Hepatocellular Carcinoma: Unraveling the Role of Occult Hepatitis B Virus Infection

Ângelo Z. Mattos, Angelo A. Mattos, Jose D. Debes

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

1 Citation (Scopus)
29 Downloads (Pure)


In summary, we praise the authors for their important contribution to the field of hepatocarcinogenesis, especially in association to hepatitis B infection. However, we believe the next efforts should be focused on understanding whether these findings apply to other populations at risk before providing patient-care recommendations that could exacerbate costs with unclear clinical benefit. In this regard, we hope studies such as our ESCALON Project or the Texas HCC Consortium Cohort Study would help to further understand HCC development in OBI and lead to the development of better screening methods for HCC.
Original languageEnglish
Pages (from-to)407-408
Number of pages2
JournalClinical Gastroenterology and Hepatology
Issue number2
Publication statusPublished - 1 Feb 2021

Bibliographical note

Funding: Supported by the Robert Wood Johnson Foundation , AFMDP, and NIH-NCI R21 CA215883-01A1 to J.D.D.

Research programs

  • EMC OR-01


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