High-speed intracoronary optical frequency domain imaging: implications for three-dimensional reconstruction and quantitative analysis

Takayuki Okamura, Yoshinobu Onuma, Hector Garcia Garcia, Nico Bruining, PWJC (Patrick) Serruys

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29 Citations (Scopus)


Aim: To assess the reproducibility of quantitative analysis of optical frequency domain imaging (OFDI) acquired at different pullback speeds (20, 30, 40 mm/sec), as well as the impact of cardiac motion artefact on three-dimensional (3D) reconstructions. Methods and results: A total of 36 OFDI pullbacks were obtained pre- and post-stent implantation at the pullback speeds of 20, 30 and 40 mm/sec in non-diseased swine coronary arteries. The amount of x-ray contrast needed for blood clearance during OFDI imaging was recorded. Three-dimensional images of stented segments were rendered and artefacts on 3D images were assessed. Lumen areas (LA) were measured on each individual frame in pre- and post-stent pullbacks. The volume of contrast used with a Conclusions: Quantitative analysis of OFDI obtained at different pullback speeds in non-stented coronary arteries could potentially vary in LA measurement. OFDI with high-speed pullback allows quantitative analysis of stented vessels while reducing the amount of contrast and cardiac motion artefacts.
Original languageUndefined/Unknown
Pages (from-to)1216-1226
Number of pages11
Issue number10
Publication statusPublished - 2012

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