Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

Pooja Mandaviya; R Joehanes; D Aissi; B Kuhnel; RE Marioni; V Truong; Lisette Stolk; M Beekman; MJ Bonder; L Franke; C Gieger; TX Huan; Arfan Ikram; S Kunze; LM Liang; J Lindemann; CY Liu; AF Mcrae; MM Mendelson; M Muller-Nurasyid; A Peters; PE (Eline) Slagboom; JM Starr; DA Tregouet; André Uitterlinden; MMJ van Greevenbroek; D van Heemst; M van Iterson; PS Wells; C Yao; IJ Deary; F Gagnon; BT Heijmans; D Levy; PE Morange; M Waldenberger; Sandra Heil; Joyce van Meurs

doi:10.1371/journal.pone.0182472

Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

Pooja Mandaviya, R Joehanes, D Aissi, B Kuhnel, RE Marioni, V Truong, Lisette Stolk, M Beekman, MJ Bonder, L Franke, C Gieger, TX Huan, Arfan Ikram, S Kunze, LM Liang, J Lindemann, CY Liu, AF Mcrae, MM Mendelson, M Muller-NurasyidA Peters, PE (Eline) Slagboom, JM Starr, DA Tregouet, André Uitterlinden, MMJ van Greevenbroek, D van Heemst, M van Iterson, PS Wells, C Yao, IJ Deary, F Gagnon, BT Heijmans, D Levy, PE Morange, M Waldenberger, Sandra Heil, Joyce van Meurs

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Original language	Undefined/Unknown
Article number	e0182472
Journal	PLoS One (online)
Volume	12
Issue number	10
DOIs	https://doi.org/10.1371/journal.pone.0182472
Publication status	Published - 2017

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Cite this

Mandaviya, P., Joehanes, R., Aissi, D., Kuhnel, B., Marioni, RE., Truong, V., Stolk, L., Beekman, M., Bonder, MJ., Franke, L., Gieger, C., Huan, TX., Ikram, A., Kunze, S., Liang, LM., Lindemann, J., Liu, CY., Mcrae, AF., Mendelson, MM., ... van Meurs, J. (2017). Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes. PLoS One (online), 12(10), [e0182472]. https://doi.org/10.1371/journal.pone.0182472

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title = "Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes",

author = "Pooja Mandaviya and R Joehanes and D Aissi and B Kuhnel and RE Marioni and V Truong and Lisette Stolk and M Beekman and MJ Bonder and L Franke and C Gieger and TX Huan and Arfan Ikram and S Kunze and LM Liang and J Lindemann and CY Liu and AF Mcrae and MM Mendelson and M Muller-Nurasyid and A Peters and Slagboom, {PE (Eline)} and JM Starr and DA Tregouet and Andr{\'e} Uitterlinden and {van Greevenbroek}, MMJ and {van Heemst}, D and {van Iterson}, M and PS Wells and C Yao and IJ Deary and F Gagnon and BT Heijmans and D Levy and PE Morange and M Waldenberger and Sandra Heil and {van Meurs}, Joyce",

year = "2017",

doi = "10.1371/journal.pone.0182472",

language = "Undefined/Unknown",

volume = "12",

journal = "PLoS ONE",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "10",

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Mandaviya, P, Joehanes, R, Aissi, D, Kuhnel, B, Marioni, RE, Truong, V, Stolk, L, Beekman, M, Bonder, MJ, Franke, L, Gieger, C, Huan, TX, Ikram, A, Kunze, S, Liang, LM, Lindemann, J, Liu, CY, Mcrae, AF, Mendelson, MM, Muller-Nurasyid, M, Peters, A, Slagboom, PE, Starr, JM, Tregouet, DA, Uitterlinden, A, van Greevenbroek, MMJ, van Heemst, D, van Iterson, M, Wells, PS, Yao, C, Deary, IJ, Gagnon, F, Heijmans, BT, Levy, D, Morange, PE, Waldenberger, M, Heil, S & van Meurs, J 2017, 'Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes', PLoS One (online), vol. 12, no. 10, e0182472. https://doi.org/10.1371/journal.pone.0182472

TY - JOUR

T1 - Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

AU - Mandaviya, Pooja

AU - Joehanes, R

AU - Aissi, D

AU - Kuhnel, B

AU - Marioni, RE

AU - Truong, V

AU - Stolk, Lisette

AU - Beekman, M

AU - Bonder, MJ

AU - Franke, L

AU - Gieger, C

AU - Huan, TX

AU - Ikram, Arfan

AU - Kunze, S

AU - Liang, LM

AU - Lindemann, J

AU - Liu, CY

AU - Mcrae, AF

AU - Mendelson, MM

AU - Muller-Nurasyid, M

AU - Peters, A

AU - Slagboom, PE (Eline)

AU - Starr, JM

AU - Tregouet, DA

AU - Uitterlinden, André

AU - van Greevenbroek, MMJ

AU - van Heemst, D

AU - van Iterson, M

AU - Wells, PS

AU - Yao, C

AU - Deary, IJ

AU - Gagnon, F

AU - Heijmans, BT

AU - Levy, D

AU - Morange, PE

AU - Waldenberger, M

AU - Heil, Sandra

AU - van Meurs, Joyce

PY - 2017

Y1 - 2017

U2 - 10.1371/journal.pone.0182472

DO - 10.1371/journal.pone.0182472

M3 - Article

VL - 12

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 10

M1 - e0182472

ER -