Genome-wide associations for birth weight and correlations with adult disease

M Horikoshi; RN Beaumont; FR Day; NM Warrington; Marjolein Kooijman; J Fernandez-Tajes; B Feenstra; NR van Zuydam; KJ Gaulton; N Grarup; JP Bradfield; DP Strachan; R Li-Gao; TS Ahluwalia; E Kreiner; R Rueedi; LP Lyytikainen; DL Cousminer; Fenny Wu; E Thiering; CA Wang; CT Have; JJ (Jouke Jan) Hottenga; N Vilor-Tejedor; PK Joshi; ETH Boh; I Ntalla; N Pitkanen; A Mahajan; Elisa Leeuwen; R Joro; V Lagou; M Nodzenski; LA Diver; KT Zondervan; M Bustamante; P Marques-Vidal; JM Mercader; AJ Bennett; N Rahmioglu; DR Nyholt; RCW Ma; CHT Tam; WH Tam; SK Ganesh; FJA van Rooij; SE Jones; PR Loh; KS Ruth; MA Tuke; J Tyrrell; AR Wood; H Yaghootkar; DM Scholtens; L Paternoster; I Prokopenko; P Kovacs; M Atalay; SM Willems; K Panoutsopoulou; X Wang; L Carstensen; F Geller; KE Schraut; M Murcia; CEM (Toos) van Beijsterveldt; G Willemsen; EVR Appel; CE Fonvig; C Trier; CMT Tiesler; M Standl; Z Kutalik; S Bonas-Guarch; DM Hougaard; F Sanchez; D Torrents; J Waage; MV Hollegaard; HG de Haan; FR Rosendaal; C Medina-Gomez; SM Ring; G Hemani; G McMahon; NR Robertson; CJ Groves; C Langenberg; J Luan; RA Scott; JH Zhao; FD Mentch; SM MacKenzie; RM Reynolds; WL Lowe; A Tonjes; M Stumvoll; V Lindi; TA Lakka; Cornelia Duijn; W Kiess; A Korner; TIA Sorensen; H Niinikoski; K Pahkala; OT Raitakari; E Zeggini; GV Dedoussis; YY Teo; SM Saw; M Melbye; H Campbell; JF Wilson; M Vrijheid; EJCN de Geus; DI Boomsma; HN Kadarmideen; JC Holm; T Hansen; S Sebert; AT Hattersley; LJ Beilin; JP Newnham; CE Pennell; J (Joachim) Heinrich; LS Adair; JB Borja; KL Mohlke; JG Eriksson; E Widen; M Kahonen; JS Viikari; T Lehtimaki; P Vollenweider; K Bonnelykke; H Bisgaard; Dennis Mook; Bert Hofman; Fernando Rivadeneira; André Uitterlinden; C Pisinger; O Pedersen; C Power; E Hypponen; NJ Wareham; H Hakonarson; E Davies; BR Walker; Vincent Jaddoe; MR Jarvelin; SFA Grant; AA Vaag; DA Lawlor; TM Frayling; GD Smith; AP Morris; KK Ong; Janine Felix; NJ Timpson; JRB Perry; DM Evans; MI McCarthy; RM Freathy

doi:10.1038/nature19806

Genome-wide associations for birth weight and correlations with adult disease

M Horikoshi
, RN Beaumont
, FR Day
, NM Warrington
, Marjolein Kooijman
, J Fernandez-Tajes
, B Feenstra
, NR van Zuydam
, KJ Gaulton
, N Grarup
, JP Bradfield
, DP Strachan
, R Li-Gao
, TS Ahluwalia
, E Kreiner
, R Rueedi
, LP Lyytikainen
, DL Cousminer
, Fenny Wu
, E Thiering

CA Wang, CT Have, JJ (Jouke Jan) Hottenga, N Vilor-Tejedor, PK Joshi, ETH Boh, I Ntalla, N Pitkanen, A Mahajan, Elisa Leeuwen, R Joro, V Lagou, M Nodzenski, LA Diver, KT Zondervan, M Bustamante, P Marques-Vidal, JM Mercader, AJ Bennett, N Rahmioglu, DR Nyholt, RCW Ma, CHT Tam, WH Tam, SK Ganesh, FJA van Rooij, SE Jones, PR Loh, KS Ruth, MA Tuke, J Tyrrell, AR Wood, H Yaghootkar, DM Scholtens, L Paternoster, I Prokopenko, P Kovacs, M Atalay, SM Willems, K Panoutsopoulou, X Wang, L Carstensen, F Geller, KE Schraut, M Murcia, CEM (Toos) van Beijsterveldt, G Willemsen, EVR Appel, CE Fonvig, C Trier, CMT Tiesler, M Standl, Z Kutalik, S Bonas-Guarch, DM Hougaard, F Sanchez, D Torrents, J Waage, MV Hollegaard, HG de Haan, FR Rosendaal, C Medina-Gomez, SM Ring, G Hemani, G McMahon, NR Robertson, CJ Groves, C Langenberg, J Luan, RA Scott, JH Zhao, FD Mentch, SM MacKenzie, RM Reynolds, WL Lowe, A Tonjes, M Stumvoll, V Lindi, TA Lakka, Cornelia Duijn, W Kiess, A Korner, TIA Sorensen, H Niinikoski, K Pahkala, OT Raitakari, E Zeggini, GV Dedoussis, YY Teo, SM Saw, M Melbye, H Campbell, JF Wilson, M Vrijheid, EJCN de Geus, DI Boomsma, HN Kadarmideen, JC Holm, T Hansen, S Sebert, AT Hattersley, LJ Beilin, JP Newnham, CE Pennell, J (Joachim) Heinrich, LS Adair, JB Borja, KL Mohlke, JG Eriksson, E Widen, M Kahonen, JS Viikari, T Lehtimaki, P Vollenweider, K Bonnelykke, H Bisgaard, Dennis Mook, Bert Hofman, Fernando Rivadeneira, André Uitterlinden, C Pisinger, O Pedersen, C Power, E Hypponen, NJ Wareham, H Hakonarson, E Davies, BR Walker, Vincent Jaddoe, MR Jarvelin, SFA Grant, AA Vaag, DA Lawlor, TM Frayling, GD Smith, AP Morris, KK Ong, Janine Felix, NJ Timpson, JRB Perry, DM Evans, MI McCarthy, RM Freathy

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

395 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	248-252
Number of pages	5
Journal	Nature
Volume	538
Issue number	7624
DOIs	https://doi.org/10.1038/nature19806
Publication status	Published - 2016

Research programs

EMC MM-04-54-08-A
EMC NIHES-01-64-01

Access to Document

10.1038/nature19806

http://hdl.handle.net/1765/96451

Cite this

Horikoshi, M., Beaumont, RN., Day, FR., Warrington, NM., Kooijman, M., Fernandez-Tajes, J., Feenstra, B., van Zuydam, NR., Gaulton, KJ., Grarup, N., Bradfield, JP., Strachan, DP., Li-Gao, R., Ahluwalia, TS., Kreiner, E., Rueedi, R., Lyytikainen, LP., Cousminer, DL., Wu, F., ... Freathy, RM. (2016). Genome-wide associations for birth weight and correlations with adult disease. Nature, 538(7624), 248-252. https://doi.org/10.1038/nature19806

@article{e992f11bb9a44c60bca2c6ab1950d652,

title = "Genome-wide associations for birth weight and correlations with adult disease",

author = "M Horikoshi and RN Beaumont and FR Day and NM Warrington and Marjolein Kooijman and J Fernandez-Tajes and B Feenstra and \{van Zuydam\}, NR and KJ Gaulton and N Grarup and JP Bradfield and DP Strachan and R Li-Gao and TS Ahluwalia and E Kreiner and R Rueedi and LP Lyytikainen and DL Cousminer and Fenny Wu and E Thiering and CA Wang and CT Have and Hottenga, \{JJ (Jouke Jan)\} and N Vilor-Tejedor and PK Joshi and ETH Boh and I Ntalla and N Pitkanen and A Mahajan and Elisa Leeuwen and R Joro and V Lagou and M Nodzenski and LA Diver and KT Zondervan and M Bustamante and P Marques-Vidal and JM Mercader and AJ Bennett and N Rahmioglu and DR Nyholt and RCW Ma and CHT Tam and WH Tam and SK Ganesh and \{van Rooij\}, FJA and SE Jones and PR Loh and KS Ruth and MA Tuke and J Tyrrell and AR Wood and H Yaghootkar and DM Scholtens and L Paternoster and I Prokopenko and P Kovacs and M Atalay and SM Willems and K Panoutsopoulou and X Wang and L Carstensen and F Geller and KE Schraut and M Murcia and \{van Beijsterveldt\}, \{CEM (Toos)\} and G Willemsen and EVR Appel and CE Fonvig and C Trier and CMT Tiesler and M Standl and Z Kutalik and S Bonas-Guarch and DM Hougaard and F Sanchez and D Torrents and J Waage and MV Hollegaard and \{de Haan\}, HG and FR Rosendaal and C Medina-Gomez and SM Ring and G Hemani and G McMahon and NR Robertson and CJ Groves and C Langenberg and J Luan and RA Scott and JH Zhao and FD Mentch and SM MacKenzie and RM Reynolds and WL Lowe and A Tonjes and M Stumvoll and V Lindi and TA Lakka and Cornelia Duijn and W Kiess and A Korner and TIA Sorensen and H Niinikoski and K Pahkala and OT Raitakari and E Zeggini and GV Dedoussis and YY Teo and SM Saw and M Melbye and H Campbell and JF Wilson and M Vrijheid and \{de Geus\}, EJCN and DI Boomsma and HN Kadarmideen and JC Holm and T Hansen and S Sebert and AT Hattersley and LJ Beilin and JP Newnham and CE Pennell and Heinrich, \{J (Joachim)\} and LS Adair and JB Borja and KL Mohlke and JG Eriksson and E Widen and M Kahonen and JS Viikari and T Lehtimaki and P Vollenweider and K Bonnelykke and H Bisgaard and Dennis Mook and Bert Hofman and Fernando Rivadeneira and Andr{\'e} Uitterlinden and C Pisinger and O Pedersen and C Power and E Hypponen and NJ Wareham and H Hakonarson and E Davies and BR Walker and Vincent Jaddoe and MR Jarvelin and SFA Grant and AA Vaag and DA Lawlor and TM Frayling and GD Smith and AP Morris and KK Ong and Janine Felix and NJ Timpson and JRB Perry and DM Evans and MI McCarthy and RM Freathy",

year = "2016",

doi = "10.1038/nature19806",

language = "Undefined/Unknown",

volume = "538",

pages = "248--252",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Research",

number = "7624",

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Horikoshi, M, Beaumont, RN, Day, FR, Warrington, NM, Kooijman, M, Fernandez-Tajes, J, Feenstra, B, van Zuydam, NR, Gaulton, KJ, Grarup, N, Bradfield, JP, Strachan, DP, Li-Gao, R, Ahluwalia, TS, Kreiner, E, Rueedi, R, Lyytikainen, LP, Cousminer, DL, Wu, F, Thiering, E, Wang, CA, Have, CT, Hottenga, JJ, Vilor-Tejedor, N, Joshi, PK, Boh, ETH, Ntalla, I, Pitkanen, N, Mahajan, A, Leeuwen, E, Joro, R, Lagou, V, Nodzenski, M, Diver, LA, Zondervan, KT, Bustamante, M, Marques-Vidal, P, Mercader, JM, Bennett, AJ, Rahmioglu, N, Nyholt, DR, Ma, RCW, Tam, CHT, Tam, WH, Ganesh, SK, van Rooij, FJA, Jones, SE, Loh, PR, Ruth, KS, Tuke, MA, Tyrrell, J, Wood, AR, Yaghootkar, H, Scholtens, DM, Paternoster, L, Prokopenko, I, Kovacs, P, Atalay, M, Willems, SM, Panoutsopoulou, K, Wang, X, Carstensen, L, Geller, F, Schraut, KE, Murcia, M, van Beijsterveldt, CEM, Willemsen, G, Appel, EVR, Fonvig, CE, Trier, C, Tiesler, CMT, Standl, M, Kutalik, Z, Bonas-Guarch, S, Hougaard, DM, Sanchez, F, Torrents, D, Waage, J, Hollegaard, MV, de Haan, HG, Rosendaal, FR, Medina-Gomez, C, Ring, SM, Hemani, G, McMahon, G, Robertson, NR, Groves, CJ, Langenberg, C, Luan, J, Scott, RA, Zhao, JH, Mentch, FD, MacKenzie, SM, Reynolds, RM, Lowe, WL, Tonjes, A, Stumvoll, M, Lindi, V, Lakka, TA, Duijn, C, Kiess, W, Korner, A, Sorensen, TIA, Niinikoski, H, Pahkala, K, Raitakari, OT, Zeggini, E, Dedoussis, GV, Teo, YY, Saw, SM, Melbye, M, Campbell, H, Wilson, JF, Vrijheid, M, de Geus, EJCN, Boomsma, DI, Kadarmideen, HN, Holm, JC, Hansen, T, Sebert, S, Hattersley, AT, Beilin, LJ, Newnham, JP, Pennell, CE, Heinrich, J, Adair, LS, Borja, JB, Mohlke, KL, Eriksson, JG, Widen, E, Kahonen, M, Viikari, JS, Lehtimaki, T, Vollenweider, P, Bonnelykke, K, Bisgaard, H, Mook, D, Hofman, B , Rivadeneira, F, Uitterlinden, A, Pisinger, C, Pedersen, O, Power, C, Hypponen, E, Wareham, NJ, Hakonarson, H, Davies, E, Walker, BR, Jaddoe, V, Jarvelin, MR, Grant, SFA, Vaag, AA, Lawlor, DA, Frayling, TM, Smith, GD, Morris, AP, Ong, KK, Felix, J, Timpson, NJ, Perry, JRB, Evans, DM, McCarthy, MI & Freathy, RM 2016, 'Genome-wide associations for birth weight and correlations with adult disease', Nature, vol. 538, no. 7624, pp. 248-252. https://doi.org/10.1038/nature19806

TY - JOUR

T1 - Genome-wide associations for birth weight and correlations with adult disease

AU - Horikoshi, M

AU - Beaumont, RN

AU - Day, FR

AU - Warrington, NM

AU - Kooijman, Marjolein

AU - Fernandez-Tajes, J

AU - Feenstra, B

AU - van Zuydam, NR

AU - Gaulton, KJ

AU - Grarup, N

AU - Bradfield, JP

AU - Strachan, DP

AU - Li-Gao, R

AU - Ahluwalia, TS

AU - Kreiner, E

AU - Rueedi, R

AU - Lyytikainen, LP

AU - Cousminer, DL

AU - Wu, Fenny

AU - Thiering, E

AU - Wang, CA

AU - Have, CT

AU - Hottenga, JJ (Jouke Jan)

AU - Vilor-Tejedor, N

AU - Joshi, PK

AU - Boh, ETH

AU - Ntalla, I

AU - Pitkanen, N

AU - Mahajan, A

AU - Leeuwen, Elisa

AU - Joro, R

AU - Lagou, V

AU - Nodzenski, M

AU - Diver, LA

AU - Zondervan, KT

AU - Bustamante, M

AU - Marques-Vidal, P

AU - Mercader, JM

AU - Bennett, AJ

AU - Rahmioglu, N

AU - Nyholt, DR

AU - Ma, RCW

AU - Tam, CHT

AU - Tam, WH

AU - Ganesh, SK

AU - van Rooij, FJA

AU - Jones, SE

AU - Loh, PR

AU - Ruth, KS

AU - Tuke, MA

AU - Tyrrell, J

AU - Wood, AR

AU - Yaghootkar, H

AU - Scholtens, DM

AU - Paternoster, L

AU - Prokopenko, I

AU - Kovacs, P

AU - Atalay, M

AU - Willems, SM

AU - Panoutsopoulou, K

AU - Wang, X

AU - Carstensen, L

AU - Geller, F

AU - Schraut, KE

AU - Murcia, M

AU - van Beijsterveldt, CEM (Toos)

AU - Willemsen, G

AU - Appel, EVR

AU - Fonvig, CE

AU - Trier, C

AU - Tiesler, CMT

AU - Standl, M

AU - Kutalik, Z

AU - Bonas-Guarch, S

AU - Hougaard, DM

AU - Sanchez, F

AU - Torrents, D

AU - Waage, J

AU - Hollegaard, MV

AU - de Haan, HG

AU - Rosendaal, FR

AU - Medina-Gomez, C

AU - Ring, SM

AU - Hemani, G

AU - McMahon, G

AU - Robertson, NR

AU - Groves, CJ

AU - Langenberg, C

AU - Luan, J

AU - Scott, RA

AU - Zhao, JH

AU - Mentch, FD

AU - MacKenzie, SM

AU - Reynolds, RM

AU - Lowe, WL

AU - Tonjes, A

AU - Stumvoll, M

AU - Lindi, V

AU - Lakka, TA

AU - Duijn, Cornelia

AU - Kiess, W

AU - Korner, A

AU - Sorensen, TIA

AU - Niinikoski, H

AU - Pahkala, K

AU - Raitakari, OT

AU - Zeggini, E

AU - Dedoussis, GV

AU - Teo, YY

AU - Saw, SM

AU - Melbye, M

AU - Campbell, H

AU - Wilson, JF

AU - Vrijheid, M

AU - de Geus, EJCN

AU - Boomsma, DI

AU - Kadarmideen, HN

AU - Holm, JC

AU - Hansen, T

AU - Sebert, S

AU - Hattersley, AT

AU - Beilin, LJ

AU - Newnham, JP

AU - Pennell, CE

AU - Heinrich, J (Joachim)

AU - Adair, LS

AU - Borja, JB

AU - Mohlke, KL

AU - Eriksson, JG

AU - Widen, E

AU - Kahonen, M

AU - Viikari, JS

AU - Lehtimaki, T

AU - Vollenweider, P

AU - Bonnelykke, K

AU - Bisgaard, H

AU - Mook, Dennis

AU - Hofman, Bert

AU - Rivadeneira, Fernando

AU - Uitterlinden, André

AU - Pisinger, C

AU - Pedersen, O

AU - Power, C

AU - Hypponen, E

AU - Wareham, NJ

AU - Hakonarson, H

AU - Davies, E

AU - Walker, BR

AU - Jaddoe, Vincent

AU - Jarvelin, MR

AU - Grant, SFA

AU - Vaag, AA

AU - Lawlor, DA

AU - Frayling, TM

AU - Smith, GD

AU - Morris, AP

AU - Ong, KK

AU - Felix, Janine

AU - Timpson, NJ

AU - Perry, JRB

AU - Evans, DM

AU - McCarthy, MI

AU - Freathy, RM

PY - 2016

Y1 - 2016

U2 - 10.1038/nature19806

DO - 10.1038/nature19806

M3 - Article

C2 - 27680694

SN - 0028-0836

VL - 538

SP - 248

EP - 252

JO - Nature

JF - Nature

IS - 7624

ER -