Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer

Wytske van Weerden; C.H. Bangma; Ronald de Wit

doi:10.1038/sj.bjc.6604822

Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer

Research output: Contribution to journal › Article › Academic › peer-review

48 Citations (Scopus)

Abstract

With docetaxel as effective chemotherapy for hormone refractory prostate cancer (HRPC), the number of new treatment combinations for HRPC is expanding demanding a fast-track screening system. This review elaborates on the use of xenograft models to select the most promising combination therapies for entering into phase II clinical trials.

Original language	Undefined/Unknown
Pages (from-to)	13-18
Number of pages	6
Journal	British Journal of Cancer
Volume	100
Issue number	1
DOIs	https://doi.org/10.1038/sj.bjc.6604822
Publication status	Published - 2009

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research programs

EMC MM-03-49-01
EMC MM-03-86-08

Access to Document

10.1038/sj.bjc.6604822

http://hdl.handle.net/1765/27068

Cite this

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title = "Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer",

abstract = "With docetaxel as effective chemotherapy for hormone refractory prostate cancer (HRPC), the number of new treatment combinations for HRPC is expanding demanding a fast-track screening system. This review elaborates on the use of xenograft models to select the most promising combination therapies for entering into phase II clinical trials.",

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