TY - JOUR
T1 - Fluid therapy in the acute brain injured patient
AU - Ergezen, Saliha
AU - Wiegers, Eveline J.
AU - Klijn, Eva
AU - van der Jagt, Mathieu
N1 - Publisher Copyright: © 2023 EDIZIONI MINERVA MEDICA.
PY - 2023/10
Y1 - 2023/10
N2 - Adequate fluid therapy in the acute brain injured (ABI) patient is essential for maintaining an adequate brain and systemic physiology and preventing intra- and extracranial complications. The target of euvolemia, implying avoidance of both hypovolemia and fluid overloading (or “hypervolemia,” by definition associated with fluid extravasation leading to tissue edema) is of key importance. Primary brain injury can be aggravated by secondary brain injury and systemic deterioration through diverse pathways which can challenge appropriate fluid management, e.g. neuroendocrine and electrolyte disorders, stress cardiomyopathy (also known as cardiac stunning) and neurogenic pulmonary edema. This is an updated expert opinion aiming to provide a practical overview on fluid therapy in the ABI patient, partly based on more recent work and stressing the fact that intravenous fluids should be regarded as drugs, with their inherent potential for both benefit and (unintended) harm.
AB - Adequate fluid therapy in the acute brain injured (ABI) patient is essential for maintaining an adequate brain and systemic physiology and preventing intra- and extracranial complications. The target of euvolemia, implying avoidance of both hypovolemia and fluid overloading (or “hypervolemia,” by definition associated with fluid extravasation leading to tissue edema) is of key importance. Primary brain injury can be aggravated by secondary brain injury and systemic deterioration through diverse pathways which can challenge appropriate fluid management, e.g. neuroendocrine and electrolyte disorders, stress cardiomyopathy (also known as cardiac stunning) and neurogenic pulmonary edema. This is an updated expert opinion aiming to provide a practical overview on fluid therapy in the ABI patient, partly based on more recent work and stressing the fact that intravenous fluids should be regarded as drugs, with their inherent potential for both benefit and (unintended) harm.
UR - http://www.scopus.com/inward/record.url?scp=85175584015&partnerID=8YFLogxK
U2 - 10.23736/S0375-9393.23.17328-7
DO - 10.23736/S0375-9393.23.17328-7
M3 - Review article
C2 - 37822149
AN - SCOPUS:85175584015
SN - 0375-9393
VL - 89
SP - 936
EP - 944
JO - Minerva Anestesiologica
JF - Minerva Anestesiologica
IS - 10
ER -