TY - JOUR
T1 - High prevalence of ST-78 infection-associated vancomycin-resistant Enterococcus faecium from hospitals in Asuncion, Paraguay
AU - Khan, Mushtaq
AU - Northwood, JB
AU - Loor, Rivkah
AU - Tholen, ATR
AU - Riera, E
AU - Falcon, M
AU - Belkum, Alex
AU - van Westreenen, Mireille
AU - Hays, John
PY - 2010
Y1 - 2010
N2 - Forty infection-associated VanA-type vancomycin-resistant Enterococcus faecium (VRE) strains obtained from five collaborating hospitals in Asuncion, Paraguay were investigated. Genotyping using pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing revealed the presence of 17 cluster types and four STs, with 93% (37/40) of isolates comprising ST type 78. Other ST types included ST-132, ST-210 and one new ST type (ST-438). All but one isolate (ST-438) were associated with clonal complex 17 (CC17), and 97% of the total isolates carried the esp gene. Three Tn1546 variants were found, including a new lineage containing an ISEfa5 insertion in an existing IS1251 element.
AB - Forty infection-associated VanA-type vancomycin-resistant Enterococcus faecium (VRE) strains obtained from five collaborating hospitals in Asuncion, Paraguay were investigated. Genotyping using pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing revealed the presence of 17 cluster types and four STs, with 93% (37/40) of isolates comprising ST type 78. Other ST types included ST-132, ST-210 and one new ST type (ST-438). All but one isolate (ST-438) were associated with clonal complex 17 (CC17), and 97% of the total isolates carried the esp gene. Three Tn1546 variants were found, including a new lineage containing an ISEfa5 insertion in an existing IS1251 element.
U2 - 10.1111/j.1469-0691.2009.02898.x
DO - 10.1111/j.1469-0691.2009.02898.x
M3 - Article
C2 - 19622078
SN - 1198-743X
VL - 16
SP - 624
EP - 627
JO - Clinical Microbiology and Infection
JF - Clinical Microbiology and Infection
IS - 6
ER -