Glioma EVs Contribute to Immune Privilege in the Brain

Erik R Abels, Marike L D Broekman, Xandra O Breakefield, Sybren L N Maas

Research output: Contribution to journalReview articleAcademicpeer-review

20 Citations (Scopus)


Glioblastoma cells release extracellular vesicles (EVs), sometimes referred to as microvesicles and exosomes, to transfer immune modulating molecules to immune cells, resulting in an immune privileged microenvironment. Here we discuss the potential EV-mediated mechanisms underlying glioma immune modulation, as well as the technical difficulties in studying these interactions.

Original languageEnglish
Pages (from-to)393-396
Number of pages4
JournalTrends in Cancer
Issue number7
Publication statusPublished - Jul 2019
Externally publishedYes

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