Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency

Mateusz Stoszko; AMS Al-Hatmi; A Skriba; Michael Roling; Enrico Ne; Raquel Crespo Galván; Yvonne Müller; MJ Najafzadeh; J Kang; R Ptackova; E LeMasters; P Biswas; A Bertoldi; Tsung Wai Kan; Elisa Crignis; M Sulc; Joyce Lebbink; Casper Rokx; Annelies Verbon; Wilfred Ijcken; Peter Katsikis; Robert-jan Palstra; V Havlicek; S de Hoog; Tokameh Mahmoudi

doi:10.1126/sciadv.aba6617

Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency

Mateusz Stoszko, AMS Al-Hatmi, A Skriba, Michael Roling, Enrico Ne, Raquel Crespo Galván, Yvonne Müller, MJ Najafzadeh, J Kang, R Ptackova, E LeMasters, P Biswas, A Bertoldi, Tsung Wai Kan, Elisa Crignis, M Sulc, Joyce Lebbink, Casper Rokx, Annelies Verbon, Wilfred IjckenPeter Katsikis, Robert-jan Palstra, V Havlicek, S de Hoog, Tokameh Mahmoudi

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Scopus)

Original language	English
Article number	eaha6617
Journal	Science advances
Volume	6
Issue number	33
DOIs	https://doi.org/10.1126/sciadv.aba6617
Publication status	Published - 2020

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Cite this

Stoszko, M., Al-Hatmi, AMS., Skriba, A., Roling, M., Ne, E., Crespo Galván, R., Müller, Y., Najafzadeh, MJ., Kang, J., Ptackova, R., LeMasters, E., Biswas, P., Bertoldi, A., Kan, T. W., Crignis, E., Sulc, M., Lebbink, J., Rokx, C., Verbon, A., ... Mahmoudi, T. (2020). Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency. Science advances, 6(33), [eaha6617]. https://doi.org/10.1126/sciadv.aba6617

Stoszko, Mateusz ; Al-Hatmi, AMS ; Skriba, A ; Roling, Michael ; Ne, Enrico ; Crespo Galván, Raquel ; Müller, Yvonne ; Najafzadeh, MJ ; Kang, J ; Ptackova, R ; LeMasters, E ; Biswas, P ; Bertoldi, A ; Kan, Tsung Wai ; Crignis, Elisa ; Sulc, M ; Lebbink, Joyce ; Rokx, Casper ; Verbon, Annelies ; Ijcken, Wilfred ; Katsikis, Peter ; Palstra, Robert-jan ; Havlicek, V ; de Hoog, S ; Mahmoudi, Tokameh. / Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency. In: Science advances. 2020 ; Vol. 6, No. 33.

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title = "Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency",

author = "Mateusz Stoszko and AMS Al-Hatmi and A Skriba and Michael Roling and Enrico Ne and {Crespo Galv{\'a}n}, Raquel and Yvonne M{\"u}ller and MJ Najafzadeh and J Kang and R Ptackova and E LeMasters and P Biswas and A Bertoldi and Kan, {Tsung Wai} and Elisa Crignis and M Sulc and Joyce Lebbink and Casper Rokx and Annelies Verbon and Wilfred Ijcken and Peter Katsikis and Robert-jan Palstra and V Havlicek and {de Hoog}, S and Tokameh Mahmoudi",

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doi = "10.1126/sciadv.aba6617",

language = "English",

volume = "6",

journal = "Science advances",

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Stoszko, M, Al-Hatmi, AMS, Skriba, A, Roling, M, Ne, E, Crespo Galván, R , Müller, Y, Najafzadeh, MJ, Kang, J, Ptackova, R, LeMasters, E, Biswas, P, Bertoldi, A, Kan, TW, Crignis, E, Sulc, M, Lebbink, J , Rokx, C , Verbon, A , Ijcken, W , Katsikis, P , Palstra, R, Havlicek, V, de Hoog, S & Mahmoudi, T 2020, 'Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency', Science advances, vol. 6, no. 33, eaha6617. https://doi.org/10.1126/sciadv.aba6617

Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency. / Stoszko, Mateusz; Al-Hatmi, AMS; Skriba, A; Roling, Michael; Ne, Enrico; Crespo Galván, Raquel ; Müller, Yvonne; Najafzadeh, MJ; Kang, J; Ptackova, R; LeMasters, E; Biswas, P; Bertoldi, A; Kan, Tsung Wai; Crignis, Elisa; Sulc, M; Lebbink, Joyce ; Rokx, Casper ; Verbon, Annelies ; Ijcken, Wilfred ; Katsikis, Peter ; Palstra, Robert-jan; Havlicek, V; de Hoog, S; Mahmoudi, Tokameh.

In: Science advances, Vol. 6, No. 33, eaha6617, 2020.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency

AU - Stoszko, Mateusz

AU - Al-Hatmi, AMS

AU - Skriba, A

AU - Roling, Michael

AU - Ne, Enrico

AU - Crespo Galván, Raquel

AU - Müller, Yvonne

AU - Najafzadeh, MJ

AU - Kang, J

AU - Ptackova, R

AU - LeMasters, E

AU - Biswas, P

AU - Bertoldi, A

AU - Kan, Tsung Wai

AU - Crignis, Elisa

AU - Sulc, M

AU - Lebbink, Joyce

AU - Rokx, Casper

AU - Verbon, Annelies

AU - Ijcken, Wilfred

AU - Katsikis, Peter

AU - Palstra, Robert-jan

AU - Havlicek, V

AU - de Hoog, S

AU - Mahmoudi, Tokameh

PY - 2020

Y1 - 2020

U2 - 10.1126/sciadv.aba6617

DO - 10.1126/sciadv.aba6617

M3 - Article

VL - 6

JO - Science advances

JF - Science advances

SN - 2375-2548

IS - 33

M1 - eaha6617

ER -