Image dissimilarity-based quantification of lung disease from CT

Lauge Sørensen*, Marco Loog, Pechin Lo, Haseem Ashraf, Asger Dirksen, Robert P.W. Duin, Marleen De Bruijne

*Corresponding author for this work

Research output: Chapter/Conference proceedingConference proceedingAcademicpeer-review

21 Citations (Scopus)

Abstract

In this paper, we propose to classify medical images using dissimilarities computed between collections of regions of interest. The images are mapped into a dissimilarity space using an image dissimilarity measure, and a standard vector space-based classifier is applied in this space. The classification output of this approach can be used in computer aided-diagnosis problems where the goal is to detect the presence of abnormal regions or to quantify the extent or severity of abnormalities in these regions. The proposed approach is applied to quantify chronic obstructive pulmonary disease in computed tomography (CT) images, achieving an area under the receiver operating characteristic curve of 0.817. This is significantly better compared to combining individual region classifications into an overall image classification, and compared to common computerized quantitative measures in pulmonary CT.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention, MICCAI2010 - 13th International Conference, Proceedings
Pages37-44
Number of pages8
EditionPART 1
DOIs
Publication statusPublished - 2010
Event13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010 - Beijing, China
Duration: 20 Sept 201024 Sept 2010

Publication series

SeriesLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 1
Volume6361 LNCS
ISSN0302-9743

Conference

Conference13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010
Country/TerritoryChina
CityBeijing
Period20/09/1024/09/10

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