Immune checkpoint skewing might be the cause of continuous immune activation in nasal polyps: New opportunities for therapies

Alex KleinJan*

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademic

1 Citation (Scopus)
3 Downloads (Pure)

Abstract

[Editorial] Chronic rhinosinusitis (CRS) with or without nasal polyps is a localized major upper respiratory tract disease with an unknown cause. Initially, it resembles an infection that has gotten out of control and progressed into severe inflammation, eventually resulting in chronic sinusitis and nasal polyps. Patients with nasal polyps and sinusitis showed persistent symptoms, including nasal obstruction, loss of smell, nasal discharge, and facial pain or pressure, which are clinically the reasons for treating these patients. These issues require basic scientific research, therefore necessitating detailed characterization. There is no adequate translational model available. [...]
Original languageEnglish
Pages (from-to)538-540
Number of pages3
JournalJournal of Allergy and Clinical Immunology
Volume149
Issue number2
Early online date17 Nov 2021
DOIs
Publication statusPublished - 1 Feb 2022

Fingerprint

Dive into the research topics of 'Immune checkpoint skewing might be the cause of continuous immune activation in nasal polyps: New opportunities for therapies'. Together they form a unique fingerprint.

Cite this