Genes predict village of origin in rural Europe

C O'Dushlaine; R McQuillan; ME Weale; DJM Crouch; A Johansson; Yuriy Aulchenko; CS Franklin; O Polasek; C Fuchsberger; A Corvin; AA Hicks; V Vitart; C Hayward; SH Wild; T Meitinger; Cornelia Duijn; U Gyllensten; AF Wright; H Campbell; PP Pramstaller; I Rudan; JF Wilson

doi:10.1038/ejhg.2010.92

Genes predict village of origin in rural Europe

C O'Dushlaine, R McQuillan, ME Weale, DJM Crouch, A Johansson, Yuriy Aulchenko, CS Franklin, O Polasek, C Fuchsberger, A Corvin, AA Hicks, V Vitart, C Hayward, SH Wild, T Meitinger, Cornelia Duijn, U Gyllensten, AF Wright, H Campbell, PP PramstallerI Rudan, JF Wilson

Epidemiology

Research output: Contribution to journal › Article › Academic › peer-review

21 Citations (Scopus)

Abstract

The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals. European Journal of Human Genetics (2010) 18, 1269-1270; doi: 10.1038/ejhg.2010.92; published online 23 June 2010

Original language	Undefined/Unknown
Pages (from-to)	1269-1270
Number of pages	2
Journal	European Journal of Human Genetics
Volume	18
Issue number	11
DOIs	https://doi.org/10.1038/ejhg.2010.92
Publication status	Published - 2010

Research programs

EMC NIHES-01-64-02

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/ejhg.2010.92

http://hdl.handle.net/1765/28257

Cite this

O'Dushlaine, C., McQuillan, R., Weale, ME., Crouch, DJM., Johansson, A., Aulchenko, Y., Franklin, CS., Polasek, O., Fuchsberger, C., Corvin, A., Hicks, AA., Vitart, V., Hayward, C., Wild, SH., Meitinger, T., Duijn, C., Gyllensten, U., Wright, AF., Campbell, H., ... Wilson, JF. (2010). Genes predict village of origin in rural Europe. European Journal of Human Genetics, 18(11), 1269-1270. https://doi.org/10.1038/ejhg.2010.92

@article{4ab27f8c381847aba06a6d5eeeae955c,

title = "Genes predict village of origin in rural Europe",

abstract = "The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals. European Journal of Human Genetics (2010) 18, 1269-1270; doi: 10.1038/ejhg.2010.92; published online 23 June 2010",

author = "C O'Dushlaine and R McQuillan and ME Weale and DJM Crouch and A Johansson and Yuriy Aulchenko and CS Franklin and O Polasek and C Fuchsberger and A Corvin and AA Hicks and V Vitart and C Hayward and SH Wild and T Meitinger and Cornelia Duijn and U Gyllensten and AF Wright and H Campbell and PP Pramstaller and I Rudan and JF Wilson",

year = "2010",

doi = "10.1038/ejhg.2010.92",

language = "Undefined/Unknown",

volume = "18",

pages = "1269--1270",

journal = "European Journal of Human Genetics",

issn = "1018-4813",

publisher = "Springer Nature",

number = "11",

}

O'Dushlaine, C, McQuillan, R, Weale, ME, Crouch, DJM, Johansson, A, Aulchenko, Y, Franklin, CS, Polasek, O, Fuchsberger, C, Corvin, A, Hicks, AA, Vitart, V, Hayward, C, Wild, SH, Meitinger, T, Duijn, C, Gyllensten, U, Wright, AF, Campbell, H, Pramstaller, PP, Rudan, I & Wilson, JF 2010, 'Genes predict village of origin in rural Europe', European Journal of Human Genetics, vol. 18, no. 11, pp. 1269-1270. https://doi.org/10.1038/ejhg.2010.92

TY - JOUR

T1 - Genes predict village of origin in rural Europe

AU - O'Dushlaine, C

AU - McQuillan, R

AU - Weale, ME

AU - Crouch, DJM

AU - Johansson, A

AU - Aulchenko, Yuriy

AU - Franklin, CS

AU - Polasek, O

AU - Fuchsberger, C

AU - Corvin, A

AU - Hicks, AA

AU - Vitart, V

AU - Hayward, C

AU - Wild, SH

AU - Meitinger, T

AU - Duijn, Cornelia

AU - Gyllensten, U

AU - Wright, AF

AU - Campbell, H

AU - Pramstaller, PP

AU - Rudan, I

AU - Wilson, JF

PY - 2010

Y1 - 2010

N2 - The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals. European Journal of Human Genetics (2010) 18, 1269-1270; doi: 10.1038/ejhg.2010.92; published online 23 June 2010

AB - The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals. European Journal of Human Genetics (2010) 18, 1269-1270; doi: 10.1038/ejhg.2010.92; published online 23 June 2010

U2 - 10.1038/ejhg.2010.92

DO - 10.1038/ejhg.2010.92

M3 - Article

C2 - 20571506

SN - 1018-4813

VL - 18

SP - 1269

EP - 1270

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

IS - 11

ER -