TY - JOUR
T1 - Hepatitis D
T2 - advances and challenges
AU - Miao, Zhijiang
AU - Xie, Zhenrong
AU - Ren, Li
AU - Pan, Qiuwei
N1 - Copyright © 2022 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license.
PY - 2022/4/5
Y1 - 2022/4/5
N2 - Hepatitis D virus (HDV) infection causes the most severe form of viral hepatitis with rapid progression to cirrhosis, hepatic decompensation, and hepatocellular carcinoma. Although discovered > 40 years ago, little attention has been paid to this pathogen from both scientific and public communities. However, effectively combating hepatitis D requires advanced scientific knowledge and joint efforts from multi-stakeholders. In this review, we emphasized the recent advances in HDV virology, epidemiology, clinical feature, treatment, and prevention. We not only highlighted the remaining challenges but also the opportunities that can move the field forward.
AB - Hepatitis D virus (HDV) infection causes the most severe form of viral hepatitis with rapid progression to cirrhosis, hepatic decompensation, and hepatocellular carcinoma. Although discovered > 40 years ago, little attention has been paid to this pathogen from both scientific and public communities. However, effectively combating hepatitis D requires advanced scientific knowledge and joint efforts from multi-stakeholders. In this review, we emphasized the recent advances in HDV virology, epidemiology, clinical feature, treatment, and prevention. We not only highlighted the remaining challenges but also the opportunities that can move the field forward.
UR - https://www.scopus.com/pages/publications/85131771283
U2 - 10.1097/cm9.0000000000002011
DO - 10.1097/cm9.0000000000002011
M3 - Review article
C2 - 35234694
SN - 0366-6999
VL - 135
SP - 767
EP - 773
JO - Chinese Medical Journal
JF - Chinese Medical Journal
IS - 7
ER -