TY - JOUR
T1 - Hepatobiliary tumor organoids for personalized medicine
T2 - a multicenter view on establishment, limitations, and future directions
AU - van Tienderen, Gilles S.
AU - Li, Ling
AU - Broutier, Laura
AU - Saito, Yoshimasa
AU - Inacio, Patricia
AU - Huch, Meritxell
AU - Selaru, Florin M.
AU - van der Laan, Luc J.W.
AU - Verstegen, Monique M.A.
N1 - Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2022/3/14
Y1 - 2022/3/14
N2 - Reliable establishment of tumor organoids is paramount to advance applications of organoid technology for personalized medicine. Here, we share our multi-center experience on initiation and tumorigenic confirmation of hepatobiliary cancer organoids. We discuss current concerns, propose potential solutions, and provide future perspectives for improvements in hepatobiliary cancer organoid establishment.
AB - Reliable establishment of tumor organoids is paramount to advance applications of organoid technology for personalized medicine. Here, we share our multi-center experience on initiation and tumorigenic confirmation of hepatobiliary cancer organoids. We discuss current concerns, propose potential solutions, and provide future perspectives for improvements in hepatobiliary cancer organoid establishment.
UR - https://www.scopus.com/pages/publications/85125895436
U2 - 10.1016/j.ccell.2022.02.001
DO - 10.1016/j.ccell.2022.02.001
M3 - Comment/Letter to the editor
C2 - 35148815
AN - SCOPUS:85125895436
SN - 1535-6108
VL - 40
SP - 226
EP - 230
JO - Cancer Cell
JF - Cancer Cell
IS - 3
ER -
