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Hormone Replacement Therapy

  • Joseph A.M.J.L. Janssen*
  • , Aart Jan Van Der Lely
  • , Alan D. Rogol
  • , Adriana G. Ioachimescu
  • *Corresponding author for this work
  • Erasmus University Rotterdam
  • Indiana University School of Medicine
  • University of Virginia
  • Emory University
  • Emory University School of Medicine

Research output: Chapter/Conference proceedingChapterAcademic

Abstract

The chapter begins with a discussion on growth hormone deficiency (GHD) in adults. The goals of GH therapy differ in children and adults. The chapter lists the causes of childhood-onset GHD as well as adult-onset GHD. GHD occurs when the pituitary gland is unable to produce sufficient quantities of GH to carry out its growth and metabolic tasks. Presently, the insulin tolerance test (ITT) and the growth hormone releasing hormone (GHRH)+arginine are considered the best tests to diagnose GHD. The chapter briefly discusses topics relevant to GHD in children and adolescents, such as recombinant human growth hormone treatment. It ends with a discussion on pituitary hormone replacement in women. Topics discussed include treatment of adrenocortotropic hormone (ACTH) deficiency, treatment of thyroid stimulating hormone (TSH) deficiency, gonadotroph deficiency, androgen replacement, GH replacement therapy, and vasopressin replacement therapy.

Original languageEnglish
Title of host publicationPituitary Disorders
Subtitle of host publicationDiagnosis and Management
PublisherWiley-Blackwell
Pages265-276
Number of pages12
ISBN (Print)9780470672013
DOIs
Publication statusPublished - 8 Mar 2013

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