of posttraumatic stress disorder (PTSD) and depression, and to identify potential risk factors for PTSD symptoms. Design and setting: PTSD and depression symptoms were measured using the Impact of Events Scale-Revised (IES-R), the Post-Traumatic Symptom Scale 10 (PTSS-10) and the Beck Depression Inventory II (BDI-II). Patients and participants: A total of 135 peritonitis patients were eligible for this study, of whom 107 (80%) patients completed the questionnaire. The median APACHE-II score was 14 (range 12-16), and 89% were admitted to the ICU.Measurements and results: The proportion of patients with "moderate" PTSD symptom scores was 28% (95% CI 20-37), whilst 10% (95% CI 6-17) of patients had "high" PTSD symptom scores. Only 5% (95% CI 2-12) of the patients expressed severe depression symptoms. Factors associated with increased PTSD symptoms in a multivariate ordinal regression model were younger age (0.74 per 10 years older, p = 0.082), length of ICU stay (OR = 1.4 per doubling of duration, p = 0.003) and having some (OR = 4.9, p = 0.06) or many (OR = 55.5, p < 0.001) traumatic memories of the ICU or hospital stay. Conclusion: As many as 38% of patients after abdominal sepsis report elevated levels of PTSD symptoms on at least one of the questionnaires. Our nomogram may assist in identifying patients at increased risk for developing symptoms of PTSD.

AB - Objective: To determine to what extent patients who have survived abdominal sepsis suffer from symptoms of posttraumatic stress disorder (PTSD) and depression, and to identify potential risk factors for PTSD symptoms. Design and setting: PTSD and depression symptoms were measured using the Impact of Events Scale-Revised (IES-R), the Post-Traumatic Symptom Scale 10 (PTSS-10) and the Beck Depression Inventory II (BDI-II). Patients and participants: A total of 135 peritonitis patients were eligible for this study, of whom 107 (80%) patients completed the questionnaire. The median APACHE-II score was 14 (range 12-16), and 89% were admitted to the ICU.Measurements and results: The proportion of patients with "moderate" PTSD symptom scores was 28% (95% CI 20-37), whilst 10% (95% CI 6-17) of patients had "high" PTSD symptom scores. Only 5% (95% CI 2-12) of the patients expressed severe depression symptoms. Factors associated with increased PTSD symptoms in a multivariate ordinal regression model were younger age (0.74 per 10 years older, p = 0.082), length of ICU stay (OR = 1.4 per doubling of duration, p = 0.003) and having some (OR = 4.9, p = 0.06) or many (OR = 55.5, p < 0.001) traumatic memories of the ICU or hospital stay. Conclusion: As many as 38% of patients after abdominal sepsis report elevated levels of PTSD symptoms on at least one of the questionnaires. Our nomogram may assist in identifying patients at increased risk for developing symptoms of PTSD.

UR - https://www.scopus.com/pages/publications/43349093088

U2 - 10.1007/s00134-007-0941-3

DO - 10.1007/s00134-007-0941-3

M3 - Article

C2 - 18197398

AN - SCOPUS:43349093088

SN - 0342-4642

VL - 34

SP - 664

EP - 674

JO - Intensive Care Medicine

JF - Intensive Care Medicine

IS - 4

ER -

Factors associated with posttraumatic stress symptoms in a prospective cohort of patients after abdominal sepsis: A nomogram

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