Abstract
We conducted a genome-wide association study of male breast cancer comprising 823 cases and 2,795 controls of European ancestry, with validation in independent sample sets totaling 438 cases and 474 controls. A SNP in RAD51B at 14q24.1 was significantly associated with male breast cancer risk (P = 3.02 x 10(-13); odds ratio (OR) = 1.57). We also refine association at 16q12.1 to a SNP within TOX3 (P = 3.87 x 10(-15); OR = 1.50).
Original language | Undefined/Unknown |
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Pages (from-to) | 1182-1184 |
Number of pages | 3 |
Journal | Nature Genetics |
Volume | 44 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2012 |
Research programs
- EMC MGC-02-96-01