High-sensitivity troponin T and N-terminal pro-brain natriuretic peptide in prediction of outcome in congenital diaphragmatic hernia: Results from a Multicenter, Randomized controlled trial

Kitty G. Snoek; Ulrike S. Kraemer; Chantal A. Ten Kate; Anne Greenough; Arno Van Heijst; Irma Capolupo; Thomas Schaible; Joost Van Rosmalen; René M. Wijnen; Irwin K.M. Reiss; Dick Tibboel

doi:10.1016/j.jpeds.2016.03.026

High-sensitivity troponin T and N-terminal pro-brain natriuretic peptide in prediction of outcome in congenital diaphragmatic hernia: Results from a Multicenter, Randomized controlled trial

Kitty G. Snoek, Ulrike S. Kraemer, Chantal A. Ten Kate, Anne Greenough, Arno Van Heijst, Irma Capolupo, Thomas Schaible, Joost Van Rosmalen, René M. Wijnen, Irwin K.M. Reiss, Dick Tibboel

Research output: Contribution to journal › Article › Academic › peer-review

22 Citations (Scopus)

Abstract

Biomarkers may be helpful in prediction of outcomes of infants with congenital diaphragmatic hernia. The predictive value of high-sensitivity troponin T and N-terminal pro-brain natriuretic peptide was investigated in 128 infants with congenital diaphragmatic hernia. After correction for multiple testing, those biomarkers did not predict severe pulmonary hypertension, death, need of extracorporeal membrane oxygenation, or bronchopulmonary dysplasia. Trial registration Netherlands Trial Registry: 1310.

Original language	English
Pages (from-to)	245-249.e4
Journal	Journal of Pediatrics
Volume	173
DOIs	https://doi.org/10.1016/j.jpeds.2016.03.026
Publication status	Published - Jun 2016

Bibliographical note

Funding Information:
Supported by Stichting Sophia Wetenschappelijk Onderzoek and the Willem H. Kröger Foundation (549) . The authors declare no conflicts of interest.

Publisher Copyright:
© 2016 Elsevier Inc. All rights reserved.

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Snoek, K. G., Kraemer, U. S., Ten Kate, C. A., Greenough, A., Van Heijst, A., Capolupo, I., Schaible, T., Van Rosmalen, J., Wijnen, R. M., Reiss, I. K. M., & Tibboel, D. (2016). High-sensitivity troponin T and N-terminal pro-brain natriuretic peptide in prediction of outcome in congenital diaphragmatic hernia: Results from a Multicenter, Randomized controlled trial. Journal of Pediatrics, 173, 245-249.e4. https://doi.org/10.1016/j.jpeds.2016.03.026

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title = "High-sensitivity troponin T and N-terminal pro-brain natriuretic peptide in prediction of outcome in congenital diaphragmatic hernia: Results from a Multicenter, Randomized controlled trial",

abstract = "Biomarkers may be helpful in prediction of outcomes of infants with congenital diaphragmatic hernia. The predictive value of high-sensitivity troponin T and N-terminal pro-brain natriuretic peptide was investigated in 128 infants with congenital diaphragmatic hernia. After correction for multiple testing, those biomarkers did not predict severe pulmonary hypertension, death, need of extracorporeal membrane oxygenation, or bronchopulmonary dysplasia. Trial registration Netherlands Trial Registry: 1310.",

author = "Snoek, \{Kitty G.\} and Kraemer, \{Ulrike S.\} and \{Ten Kate\}, \{Chantal A.\} and Anne Greenough and \{Van Heijst\}, Arno and Irma Capolupo and Thomas Schaible and \{Van Rosmalen\}, Joost and Wijnen, \{Ren{\'e} M.\} and Reiss, \{Irwin K.M.\} and Dick Tibboel",

note = "Funding Information: Supported by Stichting Sophia Wetenschappelijk Onderzoek and the Willem H. Kr{\"o}ger Foundation (549) . The authors declare no conflicts of interest. Publisher Copyright: {\textcopyright} 2016 Elsevier Inc. All rights reserved.",

year = "2016",

month = jun,

doi = "10.1016/j.jpeds.2016.03.026",

language = "English",

volume = "173",

pages = "245--249.e4",

journal = "Journal of Pediatrics",

issn = "0022-3476",

publisher = "Elsevier Inc.",

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Snoek, KG, Kraemer, US, Ten Kate, CA, Greenough, A, Van Heijst, A, Capolupo, I, Schaible, T, Van Rosmalen, J, Wijnen, RM , Reiss, IKM & Tibboel, D 2016, 'High-sensitivity troponin T and N-terminal pro-brain natriuretic peptide in prediction of outcome in congenital diaphragmatic hernia: Results from a Multicenter, Randomized controlled trial', Journal of Pediatrics, vol. 173, pp. 245-249.e4. https://doi.org/10.1016/j.jpeds.2016.03.026

High-sensitivity troponin T and N-terminal pro-brain natriuretic peptide in prediction of outcome in congenital diaphragmatic hernia: Results from a Multicenter, Randomized controlled trial. / Snoek, Kitty G.; Kraemer, Ulrike S.; Ten Kate, Chantal A. et al.
In: Journal of Pediatrics, Vol. 173, 06.2016, p. 245-249.e4.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - High-sensitivity troponin T and N-terminal pro-brain natriuretic peptide in prediction of outcome in congenital diaphragmatic hernia

T2 - Results from a Multicenter, Randomized controlled trial

AU - Snoek, Kitty G.

AU - Kraemer, Ulrike S.

AU - Ten Kate, Chantal A.

AU - Greenough, Anne

AU - Van Heijst, Arno

AU - Capolupo, Irma

AU - Schaible, Thomas

AU - Van Rosmalen, Joost

AU - Wijnen, René M.

AU - Reiss, Irwin K.M.

AU - Tibboel, Dick

N1 - Funding Information: Supported by Stichting Sophia Wetenschappelijk Onderzoek and the Willem H. Kröger Foundation (549) . The authors declare no conflicts of interest. Publisher Copyright: © 2016 Elsevier Inc. All rights reserved.

PY - 2016/6

Y1 - 2016/6

N2 - Biomarkers may be helpful in prediction of outcomes of infants with congenital diaphragmatic hernia. The predictive value of high-sensitivity troponin T and N-terminal pro-brain natriuretic peptide was investigated in 128 infants with congenital diaphragmatic hernia. After correction for multiple testing, those biomarkers did not predict severe pulmonary hypertension, death, need of extracorporeal membrane oxygenation, or bronchopulmonary dysplasia. Trial registration Netherlands Trial Registry: 1310.

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ER -

High-sensitivity troponin T and N-terminal pro-brain natriuretic peptide in prediction of outcome in congenital diaphragmatic hernia: Results from a Multicenter, Randomized controlled trial

Abstract

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