Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

X Jiang; PF O'Reilly; H Aschard; YH Hsu; JB Richards; J Dupuis; E Ingelsson; D Karasik; S Pilz; D Berry; B Kestenbaum; JS Zheng; JN Luan; E Sofianopoulou; EA Streeten; D Albanes; PL Lutsey; L Yao; WH Tang; MJ Econs; H Wallaschofski; H Volzke; A Zhou; C Power; MI McCarthy; ED Michos; E Boerwinkle; SJ Weinstein; N D Freedman; WY Huang; NM Schoor; Nathalie van der Velde; LCPGM (Lisette) de Groot; Anke Enneman; LA Cupples; SL Booth; RS Vasan; CT Liu; YH Zhou; S Ripatti; C Ohlsson; L Vandenput; M Lorentzon; JG Eriksson; MK Shea; DK Houston; SB Kritchevsky; YM Liu; KK Lohman; L Ferrucci; M Peacock; C Gieger; M Beekman; E Slagboom; J Deelen; D van Heemst; ME Kleber; W Marz; IH (Ian) Boer; AC Wood; JI Rotter; SS Rich; C Robinson-Cohen; Mariska Heijer; MR Jarvelin; A Cavadino; PK Joshi; JF Wilson; C Hayward; L Lind; K Michaelsson; S Trompet; M.C. Zillikens; André Uitterlinden; Fernando Rivadeneira; Linda Broer; L Zgaga; H Campbell; E Theodoratou; SM Farrington; M Timofeeva; MG Dunlop; AM Valdes; E Tikkanen; T Lehtimaki; LP Lyytikainen; M Kahonen; OT Raitakari; V Mikkila; Arfan Ikram; N Sattar; JW Jukema; NJ Wareham; C Langenberg; NG Forouhi; TE Gundersen; KT Khaw; AS Butterworth; J Danesh; T Spector; TJ Wang; E Hypponen; P Kraft; DP Kiel

doi:10.1038/s41467-017-02662-2

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

X Jiang
, PF O'Reilly
, H Aschard
, YH Hsu
, JB Richards
, J Dupuis
, E Ingelsson
, D Karasik
, S Pilz
, D Berry
, B Kestenbaum
, JS Zheng
, JN Luan
, E Sofianopoulou
, EA Streeten
, D Albanes
, PL Lutsey
, L Yao
, WH Tang
, MJ Econs

H Wallaschofski, H Volzke, A Zhou, C Power, MI McCarthy, ED Michos, E Boerwinkle, SJ Weinstein, N D Freedman, WY Huang, NM Schoor, Nathalie van der Velde, LCPGM (Lisette) de Groot, Anke Enneman, LA Cupples, SL Booth, RS Vasan, CT Liu, YH Zhou, S Ripatti, C Ohlsson, L Vandenput, M Lorentzon, JG Eriksson, MK Shea, DK Houston, SB Kritchevsky, YM Liu, KK Lohman, L Ferrucci, M Peacock, C Gieger, M Beekman, E Slagboom, J Deelen, D van Heemst, ME Kleber, W Marz, IH (Ian) Boer, AC Wood, JI Rotter, SS Rich, C Robinson-Cohen, Mariska Heijer, MR Jarvelin, A Cavadino, PK Joshi, JF Wilson, C Hayward, L Lind, K Michaelsson, S Trompet, M.C. Zillikens, André Uitterlinden, Fernando Rivadeneira, Linda Broer, L Zgaga, H Campbell, E Theodoratou, SM Farrington, M Timofeeva, MG Dunlop, AM Valdes, E Tikkanen, T Lehtimaki, LP Lyytikainen, M Kahonen, OT Raitakari, V Mikkila, Arfan Ikram, N Sattar, JW Jukema, NJ Wareham, C Langenberg, NG Forouhi, TE Gundersen, KT Khaw, AS Butterworth, J Danesh, T Spector, TJ Wang, E Hypponen, P Kraft, DP Kiel

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Research output: Contribution to journal › Article › Academic › peer-review

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53 Downloads (Pure)

Original language	English
Article number	260
Journal	Nature Communications
Volume	9
DOIs	https://doi.org/10.1038/s41467-017-02662-2
Publication status	Published - 2018

Research programs

EMC MM-01-39-02
EMC MM-01-39-09-A
EMC OR-01-39-08

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10.1038/s41467-017-02662-2

REPUB_104479-OA.pdfFinal published version, 1.13 MB

http://hdl.handle.net/1765/104479

Cite this

Jiang, X., O'Reilly, PF., Aschard, H., Hsu, YH., Richards, JB., Dupuis, J., Ingelsson, E., Karasik, D., Pilz, S., Berry, D., Kestenbaum, B., Zheng, JS., Luan, JN., Sofianopoulou, E., Streeten, EA., Albanes, D., Lutsey, PL., Yao, L., Tang, WH., ... Kiel, DP. (2018). Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Nature Communications, 9, Article 260. https://doi.org/10.1038/s41467-017-02662-2

@article{ddcedc41e8fc490ca4d73a8b08e080d9,

title = "Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels",

author = "X Jiang and PF O'Reilly and H Aschard and YH Hsu and JB Richards and J Dupuis and E Ingelsson and D Karasik and S Pilz and D Berry and B Kestenbaum and JS Zheng and JN Luan and E Sofianopoulou and EA Streeten and D Albanes and PL Lutsey and L Yao and WH Tang and MJ Econs and H Wallaschofski and H Volzke and A Zhou and C Power and MI McCarthy and ED Michos and E Boerwinkle and SJ Weinstein and Freedman, \{N D\} and WY Huang and NM Schoor and \{van der Velde\}, Nathalie and \{de Groot\}, \{LCPGM (Lisette)\} and Anke Enneman and LA Cupples and SL Booth and RS Vasan and CT Liu and YH Zhou and S Ripatti and C Ohlsson and L Vandenput and M Lorentzon and JG Eriksson and MK Shea and DK Houston and SB Kritchevsky and YM Liu and KK Lohman and L Ferrucci and M Peacock and C Gieger and M Beekman and E Slagboom and J Deelen and \{van Heemst\}, D and ME Kleber and W Marz and Boer, \{IH (Ian)\} and AC Wood and JI Rotter and SS Rich and C Robinson-Cohen and Mariska Heijer and MR Jarvelin and A Cavadino and PK Joshi and JF Wilson and C Hayward and L Lind and K Michaelsson and S Trompet and M.C. Zillikens and Andr{\'e} Uitterlinden and Fernando Rivadeneira and Linda Broer and L Zgaga and H Campbell and E Theodoratou and SM Farrington and M Timofeeva and MG Dunlop and AM Valdes and E Tikkanen and T Lehtimaki and LP Lyytikainen and M Kahonen and OT Raitakari and V Mikkila and Arfan Ikram and N Sattar and JW Jukema and NJ Wareham and C Langenberg and NG Forouhi and TE Gundersen and KT Khaw and AS Butterworth and J Danesh and T Spector and TJ Wang and E Hypponen and P Kraft and DP Kiel",

year = "2018",

doi = "10.1038/s41467-017-02662-2",

language = "English",

volume = "9",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Research",

}

Jiang, X, O'Reilly, PF, Aschard, H, Hsu, YH, Richards, JB, Dupuis, J, Ingelsson, E, Karasik, D, Pilz, S, Berry, D, Kestenbaum, B, Zheng, JS, Luan, JN, Sofianopoulou, E, Streeten, EA, Albanes, D, Lutsey, PL, Yao, L, Tang, WH, Econs, MJ, Wallaschofski, H, Volzke, H, Zhou, A, Power, C, McCarthy, MI, Michos, ED, Boerwinkle, E, Weinstein, SJ, Freedman, ND, Huang, WY, Schoor, NM, van der Velde, N, de Groot, LCPGM, Enneman, A, Cupples, LA, Booth, SL, Vasan, RS, Liu, CT, Zhou, YH, Ripatti, S, Ohlsson, C, Vandenput, L, Lorentzon, M, Eriksson, JG, Shea, MK, Houston, DK, Kritchevsky, SB, Liu, YM, Lohman, KK, Ferrucci, L, Peacock, M, Gieger, C, Beekman, M, Slagboom, E, Deelen, J, van Heemst, D, Kleber, ME, Marz, W, Boer, IH, Wood, AC, Rotter, JI, Rich, SS, Robinson-Cohen, C, Heijer, M, Jarvelin, MR, Cavadino, A, Joshi, PK, Wilson, JF, Hayward, C, Lind, L, Michaelsson, K, Trompet, S, Zillikens, MC, Uitterlinden, A, Rivadeneira, F , Broer, L, Zgaga, L, Campbell, H, Theodoratou, E, Farrington, SM, Timofeeva, M, Dunlop, MG, Valdes, AM, Tikkanen, E, Lehtimaki, T, Lyytikainen, LP, Kahonen, M, Raitakari, OT, Mikkila, V, Ikram, A, Sattar, N, Jukema, JW, Wareham, NJ, Langenberg, C, Forouhi, NG, Gundersen, TE, Khaw, KT, Butterworth, AS, Danesh, J, Spector, T, Wang, TJ, Hypponen, E, Kraft, P & Kiel, DP 2018, 'Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels', Nature Communications, vol. 9, 260. https://doi.org/10.1038/s41467-017-02662-2

TY - JOUR

T1 - Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

AU - Jiang, X

AU - O'Reilly, PF

AU - Aschard, H

AU - Hsu, YH

AU - Richards, JB

AU - Dupuis, J

AU - Ingelsson, E

AU - Karasik, D

AU - Pilz, S

AU - Berry, D

AU - Kestenbaum, B

AU - Zheng, JS

AU - Luan, JN

AU - Sofianopoulou, E

AU - Streeten, EA

AU - Albanes, D

AU - Lutsey, PL

AU - Yao, L

AU - Tang, WH

AU - Econs, MJ

AU - Wallaschofski, H

AU - Volzke, H

AU - Zhou, A

AU - Power, C

AU - McCarthy, MI

AU - Michos, ED

AU - Boerwinkle, E

AU - Weinstein, SJ

AU - Freedman, N D

AU - Huang, WY

AU - Schoor, NM

AU - van der Velde, Nathalie

AU - de Groot, LCPGM (Lisette)

AU - Enneman, Anke

AU - Cupples, LA

AU - Booth, SL

AU - Vasan, RS

AU - Liu, CT

AU - Zhou, YH

AU - Ripatti, S

AU - Ohlsson, C

AU - Vandenput, L

AU - Lorentzon, M

AU - Eriksson, JG

AU - Shea, MK

AU - Houston, DK

AU - Kritchevsky, SB

AU - Liu, YM

AU - Lohman, KK

AU - Ferrucci, L

AU - Peacock, M

AU - Gieger, C

AU - Beekman, M

AU - Slagboom, E

AU - Deelen, J

AU - van Heemst, D

AU - Kleber, ME

AU - Marz, W

AU - Boer, IH (Ian)

AU - Wood, AC

AU - Rotter, JI

AU - Rich, SS

AU - Robinson-Cohen, C

AU - Heijer, Mariska

AU - Jarvelin, MR

AU - Cavadino, A

AU - Joshi, PK

AU - Wilson, JF

AU - Hayward, C

AU - Lind, L

AU - Michaelsson, K

AU - Trompet, S

AU - Zillikens, M.C.

AU - Uitterlinden, André

AU - Rivadeneira, Fernando

AU - Broer, Linda

AU - Zgaga, L

AU - Campbell, H

AU - Theodoratou, E

AU - Farrington, SM

AU - Timofeeva, M

AU - Dunlop, MG

AU - Valdes, AM

AU - Tikkanen, E

AU - Lehtimaki, T

AU - Lyytikainen, LP

AU - Kahonen, M

AU - Raitakari, OT

AU - Mikkila, V

AU - Ikram, Arfan

AU - Sattar, N

AU - Jukema, JW

AU - Wareham, NJ

AU - Langenberg, C

AU - Forouhi, NG

AU - Gundersen, TE

AU - Khaw, KT

AU - Butterworth, AS

AU - Danesh, J

AU - Spector, T

AU - Wang, TJ

AU - Hypponen, E

AU - Kraft, P

AU - Kiel, DP

PY - 2018

Y1 - 2018

U2 - 10.1038/s41467-017-02662-2

DO - 10.1038/s41467-017-02662-2

M3 - Article

C2 - 29343764

SN - 2041-1723

VL - 9

JO - Nature Communications

JF - Nature Communications

M1 - 260

ER -