TY - JOUR
T1 - Human actinomycetoma caused by Actinomadura mexicana in Sudan
T2 - the first report
AU - Siddig, Emmanuel Edwar
AU - Nyuykonge, Bertrand
AU - Ahmed, Mohammed Tayfour
AU - Hassan, Rowa
AU - Saad, Eiman Siddig Ahmed
AU - Mhmoud, Najwa Adam
AU - Bakhiet, Sahar Mubarak
AU - van de Sande, Wendy W.J.
AU - Fahal, Ahmed Hassan
N1 - Publisher Copyright:
© The Author(s) 2020. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.
PY - 2021/4/14
Y1 - 2021/4/14
N2 - Mycetoma is a localized, chronic, granulomatous disease that can be caused by fungi (eumycetoma) or bacteria (actinomycetoma). Of the 70 different causative agents implicated in mycetoma worldwide, Actinomadura madurae is the only one that causes multiple cases on all continents. Recently, new Actinomadura species were described as causative agents of human mycetoma. One of these new causative agents was Actinomadura mexicana, which was identified in Latin America. Here we demonstrate that this causative agent is not confined to Latin America and that it is also a causative agent of actinomycetoma in Sudan. The disease was managed by antibiotic treatment alone and resulted in complete cure after 6 months of treatment, which is quick when compared with actinomycetoma cases caused by other Actinomadura species.
AB - Mycetoma is a localized, chronic, granulomatous disease that can be caused by fungi (eumycetoma) or bacteria (actinomycetoma). Of the 70 different causative agents implicated in mycetoma worldwide, Actinomadura madurae is the only one that causes multiple cases on all continents. Recently, new Actinomadura species were described as causative agents of human mycetoma. One of these new causative agents was Actinomadura mexicana, which was identified in Latin America. Here we demonstrate that this causative agent is not confined to Latin America and that it is also a causative agent of actinomycetoma in Sudan. The disease was managed by antibiotic treatment alone and resulted in complete cure after 6 months of treatment, which is quick when compared with actinomycetoma cases caused by other Actinomadura species.
UR - http://www.scopus.com/inward/record.url?scp=85104369233&partnerID=8YFLogxK
U2 - 10.1093/trstmh/traa145
DO - 10.1093/trstmh/traa145
M3 - Article
C2 - 33382899
AN - SCOPUS:85104369233
SN - 0035-9203
VL - 115
SP - 406
EP - 410
JO - Transactions of the Royal Society of Tropical Medicine and Hygiene
JF - Transactions of the Royal Society of Tropical Medicine and Hygiene
IS - 4
ER -