Abstract
In recent years, microRNAs (miRNA) have been demonstrated to be present in body fluids and may therefore serve as diagnostic markers for diseases. By characterizing miRNA profiles in plasma, a miRNA signature may potentially be developed as a diagnostic and risk assessment tool for particular (patho)physiological states. This chapter describes the isolation, purification, identification, and sequencing of human plasma miRNAs.
Original language | English |
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Title of host publication | Osteoporosis and Osteoarthritis |
Editors | Jennifer J. Westendorf, Andre J. van Wijnen |
Chapter | 7 |
Pages | 71-85 |
Number of pages | 15 |
ISBN (Electronic) | 9781493916191 |
DOIs | |
Publication status | Published - 20 Oct 2014 |
Publication series
Series | Methods in Molecular Biology |
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Volume | 1226 |
ISSN | 1064-3745 |
Bibliographical note
Publisher Copyright: © Springer Science+Business Media New York 2015. All rights are reserved.This work was supported by the Netherlands Organization for Scientific Research (NWO; NGI Horizon grant 93511016)
Research programs
- EMC MGC-02-13-02
- EMC MM-01-39-02