Global mortality from conditions with skin manifestations

Lindsay N. Boyers; Chante Karimkhani; Mohsen Naghavi; David Sherwood; David J. Margolis; Roderick J. Hay; Hywel C. Williams; Luigi Naldi; Luc E. Coffeng; Martin A. Weinstock; Cory A. Dunnick; Hannah Pederson; Theo Vos; Robert P. Dellavalle

doi:10.1016/j.jaad.2014.08.022

Global mortality from conditions with skin manifestations

Lindsay N. Boyers
, Chante Karimkhani
, Mohsen Naghavi
, David Sherwood
, David J. Margolis
, Roderick J. Hay
, Hywel C. Williams
, Luigi Naldi
, Luc E. Coffeng
, Martin A. Weinstock
, Cory A. Dunnick
, Hannah Pederson
, Theo Vos
, Robert P. Dellavalle^*

^*Corresponding author for this work

Georgetown University School of Medicine
Columbia University
Institute for Health Metrics and Evaluation
University of Colorado Boulder
UPenn School of Medicine
King’s College Hospital
University of Nottingham
Azienda Ospedaliera Papa Giovanni XXIII
Brown University
Rhode Island Hospital
University of Colorado Anschutz Medical Campus
Department of Veterans Affairs
University of Colorado School of Medicine
University of Washington

Research output: Contribution to journal › Article › Academic › peer-review

29 Citations (Scopus)

Abstract

Background:

Global Burden of Disease Study is a research database containing systematically compiled information from vital statistics and epidemiologic literature to inform research, public policy, and resource allocation.

Objective:

We sought to compare mortality among conditions with skin manifestations in 50 developed and 137 developing countries from 1990 to 2010.

Methods:

This was a cross-sectional study to calculate mean age-standardized mortality (per 100,000 persons) across countries for 10 disease categories with skin manifestations. We compared differences in mortality from these disorders by time period (year 1990 vs year 2010) and by developing versus developed country status.

Results:

Melanoma death rates were 5.6 and 4.7 times greater in developed compared with developing countries in 1990 and 2010, respectively. Measles death rates in 1990 and 2010 were 345 and 197 times greater in developing countries, and corresponding syphilis death rates were 33 and 45 times greater.

Limitations:

Inability to adjust for patient-, provider-, and geographic-level confounders may limit the accuracy and generalizability of these results.

Conclusion:

The mortality burden from skin-related conditions differs between developing and developed countries, with the greatest differences observed for melanoma, measles, and syphilis. These results may help prioritize and optimize efforts to prevent and treat these disorders.

Original language	English
Pages (from-to)	1137-1143.e17
Journal	Journal of the American Academy of Dermatology
Volume	71
Issue number	6
DOIs	https://doi.org/10.1016/j.jaad.2014.08.022
Publication status	Published - 1 Dec 2014
Externally published	Yes

Bibliographical note

Funding Information:
The Global Burden of Disease Study 2010 was supported in part by the Bill and Melinda Gates Foundation (grant number: OPP43650_01 ).

Publisher Copyright:
© 2014 American Academy of Dermatology, Inc.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.jaad.2014.08.022

Cite this

Boyers, L. N., Karimkhani, C., Naghavi, M., Sherwood, D., Margolis, D. J., Hay, R. J., Williams, H. C., Naldi, L., Coffeng, L. E., Weinstock, M. A., Dunnick, C. A., Pederson, H., Vos, T., & Dellavalle, R. P. (2014). Global mortality from conditions with skin manifestations. Journal of the American Academy of Dermatology, 71(6), 1137-1143.e17. https://doi.org/10.1016/j.jaad.2014.08.022

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title = "Global mortality from conditions with skin manifestations",

abstract = "Background: Global Burden of Disease Study is a research database containing systematically compiled information from vital statistics and epidemiologic literature to inform research, public policy, and resource allocation. Objective: We sought to compare mortality among conditions with skin manifestations in 50 developed and 137 developing countries from 1990 to 2010. Methods: This was a cross-sectional study to calculate mean age-standardized mortality (per 100,000 persons) across countries for 10 disease categories with skin manifestations. We compared differences in mortality from these disorders by time period (year 1990 vs year 2010) and by developing versus developed country status. Results: Melanoma death rates were 5.6 and 4.7 times greater in developed compared with developing countries in 1990 and 2010, respectively. Measles death rates in 1990 and 2010 were 345 and 197 times greater in developing countries, and corresponding syphilis death rates were 33 and 45 times greater. Limitations: Inability to adjust for patient-, provider-, and geographic-level confounders may limit the accuracy and generalizability of these results. Conclusion: The mortality burden from skin-related conditions differs between developing and developed countries, with the greatest differences observed for melanoma, measles, and syphilis. These results may help prioritize and optimize efforts to prevent and treat these disorders.",

author = "Boyers, \{Lindsay N.\} and Chante Karimkhani and Mohsen Naghavi and David Sherwood and Margolis, \{David J.\} and Hay, \{Roderick J.\} and Williams, \{Hywel C.\} and Luigi Naldi and Coffeng, \{Luc E.\} and Weinstock, \{Martin A.\} and Dunnick, \{Cory A.\} and Hannah Pederson and Theo Vos and Dellavalle, \{Robert P.\}",

note = "Funding Information: The Global Burden of Disease Study 2010 was supported in part by the Bill and Melinda Gates Foundation (grant number: OPP43650\_01 ). Publisher Copyright: {\textcopyright} 2014 American Academy of Dermatology, Inc.",

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AU - Boyers, Lindsay N.

AU - Karimkhani, Chante

AU - Naghavi, Mohsen

AU - Sherwood, David

AU - Margolis, David J.

AU - Hay, Roderick J.

AU - Williams, Hywel C.

AU - Naldi, Luigi

AU - Coffeng, Luc E.

AU - Weinstock, Martin A.

AU - Dunnick, Cory A.

AU - Pederson, Hannah

AU - Vos, Theo

AU - Dellavalle, Robert P.

N1 - Funding Information: The Global Burden of Disease Study 2010 was supported in part by the Bill and Melinda Gates Foundation (grant number: OPP43650_01 ). Publisher Copyright: © 2014 American Academy of Dermatology, Inc.

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Background: Global Burden of Disease Study is a research database containing systematically compiled information from vital statistics and epidemiologic literature to inform research, public policy, and resource allocation. Objective: We sought to compare mortality among conditions with skin manifestations in 50 developed and 137 developing countries from 1990 to 2010. Methods: This was a cross-sectional study to calculate mean age-standardized mortality (per 100,000 persons) across countries for 10 disease categories with skin manifestations. We compared differences in mortality from these disorders by time period (year 1990 vs year 2010) and by developing versus developed country status. Results: Melanoma death rates were 5.6 and 4.7 times greater in developed compared with developing countries in 1990 and 2010, respectively. Measles death rates in 1990 and 2010 were 345 and 197 times greater in developing countries, and corresponding syphilis death rates were 33 and 45 times greater. Limitations: Inability to adjust for patient-, provider-, and geographic-level confounders may limit the accuracy and generalizability of these results. Conclusion: The mortality burden from skin-related conditions differs between developing and developed countries, with the greatest differences observed for melanoma, measles, and syphilis. These results may help prioritize and optimize efforts to prevent and treat these disorders.

AB - Background: Global Burden of Disease Study is a research database containing systematically compiled information from vital statistics and epidemiologic literature to inform research, public policy, and resource allocation. Objective: We sought to compare mortality among conditions with skin manifestations in 50 developed and 137 developing countries from 1990 to 2010. Methods: This was a cross-sectional study to calculate mean age-standardized mortality (per 100,000 persons) across countries for 10 disease categories with skin manifestations. We compared differences in mortality from these disorders by time period (year 1990 vs year 2010) and by developing versus developed country status. Results: Melanoma death rates were 5.6 and 4.7 times greater in developed compared with developing countries in 1990 and 2010, respectively. Measles death rates in 1990 and 2010 were 345 and 197 times greater in developing countries, and corresponding syphilis death rates were 33 and 45 times greater. Limitations: Inability to adjust for patient-, provider-, and geographic-level confounders may limit the accuracy and generalizability of these results. Conclusion: The mortality burden from skin-related conditions differs between developing and developed countries, with the greatest differences observed for melanoma, measles, and syphilis. These results may help prioritize and optimize efforts to prevent and treat these disorders.

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JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

IS - 6

ER -

Global mortality from conditions with skin manifestations

Abstract

Bibliographical note

UN SDGs

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