Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

Judith M. Boer; Maria Grazia Valsecchi; Femke M. Hormann; Željko Antić; Marketa Zaliova; Claire Schwab; Giovanni Cazzaniga; Chloé Arfeuille; Hélène Cavé; Andishe Attarbaschi; Sabine Strehl; Gabriele Escherich; Toshihiko Imamura; Kentaro Ohki; Tanja A. Grüber; Rosemary Sutton; Agata Pastorczak; Tim Lammens; Frédéric Lambert; Chi Kong Li; Enrique Carrillo de Santa Pau; Steve Hoffmann; Anja Möricke; Christine J. Harrison; Monique L. Den Boer; Paola De Lorenzo; Ronald W. Stam; Anke K. Bergmann; Rob Pieters

doi:10.1038/s41375-021-01333-y

Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

Judith M. Boer^*, Maria Grazia Valsecchi, Femke M. Hormann, Željko Antić, Marketa Zaliova, Claire Schwab, Giovanni Cazzaniga, Chloé Arfeuille, Hélène Cavé, Andishe Attarbaschi, Sabine Strehl, Gabriele Escherich, Toshihiko Imamura, Kentaro Ohki, Tanja A. Grüber, Rosemary Sutton, Agata Pastorczak, Tim Lammens, Frédéric Lambert, Chi Kong LiEnrique Carrillo de Santa Pau, Steve Hoffmann, Anja Möricke, Christine J. Harrison, Monique L. Den Boer, Paola De Lorenzo, Ronald W. Stam, Anke K. Bergmann, Rob Pieters

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

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Original language	English
Pages (from-to)	2978-2982
Number of pages	5
Journal	Leukemia
Volume	35
Issue number	10
Early online date	1 Jul 2021
DOIs	https://doi.org/10.1038/s41375-021-01333-y https://doi.org/10.1038/s41375-021-01333-y
Publication status	Published - Oct 2021

Bibliographical note

Acknowledgements:
This study was conducted on behalf of the Ponte di Legno Childhood ALL Working Group. The authors gratefully acknowledge samples and data provided by the Blood Cancer UK Childhood Leukaemia Cell Bank, the Center for Biological Resources (CRB-cancer; BB-0033-00076) of the Robert Debré Hospital, the Sydney Children’s Tumour Bank Network, the Vienna BioCenter Core Facilities (VBCF; www.viennabiocenter.org/ facilities) Next-Generation Sequencing Unit, and the Blueprint Consortium. The authors would like to thank Karin Nebral and Oskar A. Haas for providing genetic data, Georg Mann for clinical data and patient samples, Dagmar Schinnerl for bioinformatics analysis of RNA-sequencing data (Berlin-Frankfurt-Münster – Austria study group), Tomasz Szczepanski and Wojciech Mlynarski (Polish Pediatric Leukaemia and Lymphoma Study Group), Martin Schrappe and Martin Zimmermann (Berlin-Frankfurt-Münster - Germany/ Switzerland study group), Alex Hoogkamer and Valerie de Haas (Dutch Childhood Oncology Group), Udo zur Stadt (Cooperative Study Group for Childhood ALL), Benoit Brethon (Société Française de la lutte contre les Cancers et les leucémies de l’Enfant et de l’Adolescent), and Rishi Kotecha (Australian & New Zealand Childrens Hematology/ Oncology Group). This project was supported by grants from the Oncode Institute (M.L. D.B.), Stichting Kinderoncologisch Centrum Rotterdam (M.L.D.B.), KiKa Foundation (KiKa-264; J.M.B.), vzw Kinderkankerfonds (T.L.), DFG grants (BE6555/1-1 (AKB), BE6555/2-1 (A. K.B., S.H.)), Anniversary Fund of the Oesterreichische Nationalbank (OeNB 18281; S.S.), Polpharma Scientific Foundation, grant No. 4/19/IX/1, the ERA-NET TRANSCAN EJC granted by Fondation ARC (www.fondation-arc.org) (A.P.), and European Union’s Seventh Framework Program (FP7/2007–2013, 282510 (BLUEPRINT)).

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Boer, J. M., Valsecchi, M. G., Hormann, F. M., Antić, Ž., Zaliova, M., Schwab, C., Cazzaniga, G., Arfeuille, C., Cavé, H., Attarbaschi, A., Strehl, S., Escherich, G., Imamura, T., Ohki, K., Grüber, T. A., Sutton, R., Pastorczak, A., Lammens, T., Lambert, F., ... Pieters, R. (2021). Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study. Leukemia, 35(10), 2978-2982. https://doi.org/10.1038/s41375-021-01333-y, https://doi.org/10.1038/s41375-021-01333-y

@article{6f593ae5e30840c5b120ffc09327c080,

title = "Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study",

author = "Boer, \{Judith M.\} and Valsecchi, \{Maria Grazia\} and Hormann, \{Femke M.\} and {\v Z}eljko Anti{\'c} and Marketa Zaliova and Claire Schwab and Giovanni Cazzaniga and Chlo{\'e} Arfeuille and H{\'e}l{\`e}ne Cav{\'e} and Andishe Attarbaschi and Sabine Strehl and Gabriele Escherich and Toshihiko Imamura and Kentaro Ohki and Gr{\"u}ber, \{Tanja A.\} and Rosemary Sutton and Agata Pastorczak and Tim Lammens and Fr{\'e}d{\'e}ric Lambert and Li, \{Chi Kong\} and \{Carrillo de Santa Pau\}, Enrique and Steve Hoffmann and Anja M{\"o}ricke and Harrison, \{Christine J.\} and \{Den Boer\}, \{Monique L.\} and \{De Lorenzo\}, Paola and Stam, \{Ronald W.\} and Bergmann, \{Anke K.\} and Rob Pieters",

note = "Acknowledgements: This study was conducted on behalf of the Ponte di Legno Childhood ALL Working Group. The authors gratefully acknowledge samples and data provided by the Blood Cancer UK Childhood Leukaemia Cell Bank, the Center for Biological Resources (CRB-cancer; BB-0033-00076) of the Robert Debr{\'e} Hospital, the Sydney Children{\textquoteright}s Tumour Bank Network, the Vienna BioCenter Core Facilities (VBCF; www.viennabiocenter.org/ facilities) Next-Generation Sequencing Unit, and the Blueprint Consortium. The authors would like to thank Karin Nebral and Oskar A. Haas for providing genetic data, Georg Mann for clinical data and patient samples, Dagmar Schinnerl for bioinformatics analysis of RNA-sequencing data (Berlin-Frankfurt-M{\"u}nster – Austria study group), Tomasz Szczepanski and Wojciech Mlynarski (Polish Pediatric Leukaemia and Lymphoma Study Group), Martin Schrappe and Martin Zimmermann (Berlin-Frankfurt-M{\"u}nster - Germany/ Switzerland study group), Alex Hoogkamer and Valerie de Haas (Dutch Childhood Oncology Group), Udo zur Stadt (Cooperative Study Group for Childhood ALL), Benoit Brethon (Soci{\'e}t{\'e} Fran{\c c}aise de la lutte contre les Cancers et les leuc{\'e}mies de l{\textquoteright}Enfant et de l{\textquoteright}Adolescent), and Rishi Kotecha (Australian \& New Zealand Childrens Hematology/ Oncology Group). This project was supported by grants from the Oncode Institute (M.L. D.B.), Stichting Kinderoncologisch Centrum Rotterdam (M.L.D.B.), KiKa Foundation (KiKa-264; J.M.B.), vzw Kinderkankerfonds (T.L.), DFG grants (BE6555/1-1 (AKB), BE6555/2-1 (A. K.B., S.H.)), Anniversary Fund of the Oesterreichische Nationalbank (OeNB 18281; S.S.), Polpharma Scientific Foundation, grant No. 4/19/IX/1, the ERA-NET TRANSCAN EJC granted by Fondation ARC (www.fondation-arc.org) (A.P.), and European Union{\textquoteright}s Seventh Framework Program (FP7/2007–2013, 282510 (BLUEPRINT)).",

year = "2021",

month = oct,

doi = "10.1038/s41375-021-01333-y",

language = "English",

volume = "35",

pages = "2978--2982",

journal = "Leukemia",

issn = "0887-6924",

publisher = "Springer Nature",

number = "10",

}

Boer, JM, Valsecchi, MG, Hormann, FM, Antić, Ž, Zaliova, M, Schwab, C, Cazzaniga, G, Arfeuille, C, Cavé, H, Attarbaschi, A, Strehl, S, Escherich, G, Imamura, T, Ohki, K, Grüber, TA, Sutton, R, Pastorczak, A, Lammens, T, Lambert, F, Li, CK, Carrillo de Santa Pau, E, Hoffmann, S, Möricke, A, Harrison, CJ, Den Boer, ML, De Lorenzo, P, Stam, RW, Bergmann, AK & Pieters, R 2021, 'Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study', Leukemia, vol. 35, no. 10, pp. 2978-2982. https://doi.org/10.1038/s41375-021-01333-y, https://doi.org/10.1038/s41375-021-01333-y

TY - JOUR

T1 - Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

AU - Boer, Judith M.

AU - Valsecchi, Maria Grazia

AU - Hormann, Femke M.

AU - Antić, Željko

AU - Zaliova, Marketa

AU - Schwab, Claire

AU - Cazzaniga, Giovanni

AU - Arfeuille, Chloé

AU - Cavé, Hélène

AU - Attarbaschi, Andishe

AU - Strehl, Sabine

AU - Escherich, Gabriele

AU - Imamura, Toshihiko

AU - Ohki, Kentaro

AU - Grüber, Tanja A.

AU - Sutton, Rosemary

AU - Pastorczak, Agata

AU - Lammens, Tim

AU - Lambert, Frédéric

AU - Li, Chi Kong

AU - Carrillo de Santa Pau, Enrique

AU - Hoffmann, Steve

AU - Möricke, Anja

AU - Harrison, Christine J.

AU - Den Boer, Monique L.

AU - De Lorenzo, Paola

AU - Stam, Ronald W.

AU - Bergmann, Anke K.

AU - Pieters, Rob

N1 - Acknowledgements: This study was conducted on behalf of the Ponte di Legno Childhood ALL Working Group. The authors gratefully acknowledge samples and data provided by the Blood Cancer UK Childhood Leukaemia Cell Bank, the Center for Biological Resources (CRB-cancer; BB-0033-00076) of the Robert Debré Hospital, the Sydney Children’s Tumour Bank Network, the Vienna BioCenter Core Facilities (VBCF; www.viennabiocenter.org/ facilities) Next-Generation Sequencing Unit, and the Blueprint Consortium. The authors would like to thank Karin Nebral and Oskar A. Haas for providing genetic data, Georg Mann for clinical data and patient samples, Dagmar Schinnerl for bioinformatics analysis of RNA-sequencing data (Berlin-Frankfurt-Münster – Austria study group), Tomasz Szczepanski and Wojciech Mlynarski (Polish Pediatric Leukaemia and Lymphoma Study Group), Martin Schrappe and Martin Zimmermann (Berlin-Frankfurt-Münster - Germany/ Switzerland study group), Alex Hoogkamer and Valerie de Haas (Dutch Childhood Oncology Group), Udo zur Stadt (Cooperative Study Group for Childhood ALL), Benoit Brethon (Société Française de la lutte contre les Cancers et les leucémies de l’Enfant et de l’Adolescent), and Rishi Kotecha (Australian & New Zealand Childrens Hematology/ Oncology Group). This project was supported by grants from the Oncode Institute (M.L. D.B.), Stichting Kinderoncologisch Centrum Rotterdam (M.L.D.B.), KiKa Foundation (KiKa-264; J.M.B.), vzw Kinderkankerfonds (T.L.), DFG grants (BE6555/1-1 (AKB), BE6555/2-1 (A. K.B., S.H.)), Anniversary Fund of the Oesterreichische Nationalbank (OeNB 18281; S.S.), Polpharma Scientific Foundation, grant No. 4/19/IX/1, the ERA-NET TRANSCAN EJC granted by Fondation ARC (www.fondation-arc.org) (A.P.), and European Union’s Seventh Framework Program (FP7/2007–2013, 282510 (BLUEPRINT)).

PY - 2021/10

Y1 - 2021/10

UR - https://www.scopus.com/pages/publications/85109344285

U2 - 10.1038/s41375-021-01333-y

DO - 10.1038/s41375-021-01333-y

M3 - Comment/Letter to the editor

C2 - 34211097

AN - SCOPUS:85109344285

SN - 0887-6924

VL - 35

SP - 2978

EP - 2982

JO - Leukemia

JF - Leukemia

IS - 10

ER -

Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

Bibliographical note

UN SDGs

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