Gain-of-Function Lipoprotein Lipase Variant rs13702 Modulates Lipid Traits through Disruption of a MicroRNA-410 Seed Site

K Richardson; JA Nettleton; N Rotllan; T Tanaka; CE Smith; CQ Lai; LD Parne; YC Lee; J Lahti; RN Lemaitre; A Manichaikul; M Keller; V Mikkila; J Ngwa; FJA van Rooij; CM Ballentyne; IB Borecki; LA Cupples; M Garcia; Bert Hofman; L Ferrucci; D Mozaffarian; MM Perala; O Raitakari; RP Tracy; DK Arnett; S Bandinelli; E Boerwinkle; JG Eriksson; OH Franco Duran; M Kahonen; M Nalls; DS Siscovick; DK Houston; BM Psaty; J Viikari; JCM Witteman; MO Goodarzi; T Lehtimaki; YM Liu; M.C. Zillikens; YDI Chen; André Uitterlinden; JI Rotter; C Fernandez-Hernando; JM Ordovas

doi:10.1016/j.ajhg.2012.10.020

Gain-of-Function Lipoprotein Lipase Variant rs13702 Modulates Lipid Traits through Disruption of a MicroRNA-410 Seed Site

K Richardson
, JA Nettleton
, N Rotllan
, T Tanaka
, CE Smith
, CQ Lai
, LD Parne
, YC Lee
, J Lahti
, RN Lemaitre
, A Manichaikul
, M Keller
, V Mikkila
, J Ngwa
, FJA van Rooij
, CM Ballentyne
, IB Borecki
, LA Cupples
, M Garcia
, Bert Hofman

L Ferrucci, D Mozaffarian, MM Perala, O Raitakari, RP Tracy, DK Arnett, S Bandinelli, E Boerwinkle, JG Eriksson, OH Franco Duran, M Kahonen, M Nalls, DS Siscovick, DK Houston, BM Psaty, J Viikari, JCM Witteman, MO Goodarzi, T Lehtimaki, YM Liu, M.C. Zillikens, YDI Chen, André Uitterlinden, JI Rotter, C Fernandez-Hernando, JM Ordovas

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

69 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	5-14
Number of pages	10
Journal	American Journal of Human Genetics
Volume	92
Issue number	1
DOIs	https://doi.org/10.1016/j.ajhg.2012.10.020
Publication status	Published - 2013

Research programs

EMC MM-01-39-09-A
EMC NIHES-01-64-02

Access to Document

10.1016/j.ajhg.2012.10.020

http://hdl.handle.net/1765/58031

Cite this

Richardson, K., Nettleton, JA., Rotllan, N., Tanaka, T., Smith, CE., Lai, CQ., Parne, LD., Lee, YC., Lahti, J., Lemaitre, RN., Manichaikul, A., Keller, M., Mikkila, V., Ngwa, J., van Rooij, FJA., Ballentyne, CM., Borecki, IB., Cupples, LA., Garcia, M., ... Ordovas, JM. (2013). Gain-of-Function Lipoprotein Lipase Variant rs13702 Modulates Lipid Traits through Disruption of a MicroRNA-410 Seed Site. American Journal of Human Genetics, 92(1), 5-14. https://doi.org/10.1016/j.ajhg.2012.10.020

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title = "Gain-of-Function Lipoprotein Lipase Variant rs13702 Modulates Lipid Traits through Disruption of a MicroRNA-410 Seed Site",

author = "K Richardson and JA Nettleton and N Rotllan and T Tanaka and CE Smith and CQ Lai and LD Parne and YC Lee and J Lahti and RN Lemaitre and A Manichaikul and M Keller and V Mikkila and J Ngwa and \{van Rooij\}, FJA and CM Ballentyne and IB Borecki and LA Cupples and M Garcia and Bert Hofman and L Ferrucci and D Mozaffarian and MM Perala and O Raitakari and RP Tracy and DK Arnett and S Bandinelli and E Boerwinkle and JG Eriksson and \{Franco Duran\}, OH and M Kahonen and M Nalls and DS Siscovick and DK Houston and BM Psaty and J Viikari and JCM Witteman and MO Goodarzi and T Lehtimaki and YM Liu and M.C. Zillikens and YDI Chen and Andr{\'e} Uitterlinden and JI Rotter and C Fernandez-Hernando and JM Ordovas",

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Richardson, K, Nettleton, JA, Rotllan, N, Tanaka, T, Smith, CE, Lai, CQ, Parne, LD, Lee, YC, Lahti, J, Lemaitre, RN, Manichaikul, A, Keller, M, Mikkila, V, Ngwa, J, van Rooij, FJA, Ballentyne, CM, Borecki, IB, Cupples, LA, Garcia, M, Hofman, B, Ferrucci, L, Mozaffarian, D, Perala, MM, Raitakari, O, Tracy, RP, Arnett, DK, Bandinelli, S, Boerwinkle, E, Eriksson, JG, Franco Duran, OH, Kahonen, M, Nalls, M, Siscovick, DS, Houston, DK, Psaty, BM, Viikari, J, Witteman, JCM, Goodarzi, MO, Lehtimaki, T, Liu, YM, Zillikens, MC, Chen, YDI, Uitterlinden, A, Rotter, JI, Fernandez-Hernando, C & Ordovas, JM 2013, 'Gain-of-Function Lipoprotein Lipase Variant rs13702 Modulates Lipid Traits through Disruption of a MicroRNA-410 Seed Site', American Journal of Human Genetics, vol. 92, no. 1, pp. 5-14. https://doi.org/10.1016/j.ajhg.2012.10.020

TY - JOUR

T1 - Gain-of-Function Lipoprotein Lipase Variant rs13702 Modulates Lipid Traits through Disruption of a MicroRNA-410 Seed Site

AU - Richardson, K

AU - Nettleton, JA

AU - Rotllan, N

AU - Tanaka, T

AU - Smith, CE

AU - Lai, CQ

AU - Parne, LD

AU - Lee, YC

AU - Lahti, J

AU - Lemaitre, RN

AU - Manichaikul, A

AU - Keller, M

AU - Mikkila, V

AU - Ngwa, J

AU - van Rooij, FJA

AU - Ballentyne, CM

AU - Borecki, IB

AU - Cupples, LA

AU - Garcia, M

AU - Hofman, Bert

AU - Ferrucci, L

AU - Mozaffarian, D

AU - Perala, MM

AU - Raitakari, O

AU - Tracy, RP

AU - Arnett, DK

AU - Bandinelli, S

AU - Boerwinkle, E

AU - Eriksson, JG

AU - Franco Duran, OH

AU - Kahonen, M

AU - Nalls, M

AU - Siscovick, DS

AU - Houston, DK

AU - Psaty, BM

AU - Viikari, J

AU - Witteman, JCM

AU - Goodarzi, MO

AU - Lehtimaki, T

AU - Liu, YM

AU - Zillikens, M.C.

AU - Chen, YDI

AU - Uitterlinden, André

AU - Rotter, JI

AU - Fernandez-Hernando, C

AU - Ordovas, JM

PY - 2013

Y1 - 2013

U2 - 10.1016/j.ajhg.2012.10.020

DO - 10.1016/j.ajhg.2012.10.020

M3 - Article

C2 - 23246289

SN - 0002-9297

VL - 92

SP - 5

EP - 14

JO - American Journal of Human Genetics

JF - American Journal of Human Genetics

IS - 1

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