Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study

Boris Beudeker; Anthonie Groothuismink; Rob de Man; Carlijn Witjes; Annemiek Baltissen - van der Eijk; Andre Boonstra; Milan Sonneveld

doi:10.1111/jvh.13394

Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study

Research output: Contribution to journal › Article › Academic › peer-review

10 Citations (Scopus)

Abstract

Prognosis of hepatitis B (HBV)-associated hepatocellular carcinoma (HCC) is poor due to high rates of HCC recurrence and progression of underlying liver disease. We studied whether serum hepatitis B core-related antigen (HBcrAg) levels could predict HCC recurrence and outcome in HBV associated. Higher HBcrAg levels at HCC diagnosis were independently associated with reduced overall and recurrence-free survival in patients with early, but not advanced, stage HCC.

Original language	English
Pages (from-to)	205-208
Number of pages	4
Journal	Journal of Viral Hepatitis
Volume	28
Issue number	1
DOIs	https://doi.org/10.1111/jvh.13394
Publication status	Published - Jan 2021

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10.1111/jvh.13394Licence: CC BY

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Beudeker, B., Groothuismink, A., de Man, R., Witjes, C., Baltissen - van der Eijk, A., Boonstra, A., & Sonneveld, M. (2021). Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study. Journal of Viral Hepatitis, 28(1), 205-208. https://doi.org/10.1111/jvh.13394

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title = "Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study",

abstract = "Prognosis of hepatitis B (HBV)-associated hepatocellular carcinoma (HCC) is poor due to high rates of HCC recurrence and progression of underlying liver disease. We studied whether serum hepatitis B core-related antigen (HBcrAg) levels could predict HCC recurrence and outcome in HBV associated. Higher HBcrAg levels at HCC diagnosis were independently associated with reduced overall and recurrence-free survival in patients with early, but not advanced, stage HCC.",

author = "Boris Beudeker and Anthonie Groothuismink and \{de Man\}, Rob and Carlijn Witjes and \{Baltissen - van der Eijk\}, Annemiek and Andre Boonstra and Milan Sonneveld",

year = "2021",

month = jan,

doi = "10.1111/jvh.13394",

language = "English",

volume = "28",

pages = "205--208",

journal = "Journal of Viral Hepatitis",

issn = "1352-0504",

publisher = "Wiley-Blackwell Publishing Ltd",

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Beudeker, B , Groothuismink, A, de Man, R, Witjes, C, Baltissen - van der Eijk, A , Boonstra, A & Sonneveld, M 2021, 'Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study', Journal of Viral Hepatitis, vol. 28, no. 1, pp. 205-208. https://doi.org/10.1111/jvh.13394

Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study. / Beudeker, Boris ; Groothuismink, Anthonie; de Man, Rob et al.
In: Journal of Viral Hepatitis, Vol. 28, No. 1, 01.2021, p. 205-208.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study

AU - Beudeker, Boris

AU - Groothuismink, Anthonie

AU - de Man, Rob

AU - Witjes, Carlijn

AU - Baltissen - van der Eijk, Annemiek

AU - Boonstra, Andre

AU - Sonneveld, Milan

PY - 2021/1

Y1 - 2021/1

N2 - Prognosis of hepatitis B (HBV)-associated hepatocellular carcinoma (HCC) is poor due to high rates of HCC recurrence and progression of underlying liver disease. We studied whether serum hepatitis B core-related antigen (HBcrAg) levels could predict HCC recurrence and outcome in HBV associated. Higher HBcrAg levels at HCC diagnosis were independently associated with reduced overall and recurrence-free survival in patients with early, but not advanced, stage HCC.

AB - Prognosis of hepatitis B (HBV)-associated hepatocellular carcinoma (HCC) is poor due to high rates of HCC recurrence and progression of underlying liver disease. We studied whether serum hepatitis B core-related antigen (HBcrAg) levels could predict HCC recurrence and outcome in HBV associated. Higher HBcrAg levels at HCC diagnosis were independently associated with reduced overall and recurrence-free survival in patients with early, but not advanced, stage HCC.

UR - https://www.scopus.com/pages/publications/85090956920

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DO - 10.1111/jvh.13394

M3 - Article

C2 - 32869922

SN - 1352-0504

VL - 28

SP - 205

EP - 208

JO - Journal of Viral Hepatitis

JF - Journal of Viral Hepatitis

IS - 1

ER -

Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study

Abstract

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