Hepatocellular carcinoma after danazol treatment for hereditary angio-oedema

AEM Berkel, DE Bouman, MR Schaafsma, Kees Verhoef, JM Klaase

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Abstract

Hereditary angio-oedema is characterised by recurrent episodes of laryngeal, intra-abdominal, facial or peripheral oedema. Danazol can be used as prophylaxis for recurrent attacks. Hepatotoxicity is a recognised adverse effect of danazol. We report an exceptional case of a danazol-induced hepatocellular carcinoma in a 75-year-old patient with hereditary angio-oedema.
Original languageUndefined/Unknown
Pages (from-to)380-382
Number of pages3
JournalNetherlands Journal of Medicine
Volume72
Issue number7
Publication statusPublished - 2014

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