Factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT)

Lisanne van Prooyen Schuurman; Karuna van der Meij; Dutch NIPT Consortium; Nicolien van Ravesteyn; Neeltje Crombag; Janneke Gitsels-van der Wal; Caroline Kooij; Linda Martin; Ingrid Peters; Marike Polak; Elsbeth Van Vliet-Lachotzki; Robert-Jan Galjaard; Lidewij Henneman

doi:10.1002/pd.6242

Factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT)

Lisanne van Prooyen Schuurman
, Karuna van der Meij
, Dutch NIPT Consortium
, Nicolien van Ravesteyn
, Neeltje Crombag
, Janneke Gitsels-van der Wal
, Caroline Kooij
, Linda Martin
, Ingrid Peters
, Marike Polak
, Elsbeth Van Vliet-Lachotzki
, Robert-Jan Galjaard
, Lidewij Henneman^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

8 Citations (Scopus)

127 Downloads (Pure)

Abstract

Objective To investigate factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT). Method A questionnaire study was conducted among 219 pregnant women in the Netherlands who had declined prenatal screening with NIPT (TRIDENT-2 study). Respondents were selectively recruited from three hospitals and 19 midwifery practices, primarily located in or near socioeconomically disadvantaged neighborhoods. 44.3% of the respondents were of non-Western ethnic origin and 64.4% were religious. Results Most respondents (77.2%) found the decision to decline NIPT easy to make, and 59.8% had already made the decision before information about NIPT was offered. These respondents were more often religious, multigravida, and had adequate health literacy. The main reasons to decline NIPT were "I would never terminate my pregnancy" (57.1%) and "every child is welcome" (56.2%). For 16.9% of respondents, the out-of-pocket costs (175 euros) played a role in the decision, and the women in this group were more often nonreligious, primigravida, and had inadequate health literacy. Conclusion The primary factors involved in the decision to decline NIPT were related to personal values and beliefs, consistent with autonomous choice. Out-of-pocket costs of NIPT hinder equal access for some pregnant women.

Original language	English
Pages (from-to)	467-476
Number of pages	10
Journal	Prenatal Diagnosis
Volume	43
Issue number	4
Early online date	23 Sept 2022
DOIs	https://doi.org/10.1002/pd.6242
Publication status	Published - Apr 2023

Bibliographical note

Funding Information:
The authors would like to thank all participating women, midwifery practices, and hospitals for their contribution to this study. Moreover, we thank all who have contributed to the design and execution of this study, including Inssaf El Hammoud, Hafsa Ouaddouh, Ineke van den Berg, Marjolijn van Leeuwen, and Loes van der Wees. Quinty Küsters, Monique Reijn, Bente van Gool, Ester Verhoeven, and Nadine Doedens are acknowledged for administering the questionnaires. This study is supported by a grant from the Netherlands Organization for Health Research and Development (ZonMw) No. 543002001.

Funding Information:
This study is supported by a grant from the Netherlands Organization for Health Research and Development (ZonMw) No. 543002001.

Publisher Copyright:
© 2022 The Authors. Prenatal Diagnosis published by John Wiley & Sons Ltd.

Access to Document

10.1002/pd.6242Licence: CC BY-NC-ND

Factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT)Final published version, 426 KBLicence: CC BY-NC-ND

Cite this

Schuurman, L. V. P., van der Meij, K., Dutch NIPT Consortium, van Ravesteyn, N., Crombag, N., Gitsels-van der Wal, J., Kooij, C., Martin, L., Peters, I., Polak, M., Van Vliet-Lachotzki, E., Galjaard, R.-J., & Henneman, L. (2023). Factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT). Prenatal Diagnosis, 43(4), 467-476. https://doi.org/10.1002/pd.6242

@article{4d89a530782e47249ac859a4accee1a6,

title = "Factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT)",

abstract = "Objective To investigate factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT). Method A questionnaire study was conducted among 219 pregnant women in the Netherlands who had declined prenatal screening with NIPT (TRIDENT-2 study). Respondents were selectively recruited from three hospitals and 19 midwifery practices, primarily located in or near socioeconomically disadvantaged neighborhoods. 44.3\% of the respondents were of non-Western ethnic origin and 64.4\% were religious. Results Most respondents (77.2\%) found the decision to decline NIPT easy to make, and 59.8\% had already made the decision before information about NIPT was offered. These respondents were more often religious, multigravida, and had adequate health literacy. The main reasons to decline NIPT were {"}I would never terminate my pregnancy{"} (57.1\%) and {"}every child is welcome{"} (56.2\%). For 16.9\% of respondents, the out-of-pocket costs (175 euros) played a role in the decision, and the women in this group were more often nonreligious, primigravida, and had inadequate health literacy. Conclusion The primary factors involved in the decision to decline NIPT were related to personal values and beliefs, consistent with autonomous choice. Out-of-pocket costs of NIPT hinder equal access for some pregnant women.",

author = "Schuurman, \{Lisanne van Prooyen\} and \{van der Meij\}, Karuna and \{Dutch NIPT Consortium\} and \{van Ravesteyn\}, Nicolien and Neeltje Crombag and \{Gitsels-van der Wal\}, Janneke and Caroline Kooij and Linda Martin and Ingrid Peters and Marike Polak and \{Van Vliet-Lachotzki\}, Elsbeth and Robert-Jan Galjaard and Lidewij Henneman",

note = "Funding Information: The authors would like to thank all participating women, midwifery practices, and hospitals for their contribution to this study. Moreover, we thank all who have contributed to the design and execution of this study, including Inssaf El Hammoud, Hafsa Ouaddouh, Ineke van den Berg, Marjolijn van Leeuwen, and Loes van der Wees. Quinty K{\"u}sters, Monique Reijn, Bente van Gool, Ester Verhoeven, and Nadine Doedens are acknowledged for administering the questionnaires. This study is supported by a grant from the Netherlands Organization for Health Research and Development (ZonMw) No. 543002001. Funding Information: This study is supported by a grant from the Netherlands Organization for Health Research and Development (ZonMw) No. 543002001. Publisher Copyright: {\textcopyright} 2022 The Authors. Prenatal Diagnosis published by John Wiley \& Sons Ltd.",

year = "2023",

month = apr,

doi = "10.1002/pd.6242",

language = "English",

volume = "43",

pages = "467--476",

journal = "Prenatal Diagnosis",

issn = "0197-3851",

publisher = "John Wiley \& Sons Ltd.",

number = "4",

}

Schuurman, LVP, van der Meij, K, Dutch NIPT Consortium, van Ravesteyn, N, Crombag, N, Gitsels-van der Wal, J, Kooij, C, Martin, L, Peters, I , Polak, M, Van Vliet-Lachotzki, E, Galjaard, R-J & Henneman, L 2023, 'Factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT)', Prenatal Diagnosis, vol. 43, no. 4, pp. 467-476. https://doi.org/10.1002/pd.6242

TY - JOUR

T1 - Factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT)

AU - Schuurman, Lisanne van Prooyen

AU - van der Meij, Karuna

AU - Dutch NIPT Consortium

AU - van Ravesteyn, Nicolien

AU - Crombag, Neeltje

AU - Gitsels-van der Wal, Janneke

AU - Kooij, Caroline

AU - Martin, Linda

AU - Peters, Ingrid

AU - Polak, Marike

AU - Van Vliet-Lachotzki, Elsbeth

AU - Galjaard, Robert-Jan

AU - Henneman, Lidewij

N1 - Funding Information: The authors would like to thank all participating women, midwifery practices, and hospitals for their contribution to this study. Moreover, we thank all who have contributed to the design and execution of this study, including Inssaf El Hammoud, Hafsa Ouaddouh, Ineke van den Berg, Marjolijn van Leeuwen, and Loes van der Wees. Quinty Küsters, Monique Reijn, Bente van Gool, Ester Verhoeven, and Nadine Doedens are acknowledged for administering the questionnaires. This study is supported by a grant from the Netherlands Organization for Health Research and Development (ZonMw) No. 543002001. Funding Information: This study is supported by a grant from the Netherlands Organization for Health Research and Development (ZonMw) No. 543002001. Publisher Copyright: © 2022 The Authors. Prenatal Diagnosis published by John Wiley & Sons Ltd.

PY - 2023/4

Y1 - 2023/4

N2 - Objective To investigate factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT). Method A questionnaire study was conducted among 219 pregnant women in the Netherlands who had declined prenatal screening with NIPT (TRIDENT-2 study). Respondents were selectively recruited from three hospitals and 19 midwifery practices, primarily located in or near socioeconomically disadvantaged neighborhoods. 44.3% of the respondents were of non-Western ethnic origin and 64.4% were religious. Results Most respondents (77.2%) found the decision to decline NIPT easy to make, and 59.8% had already made the decision before information about NIPT was offered. These respondents were more often religious, multigravida, and had adequate health literacy. The main reasons to decline NIPT were "I would never terminate my pregnancy" (57.1%) and "every child is welcome" (56.2%). For 16.9% of respondents, the out-of-pocket costs (175 euros) played a role in the decision, and the women in this group were more often nonreligious, primigravida, and had inadequate health literacy. Conclusion The primary factors involved in the decision to decline NIPT were related to personal values and beliefs, consistent with autonomous choice. Out-of-pocket costs of NIPT hinder equal access for some pregnant women.

AB - Objective To investigate factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT). Method A questionnaire study was conducted among 219 pregnant women in the Netherlands who had declined prenatal screening with NIPT (TRIDENT-2 study). Respondents were selectively recruited from three hospitals and 19 midwifery practices, primarily located in or near socioeconomically disadvantaged neighborhoods. 44.3% of the respondents were of non-Western ethnic origin and 64.4% were religious. Results Most respondents (77.2%) found the decision to decline NIPT easy to make, and 59.8% had already made the decision before information about NIPT was offered. These respondents were more often religious, multigravida, and had adequate health literacy. The main reasons to decline NIPT were "I would never terminate my pregnancy" (57.1%) and "every child is welcome" (56.2%). For 16.9% of respondents, the out-of-pocket costs (175 euros) played a role in the decision, and the women in this group were more often nonreligious, primigravida, and had inadequate health literacy. Conclusion The primary factors involved in the decision to decline NIPT were related to personal values and beliefs, consistent with autonomous choice. Out-of-pocket costs of NIPT hinder equal access for some pregnant women.

UR - https://www.scopus.com/pages/publications/85138701625

U2 - 10.1002/pd.6242

DO - 10.1002/pd.6242

M3 - Article

C2 - 36109868

SN - 0197-3851

VL - 43

SP - 467

EP - 476

JO - Prenatal Diagnosis

JF - Prenatal Diagnosis

IS - 4

ER -

Factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT)

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this