Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

RJ Strawbridge; A Silveira; M den Hoed; S Gustafsson; JA Luan; D Rybin; J Dupuis; RF Li-Gao; Maryam Kavousi; A Dehghan; K Haljas; J Lahti; JR Gadin; A Backlund; U de Faire; K Gertow; P Giral; A Goel; SE Humphries; S Kurl; C Langenberg; LL Lannfelt; L Lind; CCM Lindgren; E Mannarino; Dennis Mook; AP Morris; R de Mutsert; R Rauramaa; P Saliba-Gustafsson; B Sennblad; AJ Smit; AC Syvanen; E Tremoli; F Veglia; B Zethelius; HM Bjorck; JG Eriksson; Bert Hofman; OH Franco Duran; H Watkins; JW Jukema; JC Florez; NJ Wareham; JB Meigs; E Ingelsson; D Baldassarre; A Hamsten

doi:10.1016/j.atherosclerosis.2017.09.031

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

RJ Strawbridge, A Silveira, M den Hoed, S Gustafsson, JA Luan, D Rybin, J Dupuis, RF Li-Gao, Maryam Kavousi, A Dehghan, K Haljas, J Lahti, JR Gadin, A Backlund, U de Faire, K Gertow, P Giral, A Goel, SE Humphries, S KurlC Langenberg, LL Lannfelt, L Lind, CCM Lindgren, E Mannarino, Dennis Mook, AP Morris, R de Mutsert, R Rauramaa, P Saliba-Gustafsson, B Sennblad, AJ Smit, AC Syvanen, E Tremoli, F Veglia, B Zethelius, HM Bjorck, JG Eriksson, Bert Hofman, OH Franco Duran, H Watkins, JW Jukema, JC Florez, NJ Wareham, JB Meigs, E Ingelsson, D Baldassarre, A Hamsten

Research output: Contribution to journal › Article › Academic › peer-review

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Original language	Undefined/Unknown
Pages (from-to)	196-204
Number of pages	9
Journal	Atherosclerosis
Volume	266
DOIs	https://doi.org/10.1016/j.atherosclerosis.2017.09.031
Publication status	Published - 2017

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10.1016/j.atherosclerosis.2017.09.031

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Cite this

Strawbridge, RJ., Silveira, A., den Hoed, M., Gustafsson, S., Luan, JA., Rybin, D., Dupuis, J., Li-Gao, RF., Kavousi, M., Dehghan, A., Haljas, K., Lahti, J., Gadin, JR., Backlund, A., de Faire, U., Gertow, K., Giral, P., Goel, A., Humphries, SE., ... Hamsten, A. (2017). Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation. Atherosclerosis, 266, 196-204. https://doi.org/10.1016/j.atherosclerosis.2017.09.031

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title = "Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation",

author = "RJ Strawbridge and A Silveira and {den Hoed}, M and S Gustafsson and JA Luan and D Rybin and J Dupuis and RF Li-Gao and Maryam Kavousi and A Dehghan and K Haljas and J Lahti and JR Gadin and A Backlund and {de Faire}, U and K Gertow and P Giral and A Goel and SE Humphries and S Kurl and C Langenberg and LL Lannfelt and L Lind and CCM Lindgren and E Mannarino and Dennis Mook and AP Morris and {de Mutsert}, R and R Rauramaa and P Saliba-Gustafsson and B Sennblad and AJ Smit and AC Syvanen and E Tremoli and F Veglia and B Zethelius and HM Bjorck and JG Eriksson and Bert Hofman and {Franco Duran}, OH and H Watkins and JW Jukema and JC Florez and NJ Wareham and JB Meigs and E Ingelsson and D Baldassarre and A Hamsten",

year = "2017",

doi = "10.1016/j.atherosclerosis.2017.09.031",

language = "Undefined/Unknown",

volume = "266",

pages = "196--204",

journal = "Atherosclerosis",

issn = "0021-9150",

publisher = "Elsevier Ireland Ltd",

}

Strawbridge, RJ, Silveira, A, den Hoed, M, Gustafsson, S, Luan, JA, Rybin, D, Dupuis, J, Li-Gao, RF, Kavousi, M, Dehghan, A, Haljas, K, Lahti, J, Gadin, JR, Backlund, A, de Faire, U, Gertow, K, Giral, P, Goel, A, Humphries, SE, Kurl, S, Langenberg, C, Lannfelt, LL, Lind, L, Lindgren, CCM, Mannarino, E, Mook, D, Morris, AP, de Mutsert, R, Rauramaa, R, Saliba-Gustafsson, P, Sennblad, B, Smit, AJ, Syvanen, AC, Tremoli, E, Veglia, F, Zethelius, B, Bjorck, HM, Eriksson, JG, Hofman, B, Franco Duran, OH, Watkins, H, Jukema, JW, Florez, JC, Wareham, NJ, Meigs, JB, Ingelsson, E, Baldassarre, D & Hamsten, A 2017, 'Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation', Atherosclerosis, vol. 266, pp. 196-204. https://doi.org/10.1016/j.atherosclerosis.2017.09.031

TY - JOUR

T1 - Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

AU - Strawbridge, RJ

AU - Silveira, A

AU - den Hoed, M

AU - Gustafsson, S

AU - Luan, JA

AU - Rybin, D

AU - Dupuis, J

AU - Li-Gao, RF

AU - Kavousi, Maryam

AU - Dehghan, A

AU - Haljas, K

AU - Lahti, J

AU - Gadin, JR

AU - Backlund, A

AU - de Faire, U

AU - Gertow, K

AU - Giral, P

AU - Goel, A

AU - Humphries, SE

AU - Kurl, S

AU - Langenberg, C

AU - Lannfelt, LL

AU - Lind, L

AU - Lindgren, CCM

AU - Mannarino, E

AU - Mook, Dennis

AU - Morris, AP

AU - de Mutsert, R

AU - Rauramaa, R

AU - Saliba-Gustafsson, P

AU - Sennblad, B

AU - Smit, AJ

AU - Syvanen, AC

AU - Tremoli, E

AU - Veglia, F

AU - Zethelius, B

AU - Bjorck, HM

AU - Eriksson, JG

AU - Hofman, Bert

AU - Franco Duran, OH

AU - Watkins, H

AU - Jukema, JW

AU - Florez, JC

AU - Wareham, NJ

AU - Meigs, JB

AU - Ingelsson, E

AU - Baldassarre, D

AU - Hamsten, A

PY - 2017

Y1 - 2017

U2 - 10.1016/j.atherosclerosis.2017.09.031

DO - 10.1016/j.atherosclerosis.2017.09.031

M3 - Article

VL - 266

SP - 196

EP - 204

JO - Atherosclerosis

JF - Atherosclerosis

SN - 0021-9150

ER -