Abstract
To the Editor:
In their study of homocysteine as a predictive factor for hip fracture in older persons, McLean et al. (May 13 issue) do not thoroughly discuss the role of physical activity, which may influence the association between homocysteine levels and the risk of fracture. Several previous studies and systematic reviews suggested that exercise increases bone mineral density and reduces or prevents bone loss in patients with osteoporosis. Physical activity is also effective in preventing falls. [...]
In their study of homocysteine as a predictive factor for hip fracture in older persons, McLean et al. (May 13 issue) do not thoroughly discuss the role of physical activity, which may influence the association between homocysteine levels and the risk of fracture. Several previous studies and systematic reviews suggested that exercise increases bone mineral density and reduces or prevents bone loss in patients with osteoporosis. Physical activity is also effective in preventing falls. [...]
| Original language | English |
|---|---|
| Pages (from-to) | 1027-30; author reply 1027-30 |
| Journal | The New England journal of medicine |
| Volume | 351 |
| Issue number | 10 |
| DOIs |
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| Publication status | Published - 2 Sept 2004 |