Gallbladder Cancer in the Netherlands: Incidence, Treatment and Survival Patterns since 1989

Carlijn Witjes; Sanne Akker; O (Otto) Visser; Henrike Kos; Esther Vries; J.N.M. IJzermans; Rob de Man; Jan Willem Coebergh; Kees Verhoef

doi:10.1159/000336217

Gallbladder Cancer in the Netherlands: Incidence, Treatment and Survival Patterns since 1989

Carlijn Witjes, Sanne Akker, O (Otto) Visser, Henrike Kos, Esther Vries, J.N.M. IJzermans, Rob de Man, Jan Willem Coebergh, Kees Verhoef

Research output: Contribution to journal › Article › Academic › peer-review

27 Citations (Scopus)

Abstract

Background: To examine recent trends in gallbladder cancer (GBC) in the general population in the Western world, cancer registration data on GBC in the Netherlands were analyzed. Methods: Trends in incidence, treatment and survival, according to gender, age and stage of disease, between 1989 and 2008 for 3,917 patients were studied. Rates were age-standardized to the European standard population (European Standardized Rates - ESR). Results: The incidence rate for GBC in the Netherlands decreased rapidly during the period of 1989-2008, except for males younger than 60 years. Overall survival remained stable, short-term (3-month) and long-term (5-year) relative survival among surgically treated patients increased significantly. Treatment patterns for GBC changed. Surgery decreased from 55% in 1989 to 38% in 2008 (p < 0.001). Chemotherapy and/or irradiation increased from 1.0 to 5.8% (p < 0.001). Receiving best supportive care increased from 44% in 1989 to 57% in 2008 (p < 0.001). Conclusion: The incidence rate for GBC in the Netherlands has decreased rapidly. Treatment patterns for GBC have changed and survival among surgically treated patients has increased. Copyright (c) 2012 S. Karger AG, Basel

Original language	Undefined/Unknown
Pages (from-to)	92-98
Number of pages	7
Journal	Digestive Surgery
Volume	29
Issue number	2
DOIs	https://doi.org/10.1159/000336217
Publication status	Published - 2012

Research programs

EMC MM-03-47-02-A
EMC MM-03-47-11
EMC MM-04-20-02-A
EMC MM-04-47-07
EMC NIHES-02-65-02

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1159/000336217

http://hdl.handle.net/1765/63344

Cite this

@article{84aa55cd61a24752800a662a7cba2c7b,

title = "Gallbladder Cancer in the Netherlands: Incidence, Treatment and Survival Patterns since 1989",

abstract = "Background: To examine recent trends in gallbladder cancer (GBC) in the general population in the Western world, cancer registration data on GBC in the Netherlands were analyzed. Methods: Trends in incidence, treatment and survival, according to gender, age and stage of disease, between 1989 and 2008 for 3,917 patients were studied. Rates were age-standardized to the European standard population (European Standardized Rates - ESR). Results: The incidence rate for GBC in the Netherlands decreased rapidly during the period of 1989-2008, except for males younger than 60 years. Overall survival remained stable, short-term (3-month) and long-term (5-year) relative survival among surgically treated patients increased significantly. Treatment patterns for GBC changed. Surgery decreased from 55% in 1989 to 38% in 2008 (p < 0.001). Chemotherapy and/or irradiation increased from 1.0 to 5.8% (p < 0.001). Receiving best supportive care increased from 44% in 1989 to 57% in 2008 (p < 0.001). Conclusion: The incidence rate for GBC in the Netherlands has decreased rapidly. Treatment patterns for GBC have changed and survival among surgically treated patients has increased. Copyright (c) 2012 S. Karger AG, Basel",

author = "Carlijn Witjes and Sanne Akker and Visser, {O (Otto)} and Henrike Kos and Esther Vries and J.N.M. IJzermans and {de Man}, Rob and Coebergh, {Jan Willem} and Kees Verhoef",

year = "2012",

doi = "10.1159/000336217",

language = "Undefined/Unknown",

volume = "29",

pages = "92--98",

journal = "Digestive Surgery",

issn = "0253-4886",

publisher = "Karger",

number = "2",

}

TY - JOUR

T1 - Gallbladder Cancer in the Netherlands: Incidence, Treatment and Survival Patterns since 1989

AU - Witjes, Carlijn

AU - Akker, Sanne

AU - Visser, O (Otto)

AU - Kos, Henrike

AU - Vries, Esther

AU - IJzermans, J.N.M.

AU - de Man, Rob

AU - Coebergh, Jan Willem

AU - Verhoef, Kees

PY - 2012

Y1 - 2012

N2 - Background: To examine recent trends in gallbladder cancer (GBC) in the general population in the Western world, cancer registration data on GBC in the Netherlands were analyzed. Methods: Trends in incidence, treatment and survival, according to gender, age and stage of disease, between 1989 and 2008 for 3,917 patients were studied. Rates were age-standardized to the European standard population (European Standardized Rates - ESR). Results: The incidence rate for GBC in the Netherlands decreased rapidly during the period of 1989-2008, except for males younger than 60 years. Overall survival remained stable, short-term (3-month) and long-term (5-year) relative survival among surgically treated patients increased significantly. Treatment patterns for GBC changed. Surgery decreased from 55% in 1989 to 38% in 2008 (p < 0.001). Chemotherapy and/or irradiation increased from 1.0 to 5.8% (p < 0.001). Receiving best supportive care increased from 44% in 1989 to 57% in 2008 (p < 0.001). Conclusion: The incidence rate for GBC in the Netherlands has decreased rapidly. Treatment patterns for GBC have changed and survival among surgically treated patients has increased. Copyright (c) 2012 S. Karger AG, Basel

AB - Background: To examine recent trends in gallbladder cancer (GBC) in the general population in the Western world, cancer registration data on GBC in the Netherlands were analyzed. Methods: Trends in incidence, treatment and survival, according to gender, age and stage of disease, between 1989 and 2008 for 3,917 patients were studied. Rates were age-standardized to the European standard population (European Standardized Rates - ESR). Results: The incidence rate for GBC in the Netherlands decreased rapidly during the period of 1989-2008, except for males younger than 60 years. Overall survival remained stable, short-term (3-month) and long-term (5-year) relative survival among surgically treated patients increased significantly. Treatment patterns for GBC changed. Surgery decreased from 55% in 1989 to 38% in 2008 (p < 0.001). Chemotherapy and/or irradiation increased from 1.0 to 5.8% (p < 0.001). Receiving best supportive care increased from 44% in 1989 to 57% in 2008 (p < 0.001). Conclusion: The incidence rate for GBC in the Netherlands has decreased rapidly. Treatment patterns for GBC have changed and survival among surgically treated patients has increased. Copyright (c) 2012 S. Karger AG, Basel

U2 - 10.1159/000336217

DO - 10.1159/000336217

M3 - Article

C2 - 22441693

SN - 0253-4886

VL - 29

SP - 92

EP - 98

JO - Digestive Surgery

JF - Digestive Surgery

IS - 2

ER -