TY - JOUR
T1 - Healthy, mtDNA-mutation free mesoangioblasts from mtDNA patients qualify for autologous therapy
AU - van Tienen, Florence
AU - Zelissen, Ruby
AU - Timmer, Erika
AU - van Gisbergen, Marike
AU - Lindsey, Patrick
AU - Quattrocelli, Mattia
AU - Sampaolesi, Maurilio
AU - den Hartog, N.M. (Elvira)
AU - de Coo, Irenaeus
AU - Smeets, Hubert
PY - 2019/12/21
Y1 - 2019/12/21
N2 - Our data demonstrates that in half of the mtDNA mutation carriers, their mesoangioblasts are (nearly) mutation free and can potentially be used as source for autologous cell therapy for generation of new muscle fibers without mtDNA mutation and normal mitochondrial function.
AB - Our data demonstrates that in half of the mtDNA mutation carriers, their mesoangioblasts are (nearly) mutation free and can potentially be used as source for autologous cell therapy for generation of new muscle fibers without mtDNA mutation and normal mitochondrial function.
U2 - 10.1186/s13287-019-1510-8
DO - 10.1186/s13287-019-1510-8
M3 - Article
C2 - 31864395
SN - 1757-6512
VL - 10
JO - STEM CELL RESEARCH & THERAPY
JF - STEM CELL RESEARCH & THERAPY
IS - 1
M1 - 405
ER -