Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

J Kettunen; Ayse Demirkan; P Wurtz; HHM Draisma; T Haller; R Rawal; A Vaarhorst; AJ Kangas; LP Lyytikainen; M Pirinen; R Pool; AP Sarin; P Soininen; T Tukiainen; Q Wang; M Tiainen; T Tynkkynen; Najaf Amin; T Zeller; M Beekman; J Deelen; KW van Dijk; T Esko; JJ Hottenga; Elisa Leeuwen; T Lehtimaki; E Mihailov; RJ Rose; AJM de Craen; C Gieger; M Kahonen; M Perola; S Blankenberg; MJ Savolainen; AJM Verhoeven; J Viikari; G Willemsen; DI Boomsma; Cornelia Duijn; J Eriksson; A Jula; MR Jarvelin; J Kaprio; A Metspalu; O Raitakari; V Salomaa; PE (Eline) Slagboom; M Waldenberger; S Ripatti; M Ala-Korpela

doi:10.1038/ncomms11122

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

J Kettunen
, Ayse Demirkan
, P Wurtz
, HHM Draisma
, T Haller
, R Rawal
, A Vaarhorst
, AJ Kangas
, LP Lyytikainen
, M Pirinen
, R Pool
, AP Sarin
, P Soininen
, T Tukiainen
, Q Wang
, M Tiainen
, T Tynkkynen
, Najaf Amin
, T Zeller
, M Beekman

J Deelen, KW van Dijk, T Esko, JJ Hottenga, Elisa Leeuwen, T Lehtimaki, E Mihailov, RJ Rose, AJM de Craen, C Gieger, M Kahonen, M Perola, S Blankenberg, MJ Savolainen, AJM Verhoeven, J Viikari, G Willemsen, DI Boomsma, Cornelia Duijn, J Eriksson, A Jula, MR Jarvelin, J Kaprio, A Metspalu, O Raitakari, V Salomaa, PE (Eline) Slagboom, M Waldenberger, S Ripatti, M Ala-Korpela

Epidemiology

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

600 Citations (Scopus)

Original language	Undefined/Unknown
Article number	11122
Journal	Nature Communications
Volume	7
DOIs	https://doi.org/10.1038/ncomms11122
Publication status	Published - 2016

Research programs

EMC NIHES-01-64-02

Access to Document

10.1038/ncomms11122

Cite this

Kettunen, J., Demirkan, A., Wurtz, P., Draisma, HHM., Haller, T., Rawal, R., Vaarhorst, A., Kangas, AJ., Lyytikainen, LP., Pirinen, M., Pool, R., Sarin, AP., Soininen, P., Tukiainen, T., Wang, Q., Tiainen, M., Tynkkynen, T., Amin, N., Zeller, T., ... Ala-Korpela, M. (2016). Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. Nature Communications, 7, Article 11122. https://doi.org/10.1038/ncomms11122

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title = "Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA",

author = "J Kettunen and Ayse Demirkan and P Wurtz and HHM Draisma and T Haller and R Rawal and A Vaarhorst and AJ Kangas and LP Lyytikainen and M Pirinen and R Pool and AP Sarin and P Soininen and T Tukiainen and Q Wang and M Tiainen and T Tynkkynen and Najaf Amin and T Zeller and M Beekman and J Deelen and \{van Dijk\}, KW and T Esko and JJ Hottenga and Elisa Leeuwen and T Lehtimaki and E Mihailov and RJ Rose and \{de Craen\}, AJM and C Gieger and M Kahonen and M Perola and S Blankenberg and MJ Savolainen and AJM Verhoeven and J Viikari and G Willemsen and DI Boomsma and Cornelia Duijn and J Eriksson and A Jula and MR Jarvelin and J Kaprio and A Metspalu and O Raitakari and V Salomaa and Slagboom, \{PE (Eline)\} and M Waldenberger and S Ripatti and M Ala-Korpela",

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Kettunen, J, Demirkan, A, Wurtz, P, Draisma, HHM, Haller, T, Rawal, R, Vaarhorst, A, Kangas, AJ, Lyytikainen, LP, Pirinen, M, Pool, R, Sarin, AP, Soininen, P, Tukiainen, T, Wang, Q, Tiainen, M, Tynkkynen, T, Amin, N, Zeller, T, Beekman, M, Deelen, J, van Dijk, KW, Esko, T, Hottenga, JJ, Leeuwen, E, Lehtimaki, T, Mihailov, E, Rose, RJ, de Craen, AJM, Gieger, C, Kahonen, M, Perola, M, Blankenberg, S, Savolainen, MJ, Verhoeven, AJM, Viikari, J, Willemsen, G, Boomsma, DI, Duijn, C, Eriksson, J, Jula, A, Jarvelin, MR, Kaprio, J, Metspalu, A, Raitakari, O, Salomaa, V, Slagboom, PE, Waldenberger, M, Ripatti, S & Ala-Korpela, M 2016, 'Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA', Nature Communications, vol. 7, 11122. https://doi.org/10.1038/ncomms11122

TY - JOUR

T1 - Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

AU - Kettunen, J

AU - Demirkan, Ayse

AU - Wurtz, P

AU - Draisma, HHM

AU - Haller, T

AU - Rawal, R

AU - Vaarhorst, A

AU - Kangas, AJ

AU - Lyytikainen, LP

AU - Pirinen, M

AU - Pool, R

AU - Sarin, AP

AU - Soininen, P

AU - Tukiainen, T

AU - Wang, Q

AU - Tiainen, M

AU - Tynkkynen, T

AU - Amin, Najaf

AU - Zeller, T

AU - Beekman, M

AU - Deelen, J

AU - van Dijk, KW

AU - Esko, T

AU - Hottenga, JJ

AU - Leeuwen, Elisa

AU - Lehtimaki, T

AU - Mihailov, E

AU - Rose, RJ

AU - de Craen, AJM

AU - Gieger, C

AU - Kahonen, M

AU - Perola, M

AU - Blankenberg, S

AU - Savolainen, MJ

AU - Verhoeven, AJM

AU - Viikari, J

AU - Willemsen, G

AU - Boomsma, DI

AU - Duijn, Cornelia

AU - Eriksson, J

AU - Jula, A

AU - Jarvelin, MR

AU - Kaprio, J

AU - Metspalu, A

AU - Raitakari, O

AU - Salomaa, V

AU - Slagboom, PE (Eline)

AU - Waldenberger, M

AU - Ripatti, S

AU - Ala-Korpela, M

PY - 2016

Y1 - 2016

U2 - 10.1038/ncomms11122

DO - 10.1038/ncomms11122

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C2 - 27005778

SN - 2041-1723

VL - 7

JO - Nature Communications

JF - Nature Communications

M1 - 11122

ER -