Highly non-linear contrast agent oscillations: The compression-only behavior

S. M. Van Der Meer; P. G. Marmottant; S. Hilgenfeldt; M. Versluis; D. Lohse; C. T. Chin; A. Bouakaz; F. Mastik; M. Emmer; N. De Jong

doi:10.1109/ULTSYM.2005.1603012

Highly non-linear contrast agent oscillations: The compression-only behavior

S. M. Van Der Meer^*
, P. G. Marmottant
, S. Hilgenfeldt
, M. Versluis
, D. Lohse
, C. T. Chin
, A. Bouakaz
, F. Mastik
, M. Emmer
, N. De Jong

^*Corresponding author for this work

University of Twente

Research output: Chapter/Conference proceeding › Conference proceeding › Academic › peer-review

3 Citations (Scopus)

Abstract

Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.

Original language	English
Title of host publication	2005 IEEE Ultrasonics Symposium
Pages	974-976
Number of pages	3
DOIs	https://doi.org/10.1109/ULTSYM.2005.1603012
Publication status	Published - 2005
Event	2005 IEEE Ultrasonics Symposium - Rotterdam, Netherlands Duration: 18 Sept 2005 → 21 Sept 2005

Publication series

Series	Proceedings - IEEE Ultrasonics Symposium
Volume	2
ISSN	1051-0117

Conference

Conference	2005 IEEE Ultrasonics Symposium
Country/Territory	Netherlands
City	Rotterdam
Period	18/09/05 → 21/09/05

Access to Document

10.1109/ULTSYM.2005.1603012

Cite this

@inproceedings{51c144d9b77f46d4a7001803c6b0365b,

title = "Highly non-linear contrast agent oscillations: The compression-only behavior",

abstract = "Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33\% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.",

author = "\{Van Der Meer\}, \{S. M.\} and Marmottant, \{P. G.\} and S. Hilgenfeldt and M. Versluis and D. Lohse and Chin, \{C. T.\} and A. Bouakaz and F. Mastik and M. Emmer and \{De Jong\}, N.",

year = "2005",

doi = "10.1109/ULTSYM.2005.1603012",

language = "English",

isbn = "0780393821",

series = "Proceedings - IEEE Ultrasonics Symposium",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

pages = "974--976",

booktitle = "2005 IEEE Ultrasonics Symposium",

note = "2005 IEEE Ultrasonics Symposium ; Conference date: 18-09-2005 Through 21-09-2005",

}

Van Der Meer, SM, Marmottant, PG, Hilgenfeldt, S, Versluis, M, Lohse, D, Chin, CT, Bouakaz, A, Mastik, F, Emmer, M & De Jong, N 2005, Highly non-linear contrast agent oscillations: The compression-only behavior. in 2005 IEEE Ultrasonics Symposium., 1603012, Proceedings - IEEE Ultrasonics Symposium, vol. 2, pp. 974-976, 2005 IEEE Ultrasonics Symposium, Rotterdam, Netherlands, 18/09/05. https://doi.org/10.1109/ULTSYM.2005.1603012

TY - GEN

T1 - Highly non-linear contrast agent oscillations

T2 - 2005 IEEE Ultrasonics Symposium

AU - Van Der Meer, S. M.

AU - Marmottant, P. G.

AU - Hilgenfeldt, S.

AU - Versluis, M.

AU - Lohse, D.

AU - Chin, C. T.

AU - Bouakaz, A.

AU - Mastik, F.

AU - Emmer, M.

AU - De Jong, N.

PY - 2005

Y1 - 2005

N2 - Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.

AB - Here we report the observation of a highly non-linear bubble response of phospholipid coated contrast agents, termed 'compression-only behavior' where the microbubbles only compress, yet hardly expand. The occurrence of this phenomenon has been studied retrospectively and it was found that 33% of the examined cases show this behavior. The compression-only behavior is described by a newly developed shell model for phospholipid coated bubbles. The model extends previous elastic models with shell compressibility, a buckling radius and a break-up tension. It also predicts large amplitude oscillations, and bubble break-up.

UR - https://www.scopus.com/pages/publications/33847107587

U2 - 10.1109/ULTSYM.2005.1603012

DO - 10.1109/ULTSYM.2005.1603012

M3 - Conference proceeding

AN - SCOPUS:33847107587

SN - 0780393821

SN - 9780780393820

T3 - Proceedings - IEEE Ultrasonics Symposium

SP - 974

EP - 976

BT - 2005 IEEE Ultrasonics Symposium

Y2 - 18 September 2005 through 21 September 2005

ER -

Highly non-linear contrast agent oscillations: The compression-only behavior

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