TY - JOUR
T1 - Herpes simplex infection in a juvenile orangutan (Pongo pygmaeus pygmaeus)
AU - Kik, Maria J.L.
AU - Bos, Jan H.
AU - Groen, Jan
AU - Dorresteijn, Gerry M.
PY - 2005/3/1
Y1 - 2005/3/1
N2 - A juvenile orangutan (Pongo pygmaeus pygmaeus) died after 8 days of diarrhea and vomiting. Necropsy showed petechial hemorrhages in the skin, the myocardium, and the peritoneal membranes. The lungs were hyperemic and edematous, and the liver and spleen were enlarged. Histologic changes consisted of interstitial pneumonia, hepatitis, and splenic hyperplasia. Numerous eosinophilic intranuclear inclusion bodies were visible in pulmonary epithelial cells, hepatocytes, and splenic endothelial cells. Electron microscopic examination revealed herpesvirus in hepatocyte nuclei. Polymerase chain reaction of liver tissue demonstrated the presence of a herpes simplex virus-1.
AB - A juvenile orangutan (Pongo pygmaeus pygmaeus) died after 8 days of diarrhea and vomiting. Necropsy showed petechial hemorrhages in the skin, the myocardium, and the peritoneal membranes. The lungs were hyperemic and edematous, and the liver and spleen were enlarged. Histologic changes consisted of interstitial pneumonia, hepatitis, and splenic hyperplasia. Numerous eosinophilic intranuclear inclusion bodies were visible in pulmonary epithelial cells, hepatocytes, and splenic endothelial cells. Electron microscopic examination revealed herpesvirus in hepatocyte nuclei. Polymerase chain reaction of liver tissue demonstrated the presence of a herpes simplex virus-1.
UR - https://www.researchgate.net/publication/6491391_Herpes_simplex_infection_in_a_juvenile_orangutan_Pongo_pygmaeus_pygmaeus
U2 - 10.1638/03-004
DO - 10.1638/03-004
M3 - Article
C2 - 17315472
SN - 1042-7260
VL - 36
SP - 131
EP - 134
JO - Journal of Zoo and Wildlife Medicine
JF - Journal of Zoo and Wildlife Medicine
IS - 1
ER -
