Hematopoiesis and Lymphocyte Development: An Introduction

Menno C. Van Zelm*, Magdalena B. Rother, Frank J.T. Staal

*Corresponding author for this work

Research output: Chapter/Conference proceedingChapterAcademic


The production of blood and immune cells is a continuous process throughout life and essential for the existence of any individual human being. This process is referred to as HEMATOPOIESIS (from the Greek hematos, blood, and poiein, to generate) and includes the generation of three major cell lineages: (1) ERYTHROCYTES (red cells) that transport oxygen, (2) THROMBOCYTES (platelets) that mediate blood clotting, and (3) LEUKOCYTES (white blood cells) that function in host defense and consist of various types of GRANULOCYTES, LYMPHOCYTES, and MONOCYTES. The major site of HEMATOPOIESIS is the BONE MARROW, but it can occur at other (extramedullary) locations as well.

Original languageEnglish
Title of host publicationNijkamp and Parnham’s Principles of Immunopharmacology
PublisherSpringer International Publishing AG
Number of pages13
EditionFourth revised and extended edition
ISBN (Electronic)9783030108113
ISBN (Print)9783030108090
Publication statusPublished - 1 Jan 2019

Bibliographical note

Publisher Copyright: © Springer International Publishing AG 2019.


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