Genetics of osteoporosis

Fernando Rivadeneira; André G. Uitterlinden

doi:10.1016/B978-0-12-813073-5.00018-6

Genetics of osteoporosis

Fernando Rivadeneira, André G. Uitterlinden

Internal Medicine

Research output: Chapter/Conference proceeding › Chapter › Academic

2 Citations (Scopus)

Abstract

The major diseases of the locomotor system, that is, osteoarthritis and osteoporosis, are so-called complex diseases. These include the typical common age-related disorders such as cancer, cardiovascular disease, and diabetes and share that they are caused by hundreds of genetic factors and are characterized by interplay of genes and environment. Epidemiological research of these complex diseases has identified anthropometric, behavioral, and serum parameters as risk factors for incidence and progression of the disease. However, genetic (DNA) polymorphisms have gained considerable interest in this respect, fueled by increasingly large genome-wide association studies (GWASs).

Original language	English
Title of host publication	Marcus and Feldman’s Osteoporosis
Publisher	Elsevier
Chapter	18
Pages	405-451
Number of pages	47
ISBN (Electronic)	9780128130735
DOIs	https://doi.org/10.1016/B978-0-12-813073-5.00018-6
Publication status	Published - 2021

Bibliographical note

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/B978-0-12-813073-5.00018-6

Cite this

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Genetics of osteoporosis

Abstract

Bibliographical note

UN SDGs

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